Obituary for Lucius Werthmüller

Lucius Werthmüller † 22.5.1958 – 9.4.2021

We are deeply saddened to inform you that Luci Werthmüller, our friend and companion, quite unexpectedly passed away on April 9.

It is hard for us to believe. We were still in email contact during his last days: he was cordial as always, committed, authentic, straightforward. We mourn with his family and friends.

As the President of our Foundation, a task he fulfilled prudently and competently after Dieter Hagenbach’s demise almost five years ago, Luci leaves a deep vacuum in our lives.

For close to thirty years, we came to know and appreciate him as a true friend, a visionary and a loyal companion in numerous projects. It was an unbelievable opportunity to work with someone as friendly, benevolent, helpful and unselfish, and we will sorely miss his mischievous humor, his profound expertise and – last but not least – his palpable connection with the spiritual world.

As President of the Board of our Foundation, Lucius Werthmüller invested a lot of love and energy in Gaia Media projects. The gaiamedia goodnews is published monthly. In cooperation with the Swiss Medical Society for Psycholytic Therapy (SÄPT), the psychedelics consultancy, close to his heart, has been very popular ever since September 2019 and has experienced an unexpected upgrade and pertinence with the intensified scientific research into the therapeutic potential of mind-expanding substances in recent years.

With the opening of the gaialounge and the ethnobotanika store, in September 2020, Luci laid the foundation for our mission – to create a place where people can meet and share ideas in the fields of consciousness, ecology, spirituality and the exploration of consciousness-expanding substances. Luci was highly motivated to contribute to a new understanding of nature within our cultural niche. His commitment also finds expression in our gaia media library and in the workshops, lectures and cultural events to take place there.

With gaialounge, one of Luci’s core interests finds its fulfillment, and we are honored to carry the torch of this involvement out into the world.

Thank you for your love of the cause, your commitment, your persistence, your patience.

We will miss you infinitely.

For the Board:
Dr. Pierre Joset
Kerim Seiler

Obituary for Dieter A. Hagenbach


Obituary for Dieter A. Hagenbach

by Lucius Werthmüller

On Wednesday, 17 August 2016, after a short illness, my friend Dieter Hagenbach – publisher, bookseller, author and founder of the seminal Sphinx Verlag (Sphinx Publishing) – died in Basel at age seventy-three.

Dieter Alfred Hagenbach was born in Basel on 24 July 1943. This is where he grew up and lived most of his life.

Having finished high school, Dieter studied Arts and Architecture at the Art University of Düsseldorf. An educational journey lead him to India, to the matriarchal tribes of eastern Assam, as well as to observatories in Delhi, Jaipur and Varanasi; a research project brought him to London’s Centre for Arts and Cultural Enterprises. In 1969, with Jürgen Rahn, he formed the multimedia team «Cosmic Correspondence» with exhibitions at art spaces in Baden-Baden, Basel and Düsseldorf.

Back in Basel, in the fall of 1975, Dieter founded Sphinx Verlag and opened the Sphinx bookstore. With Sphinx Verlag, he achieved pioneering work for the German speaking countries. Among other notables, he published the complete oeuvre of G.I. Gurdjieff, Necronomicon and further art books by HR Giger as well as classics of magic and mythology ranging from Eliphas Levy and Aleister Crowley to Joseph Campbell. Next to several hundred other titles, he released the New Age bible The Aquarian Conspiracy, by Marilyn Ferguson, the Illuminatus trilogy, by Robert Anton Wilson & Robert Shea, as well as books by John C. Lilly and Timothy Leary, who were his good friends. Thus, in 1971, he briefly hosted Leary while the High Priest of LSD was applying for political asylum in Switzerland, the CIA on his heels. In 1984, Dieter wrote a letter to Dr. Kurt Furgler, then President of the Swiss Confederation, asking that Leary be allowed to re-enter Switzerland. The request was denied.

From 1977 to 1986, Dieter was the publisher of «Sphinx Magazin» and the German edition of the «Brain-Mind Bulletin». In the mid-seventies he met Albert Hofmann, remaining friends with him until the latter’s demise. In 1986, Dieter published Hofmann’s collection of essays Einsichten – Ausblicke (Insights – Outlooks).

In 1990, Dieter founded a literary agency, which, after 2001, was continued by his partner Hans Bender in Bern.

Dieter and I first met in the early nineties, only keeping loose contact. Later in the decade, we collected ideas and designed concepts for a jointly organized conference around the topic of LSD and psychedelics to be held in 1993 – to mark the fiftieth anniversary of its discovery. However, at the time, Albert Hofmann opposed publicity for his «problem child» so we stuck our concepts in a drawer, as a conference around the topic in Basel without him would have required explanation.

1993 marked not only the fiftieth anniversary of the discovery of LSD but also Dieter’s 50th birthday. For this new period of his life, Dieter wished to start a new project – the Gaia Media Foundation (www.gaiamedia.org). The non-profit foundation, established in Basel on 23 June 1993, had the objective of disseminating information leading to a holistic understanding of nature and human life.

He asked me if I would back him as Foundation Councilor, to which I readily agreed. For his milestone birthday Dieter asked for support for his newly initiated structure instead of presents. His birthday party also marked the foundation ceremony for his new baby. In attendance, next to many other friends, were Anita and Albert Hofmann, Claudia Müller Ebeling and Christian Rätsch as well HR Giger, who Dieter knew well, and who I met for the first time on this occasion.

Until 2009, and in collaboration with Michael Gasser, the other half of the Foundation Council, Gaia Media operated the Gaia Lounge and the Gaia Bazaar, a popular stomping ground for lovers of psychedelic as well as spiritual and ecologic literature, also selling a large selection of ethno-botanical specialties. Presentations by Albert Hofmann, Alexander Shulgin, John C. Lilly, Christian Rätsch and Luisa Francia were given among many others. The Gaia Media Foundation published a newsletter, issued in hard copy until 2006. Later Dieter published his newsletter monthly and electronically, in German and in English. He called it his “good news letter” to counterbalance the bad news dominating most media.

In the forefront of Albert Hofmann’s 100th birthday, on 11 January 2006, we retrieved our old ideas and began to make plans for a symposium, «LSD – Problem Child and Miracle Drug» (www.lsd.info). As he grew older, Albert Hofmann successively opened up, supported our project, and ultimately looked forward to it. As a result, we worked closely together and were in contact on an almost daily basis.

On 11 January 2006, in the Museum of Natural History in Basel, the Gaia Media Foundation organized a ceremonial act in honor of Albert Hofmann where his contributions in the field of chemistry were held up both by Representatives of the City of Basel and the Director of Research of Novartis (Novartis was born of the consolidation of the drug companies Sandoz and Ciba-Geigy). The symposium on the following weekend was a tremendous success. Several thousand participants from all continents and a total of thirty-seven countries, as well as around 200 international journalists were in attendance. From The New York Times to The Guardian, the world press commented. The greatest compliment for us, however, was the observation Albert made during the closing session when he declared: «Due to this event, my problem child definitely turned prodigy!»

With the planning of another conference during Easter 2008, our close ties endured. The World Psychedelic Forum (WPF, www.psychedelik.info) was designed as a counterpoint to the World Economic Forum (WEF), in Davos. One month after the event, Albert Hofmann died, only a few days after we had visited him one last time at his beloved Rittimatte. Following his demise, we wanted to honor our friend with an illustrated booklet and a few texts. This work in progress grew steadily, ending as a book of 400 pages, published in German in 2001 and as Mystic Chemist, The Life of Albert Hofmann and his Discovery of LSD, in the US, in 2013. It bears witness to the life of Albert Hofmann, while delivering an encompassing history of LSD and its influence on culture and society.

 

During the two years of research and work on the book, Dieter and I were in steady, almost daily contact, mostly at our offices in Basel. These meetings remain legendary among our colleagues both for our scuffles about details and our wrestling for fitting formulations.

Dieter and I were very different in many ways but we also complemented each other quite nicely. Our quarrels were often heated but never hateful. He was infatuated with detail, precise, organized and structured, and he had an unerring eye for graphic finesse. His outer appearance was carefully groomed; during his later years he always wore white or beige. Everything he did, he did in style, and made an aristocratic impression.

After the publication of the Hofmann biography we gave several presentations together. Luckily, a Californian publisher soon bought the English rights. Dieter worked just as intensely on the translation as he had on the book itself, and thus, for the launching of Mystic Chemist, we traveled to California where we presented the book on 19 April 2013, the sixtieth anniversary of the discovery of LSD, as part of a Conference staged by MAPS (Multidisciplinary Association for Psychedelic Studies, www.maps.org) in Oakland. Dieter was especially pleased with an invitation to present the book at the legendary City Lights Bookstore in San Francisco, where avant-garde Beat authors such as Lawrence Ferlinghetti, Alan Ginsberg or Gregory Corso had been published and had held many readings.

Over the last three years, Dieter mainly published his monthly Newsletter and stayed in touch with his large network all over the world. We didn’t see each other as often anymore. He visited our offices once a week to pick up the mail for the Gaia Media foundation, exchanged a few words with those present, and he and I would talk briefly about current affairs concerning the Foundation or about personal matters.

On 22 July 2016, two days before his birthday, Dieter received the devastating news that made it difficult for him to accept the birthday wishes that reached him from all over on the following Sunday. On the morning of 17 August he told Asti Hagenbach, M.D., he had been in another world that night und that it had been so very beautiful that he had not wanted to come back. In the evening, at 23.40 h, he heaved his last sigh in her presence.

We talked about life after death on several occasions. Dieter was convinced that there was some kind of continuation but didn’t want to visualize it. The Chinese emperor Wu once asked the Indian sage Bodhidharma what the highest meaning of the highest truth is. Bodhidharma answered; “Open space, nothing holy,” an answer befitting Dieters outlook on life.

Dieter leaves behind a brother, Rudy, a sister, Jacqueline, as well as his nephew, Alain Hagenbach.

Thank you, Dieter, for the time we spent together and for our common projects. We both always knew we could not have made it alone.

Journey to Find Iboga

By Bia Labate

Afrique
I landed at the airport in Yaoundé, capital of Cameroon, with the aim of collecting data on a mysterious African root to which powerful therapeutic properties are attributed. The first sensation, the hot and clammy air, is familiar. The pagne, a traditional African garment, makes us feel for a moment that we are back in Salvador, Brazil; but we soon realize that it is not quite “the same thing.” In just a few hours, all our conceptual references have disappeared. To an outsider, there is no coherence or aesthetic order. There are no streets or addresses; traffic is every man for himself. Music 24 hours a day. Men innocently holding hands in the streets. When you walk around the “city,” people stare, make comments, and touch you. As a white person, you want to be invisible.

It’s difficult not to be shocked by Africa, to be immune. Suddenly, it seems that we are waking from a dream: There, before our eyes, a whole continent is throbbing and spreading out its enormous natural wealth and economic poverty. Amidst this scenario, there are thousands of beautiful, creative hairstyles, expressing the power of a people, bewitching and infecting the visitor with a strong sense of joy.

Iboga1
It was not difficult to find the plant. The active components are derived from the underground root of a plant that reaches 1.50 m in height and belongs to the Tabernanthe genus, which is made up of many different species, 650 of which have been identified in Central Africa. The one that has most interested Western medicine is Tabernanthe iboga, found mainly in the region of Cameroon, Gabon, the Central African Republic, the Congo, the Democratic Republic of Congo, Angola, and Equatorial Guinea. The shrub grows in tropical forest areas, swampy soils, or wet savannas. It blooms and produces fruit throughout the year. Its main alkaloid and active ingredient is ibogaine, which is extracted from the bark of the root, and represents 90% of the 30 alkaloids found in the roots of this species. Iboga is formally classified as part of the family of the hallucinogens, which include peyote, mushrooms, LSD and ayahuasca. Alper2 has claimed that its phenomenology is different from classic hallucinogens, and that serotonergic transmission, while generative of hallucinations, is not the cause of ibogaine’s action in opioid withdrawal attenuation.

It is believed that the Pygmies have used iboga since time immemorial. Up until today, these people have used it in rituals that Whites have rarely been permitted to attend. According to the writings of an expert on the plant, the Italian Giorgio Samorini, some species of animals, including mandrills and wild boar, feed on the roots of the iboga to obtain inebriating effects. There is a speculative theory that the Pygmies discovered the hallucinogenic properties of iboga by observing the curious behavior of these animals.3

Ibogaine was first isolated in 1901. It is reported that it was used in the West from the beginning of the century to treat flu, infectious diseases, neurasthenia, and sleep-related illnesses.

In 1962, Howard Lotsof,4 a young heroin-dependent man in search of a new drug experience, discovered iboga. After a trip lasting 36 hours, he said that he had completely lost his craving for heroin and felt no withdrawal symptoms. He gave the substance to seven friends who were also dependent on heroin, and in all cases, the result was the same. In 1983, Lotsof reported the anti-addictive properties of ibogaine, and in 1985, obtained four US patents for the treatment of addiction to opium, cocaine, amphetamines, ethanol, and nicotine. He founded the International Coalition for Addict Self Help (ICASH) and developed the Endabuse method, an experimental pharmacotherapy that makes use of ibogaine HCl, the soluble form of ibogaine. By administering a single dose, the effect of which lasts for two days, considerable or complete attenuation of withdrawal symptoms has been reported, allowing the patient to painlessly detox. There is also allegedly an absence or lessening of the desire to take drugs for some period of time afterward.

The Initiation Rituals of the Bwiti5 Tradition
Currently, iboga is used by traditional healers of the countries of the Congo Basin and the Bwiti religion in Equatorial Guinea, Cameroon, and especially in Gabon, where important members of the political and military hierarchies are congregants. They make use particularly of the bark of the root, but medicinal properties are also attributed to the leaves, the bark of the trunk, and the root itself. In Gabon, the bark of the root and the root are easily found in traditional pharmacies and markets in major cities. There also exists an NGO dedicated entirely to iboga (Association for Nature, Culture, Future: EBANDO). Some claim that, if current trends continue, the collection of wild specimens of the root is putting it at risk of extinction. Iboga may be used alone or in combination with other plants. It is used in the treatment of infertility, depression, snakebites, male impotence, female infertility, AIDS, and also as a stimulant and aphrodisiac. In the belief of local healers, it is also helps to combat “mystical diseases,” such as being possessed.

Tonye Mahop, a researcher at the Limbe Botanical Gardens, says, “there are a number of records of it curing cigarette dependency, mganga (marijuana) and fofo (a local alcohol concentrate made from palm wine) with iboga in the Bwiti rituals. The problem is that the informers do not tell how they prepare and use the plant, so that there is always a part of the knowledge that is kept secret.”

There are two types of Bwiti: the traditional, which rejects Christianity, and the syncretic, which is more widespread. The first is practiced by the Mitsogho, and the later by the Fang, both Bantu groups. It is likely that during the nineteenth century the Pygmies transmitted their knowledge to the Apindji, who in turn passed it on to the Mitsogho, both southern Gabon tribal groups. During the nineteenth century, these groups developed the cult of the dead, which characterizes the traditional Bwiti. The syncretic Bwiti or Fang was formulated at the time of the First World War. This form is the product of traditional Bwiti influences; the traditional ancestor worship of the Fang; the Bieri, who used a different hallucinogenic plant; and Christian evangelization, especially Catholic. Currently, there are at least nine branches of Bwiti. There is also another cult that uses iboga, Abri, which has been little studied. This cult is controlled by women and treats diseases by using medicinal plants and iboga.

Abada Mangue Clavina is President of the Bombo Ima et Bandeei Association (ASSOKOBINAC) of Cameroon and the leader of the Bwiti Dissumba Mono Bata Church in Yaoundé, whose base is his nuclear family consisting of his two wives and 10 children. There are prière  (prayer) sessions every Saturday. He says that there is a specific iboga treatment for problematic drug use that lasts two or three days, depending on the patient and severity of the problem. Two, three, or four teaspoons (4-8 grams) of powdered, scraped, and chopped root bark are administered. “Iboga purifies the blood. We have been successful in 100% of the cases.” The most difficult cases may require an initiation, which costs 200,000 African francs (CFA) (about USD 260.00 in 2011) as opposed to the 50,000 (USD 66.00) that ordinary treatment will cost.

The initiation lasts three days. At the beginning, the candidate confesses all his sins and takes a ritual bath. The climactic moment in the life of the Bwitist is marked by the consumption, after fasting, of an enormous amount of eboka (up to 500 g) and ossoup, a kind of cold tea made from the root of the plant. A group follows the neophyte during the prière, where all sing, play music, and dance into the night.

The initiation ceremony aims at inducing a coma, but scholars have not yet been able to precisely time its duration. According to practitioners, at a certain moment the spirit leaves the body and travels to the level of creation, on the “other side”; in other words, it visits the world of the dead, where one can receive revelations, be healed, or communicate with one’s ancestors. The citar, the “sacred harp,” guides the journey and brings the spirit back to the body. After the ceremony, the subject, reborn with a new identity – that of Bandzi, “he who ate” – must report his visions and experiences in detail. The difference between the Bwiti ritual and that of other rites of passage traditionally studied by anthropologists is that, in this case, death might not be metaphorical or symbolic, but almost real, as it might take the subject to the absolute limit between life and death.

The healer Nanga Nga Owono Justine, initiated 25 years ago in the dissumba of the Bwiti branch, explains: “Eboka is a science that corrects. It is like a door that only opens when a person dies. Eboka has given Black people the chance to visit a place we go to when we die, but we go there before we die, and this is an opportunity to become transformed.” Her mother, the elderly Bilbang Nga Owono Christine, adds: “In order to become healed you have to be convinced, and you will heal yourself. You need the will, eboka, and faith in God, who is the master of everything.” Recalling her own initiation, when she had an “eye disease,” she said that “a star guided me to a hospital on the other side, where my eyes were operated. I saw my spirit leaving my body and the doctors operating me. I returned cured.”

Death may occur in the Bwiti initiation rituals. According to Calvin, this may be the result of several factors. One would be the incompetence or lack of ability of the guerriseur (healer). Another is that eboka cannot be given to someone who is physically too weak. Finally, “if the one undergoing the initiation is a witch or sorcerer, during the trip to the stars, the spirit will want to travel to the zone of darkness and may lose its way and not return, causing the death of the physical body.” The Fang know an antidote, a leaf called ebebing, which they affirm can reverse the effect of the eboka.

The Scientific Version
The scientific literature on the subject is controversial. It is known that ibogaine produces ataxia (loss of body balance), tremors, and lowered body temperature, slowing of heart rate (bradycardia) and lowered blood pressure. Studies in rats have shown that ibogaine in a dosage of 100 mg/kg given intraperitoneally (i.p.) is neurotoxic; a dose considerably higher than the 40 mg/kg i.p. typically used in studies on drug self-administration and withdrawal (the dose in Lotsof’s treatment protocol is usually 15 to 25 mg/kg in humans). It is different from other drugs in that it acts directly to reduce craving and withdrawal by an unknown mechanism in the human body. However, its exact degree of effectiveness is unknown: There are cases of recovery but also of failure. There is no scientific study that proves that ibogaine “cures addiction” – however complicated this notion is–only substantial anecdotal evidence. Similar to reports of death in the Bwiti initiation rites using iboga, there have also been 19 reported deaths as a result of the uncontrolled treatment of clients with ibogaine in the Netherlands, France, and Switzerland.6 According to Ken Alper, a world expert on this topic, “one important hazard in the use of iboga is polymorphic ventricular tachycardia, including torsades de pointes,” resulting in irregular ventricular fibrillation that could lead to death. But there are also many enthusiasts of the plant’s virtues, and a quick tour of the Internet can yield many reports of ibogaine cures for problematic drug use.

Treatment with ibogaine is not allowed in the US, the UK, France or Switzerland. Even so, it has been used illegally in treatments in hotel rooms and apartments. In Panama, the institution founded by Lotsof charges from USD 8,000 to USD 20,000 for the treatment; in Italy and Costa Rica, the cost is USD 2,500, and in North America it averages between USD 3,500 and USD 6,500. The cost in Thailand is cheaper, usually a few thousand dollars, not including airfare.7 There has been an attempt in Israel to study iboga for use in the treatment of “post-war syndrome” affecting soldiers, among other widely dispersed research projects popping up around the globe.

According to Antonio Bianchi, Italian physician and toxicologist with a research specialty in natural products, ibogaine “acts on an incredible number of neuronal receptors. Its main characteristic is its action on the NMDA (N-methyl-D-aspartate) s. These receptors are mainly found in two areas: the hippocampus, which controls the memory and memories, and proprioceptive sensitivity, responsible for the sensation we have of our physical body.” If these receptors are blocked, the person builds up an image of “the self” which is not related to the physical self; that is, it is outside the body. This would be the neurophysiological mechanism of “astral travel,” the meeting point between native and scientific theory. In these circumstances, a person tends to build what is defined as a bird’s-eye image, i.e., the subject assumes a projection of himself from a position of being above,” says the doctor.

This feeling is not only caused by ibogaine. It can also be produced by ketamine, a dissociative anesthetic, or as the result of a shock, a deep meditation, or other impacts on the nervous system. Medicine has devoted increasing attention to a phenomenon known as “near death experiences,” experienced by people who have been close to death. There are multiple reports of a recurrence of this type of experience: the presence of an infinite light which is divinity itself, meetings with the dead, a panoramic view of the subject’s own past lives, and the presence of a guide or religious figure leading one through a tube or path to the light.

Scientifically, one explanation is that the brain, when subjected to enormous stress (such as a heart attack, for example) produces hallucinations, immediately rebuilding a fantastic ersatz world. Initiation with iboga is an experience of this kind. In fact, some of the Bwitists’ descriptions of the “world beyond” coincide with reports of people who have been near death. For the mystics, on the contrary, this is evidence that this world really exists, and that there is a continuation of life after death.

The Bwiti Prophecy
There is a Bwiti prophecy that appeared in the 1940s when French Catholic colonial missionaries aggressively attacked the Bwiti, which says that this religion would spread and unite all the Black people in the world. The Bwitists are, however, open to White people being initiated, and in recent years, many foreigners, especially from France, have undergone the experience.8 The healer Justine, however, remarked, “we’ve found that Europeans do not have the same organism as we do. So we make a more lightweight treatment; you can’t give them the same amount of eboka we give to an African. When we know the person has ‘travelled,’ we stop.”

I attended a prière and took a spoonful of iboga. The effect was very strong and lasted 24 hours. I can’t say I understood very much; I thought the ritual was very tiring. My feeling was that the Fang are right; iboga is something that has little to do with this world, and has more to do with the world of the dead. I was enormously curious but afraid of undergoing the initiation. Africa, on its own, was already quite intoxicating.

Postscript
Shortly after finishing this text, my travelling companion discovered that he had malaria. I was stuck for six days in the north of the country, in a Muslim region (I discovered that a man in this region can have a maximum of four wives). Savannah: hot and very dusty. The various medicines did not work. The treatment is continuing. L’Afrique c’est dure.

Notes
1          The spelling varies by region: eboga, eboka, iboga, liboka, ébogé. There are also names like mdombo, bondo, dibuyi, among others. Iboga is the most widespread term.
2          Editorial note from 2014: see: K.R. Alper et al. The ibogaine medical subculture, Journal of Ethnopharmacology 115 (2008), 9-24.
3          Editorial note from 2014: See: Samorini, Giorgio (2005). Buiti: religião enteogênica africana. In: Beatriz Labate and Sandra Goulart, O uso ritual das plantas de poder. Campinas, Brazil: Mercado de Letras.
4          Editorial note from 2014: Howard Lotsof passed away in 2010.
5          Bouiti is the French spelling, in English Bwiti, and in Portuguese Buiti.
6          Editorial note from 2014: See: Alper, K. R., Stajić, M. & Gill, J. R. (2012), Fatalities temporally associated with the ingestion of ibogaine. Journal of Forensic Sciences, 57, 398-412. doi: 10.1111/j.1556-4029.2011.02008.x; see also Brown, T. K. (2013), The use of ibogaine in the treatment of substance dependence, Current Drug Abuse Reviews 6, 3-13.
7          Editorial note from 2014: Thomas K. Brown, personal communication, May 2014.
8          Editorial note from 2014. See: Chabloz, N. (2011), Voyages salvateurs. Anthropologie du tourisme “solidaire” et “chamanique” (Burkina Faso, Gabon). [Trips of Salvation. Anthropology of “Fair” and “Shamanic” Tourism (Burkina Faso, Gabon)]. PhD dissertation in social anthropology, École des Hautes Études en Sciences Sociales. Paris.

Yaoundé, February 2001

Bia Labate, PhD is an anthropologist and researcher with NEIP, the Interdisciplinary Group for Psychoactive Studies (www.neip.info)

Original Portuguese version published on TerraMistica.com.br during author’s travels in Africa.

Edited English-language translation with the addition of editorial footnotes published on Erowid.

© Bia Labate

By Bia Labate

Afrique
I landed at the airport in Yaoundé, capital of Cameroon, with the aim of collecting data on a mysterious African root to which powerful therapeutic properties are attributed. The first sensation, the hot and clammy air, is familiar. The pagne, a traditional African garment, makes us feel for a moment that we are back in Salvador, Brazil; but we soon realize that it is not quite “the same thing.” In just a few hours, all our conceptual references have disappeared. To an outsider, there is no coherence or aesthetic order. There are no streets or addresses; traffic is every man for himself. Music 24 hours a day. Men innocently holding hands in the streets. When you walk around the “city,” people stare, make comments, and touch you. As a white person, you want to be invisible.

It’s difficult not to be shocked by Africa, to be immune. Suddenly, it seems that we are waking from a dream: There, before our eyes, a whole continent is throbbing and spreading out its enormous natural wealth and economic poverty. Amidst this scenario, there are thousands of beautiful, creative hairstyles, expressing the power of a people, bewitching and infecting the visitor with a strong sense of joy.

Iboga1
It was not difficult to find the plant. The active components are derived from the underground root of a plant that reaches 1.50 m in height and belongs to the Tabernanthe genus, which is made up of many different species, 650 of which have been identified in Central Africa. The one that has most interested Western medicine is Tabernanthe iboga, found mainly in the region of Cameroon, Gabon, the Central African Republic, the Congo, the Democratic Republic of Congo, Angola, and Equatorial Guinea. The shrub grows in tropical forest areas, swampy soils, or wet savannas. It blooms and produces fruit throughout the year. Its main alkaloid and active ingredient is ibogaine, which is extracted from the bark of the root, and represents 90% of the 30 alkaloids found in the roots of this species. Iboga is formally classified as part of the family of the hallucinogens, which include peyote, mushrooms, LSD and ayahuasca. Alper2 has claimed that its phenomenology is different from classic hallucinogens, and that serotonergic transmission, while generative of hallucinations, is not the cause of ibogaine’s action in opioid withdrawal attenuation.

It is believed that the Pygmies have used iboga since time immemorial. Up until today, these people have used it in rituals that Whites have rarely been permitted to attend. According to the writings of an expert on the plant, the Italian Giorgio Samorini, some species of animals, including mandrills and wild boar, feed on the roots of the iboga to obtain inebriating effects. There is a speculative theory that the Pygmies discovered the hallucinogenic properties of iboga by observing the curious behavior of these animals.3

Ibogaine was first isolated in 1901. It is reported that it was used in the West from the beginning of the century to treat flu, infectious diseases, neurasthenia, and sleep-related illnesses.

In 1962, Howard Lotsof,4 a young heroin-dependent man in search of a new drug experience, discovered iboga. After a trip lasting 36 hours, he said that he had completely lost his craving for heroin and felt no withdrawal symptoms. He gave the substance to seven friends who were also dependent on heroin, and in all cases, the result was the same. In 1983, Lotsof reported the anti-addictive properties of ibogaine, and in 1985, obtained four US patents for the treatment of addiction to opium, cocaine, amphetamines, ethanol, and nicotine. He founded the International Coalition for Addict Self Help (ICASH) and developed the Endabuse method, an experimental pharmacotherapy that makes use of ibogaine HCl, the soluble form of ibogaine. By administering a single dose, the effect of which lasts for two days, considerable or complete attenuation of withdrawal symptoms has been reported, allowing the patient to painlessly detox. There is also allegedly an absence or lessening of the desire to take drugs for some period of time afterward.

The Initiation Rituals of the Bwiti5 Tradition
Currently, iboga is used by traditional healers of the countries of the Congo Basin and the Bwiti religion in Equatorial Guinea, Cameroon, and especially in Gabon, where important members of the political and military hierarchies are congregants. They make use particularly of the bark of the root, but medicinal properties are also attributed to the leaves, the bark of the trunk, and the root itself. In Gabon, the bark of the root and the root are easily found in traditional pharmacies and markets in major cities. There also exists an NGO dedicated entirely to iboga (Association for Nature, Culture, Future: EBANDO). Some claim that, if current trends continue, the collection of wild specimens of the root is putting it at risk of extinction. Iboga may be used alone or in combination with other plants. It is used in the treatment of infertility, depression, snakebites, male impotence, female infertility, AIDS, and also as a stimulant and aphrodisiac. In the belief of local healers, it is also helps to combat “mystical diseases,” such as being possessed.

Tonye Mahop, a researcher at the Limbe Botanical Gardens, says, “there are a number of records of it curing cigarette dependency, mganga (marijuana) and fofo (a local alcohol concentrate made from palm wine) with iboga in the Bwiti rituals. The problem is that the informers do not tell how they prepare and use the plant, so that there is always a part of the knowledge that is kept secret.”

There are two types of Bwiti: the traditional, which rejects Christianity, and the syncretic, which is more widespread. The first is practiced by the Mitsogho, and the later by the Fang, both Bantu groups. It is likely that during the nineteenth century the Pygmies transmitted their knowledge to the Apindji, who in turn passed it on to the Mitsogho, both southern Gabon tribal groups. During the nineteenth century, these groups developed the cult of the dead, which characterizes the traditional Bwiti. The syncretic Bwiti or Fang was formulated at the time of the First World War. This form is the product of traditional Bwiti influences; the traditional ancestor worship of the Fang; the Bieri, who used a different hallucinogenic plant; and Christian evangelization, especially Catholic. Currently, there are at least nine branches of Bwiti. There is also another cult that uses iboga, Abri, which has been little studied. This cult is controlled by women and treats diseases by using medicinal plants and iboga.

Abada Mangue Clavina is President of the Bombo Ima et Bandeei Association (ASSOKOBINAC) of Cameroon and the leader of the Bwiti Dissumba Mono Bata Church in Yaoundé, whose base is his nuclear family consisting of his two wives and 10 children. There are prière  (prayer) sessions every Saturday. He says that there is a specific iboga treatment for problematic drug use that lasts two or three days, depending on the patient and severity of the problem. Two, three, or four teaspoons (4-8 grams) of powdered, scraped, and chopped root bark are administered. “Iboga purifies the blood. We have been successful in 100% of the cases.” The most difficult cases may require an initiation, which costs 200,000 African francs (CFA) (about USD 260.00 in 2011) as opposed to the 50,000 (USD 66.00) that ordinary treatment will cost.

The initiation lasts three days. At the beginning, the candidate confesses all his sins and takes a ritual bath. The climactic moment in the life of the Bwitist is marked by the consumption, after fasting, of an enormous amount of eboka (up to 500 g) and ossoup, a kind of cold tea made from the root of the plant. A group follows the neophyte during the prière, where all sing, play music, and dance into the night.

The initiation ceremony aims at inducing a coma, but scholars have not yet been able to precisely time its duration. According to practitioners, at a certain moment the spirit leaves the body and travels to the level of creation, on the “other side”; in other words, it visits the world of the dead, where one can receive revelations, be healed, or communicate with one’s ancestors. The citar, the “sacred harp,” guides the journey and brings the spirit back to the body. After the ceremony, the subject, reborn with a new identity – that of Bandzi, “he who ate” – must report his visions and experiences in detail. The difference between the Bwiti ritual and that of other rites of passage traditionally studied by anthropologists is that, in this case, death might not be metaphorical or symbolic, but almost real, as it might take the subject to the absolute limit between life and death.

The healer Nanga Nga Owono Justine, initiated 25 years ago in the dissumba of the Bwiti branch, explains: “Eboka is a science that corrects. It is like a door that only opens when a person dies. Eboka has given Black people the chance to visit a place we go to when we die, but we go there before we die, and this is an opportunity to become transformed.” Her mother, the elderly Bilbang Nga Owono Christine, adds: “In order to become healed you have to be convinced, and you will heal yourself. You need the will, eboka, and faith in God, who is the master of everything.” Recalling her own initiation, when she had an “eye disease,” she said that “a star guided me to a hospital on the other side, where my eyes were operated. I saw my spirit leaving my body and the doctors operating me. I returned cured.”

Death may occur in the Bwiti initiation rituals. According to Calvin, this may be the result of several factors. One would be the incompetence or lack of ability of the guerriseur (healer). Another is that eboka cannot be given to someone who is physically too weak. Finally, “if the one undergoing the initiation is a witch or sorcerer, during the trip to the stars, the spirit will want to travel to the zone of darkness and may lose its way and not return, causing the death of the physical body.” The Fang know an antidote, a leaf called ebebing, which they affirm can reverse the effect of the eboka.

The Scientific Version
The scientific literature on the subject is controversial. It is known that ibogaine produces ataxia (loss of body balance), tremors, and lowered body temperature, slowing of heart rate (bradycardia) and lowered blood pressure. Studies in rats have shown that ibogaine in a dosage of 100 mg/kg given intraperitoneally (i.p.) is neurotoxic; a dose considerably higher than the 40 mg/kg i.p. typically used in studies on drug self-administration and withdrawal (the dose in Lotsof’s treatment protocol is usually 15 to 25 mg/kg in humans). It is different from other drugs in that it acts directly to reduce craving and withdrawal by an unknown mechanism in the human body. However, its exact degree of effectiveness is unknown: There are cases of recovery but also of failure. There is no scientific study that proves that ibogaine “cures addiction” – however complicated this notion is–only substantial anecdotal evidence. Similar to reports of death in the Bwiti initiation rites using iboga, there have also been 19 reported deaths as a result of the uncontrolled treatment of clients with ibogaine in the Netherlands, France, and Switzerland.6 According to Ken Alper, a world expert on this topic, “one important hazard in the use of iboga is polymorphic ventricular tachycardia, including torsades de pointes,” resulting in irregular ventricular fibrillation that could lead to death. But there are also many enthusiasts of the plant’s virtues, and a quick tour of the Internet can yield many reports of ibogaine cures for problematic drug use.

Treatment with ibogaine is not allowed in the US, the UK, France or Switzerland. Even so, it has been used illegally in treatments in hotel rooms and apartments. In Panama, the institution founded by Lotsof charges from USD 8,000 to USD 20,000 for the treatment; in Italy and Costa Rica, the cost is USD 2,500, and in North America it averages between USD 3,500 and USD 6,500. The cost in Thailand is cheaper, usually a few thousand dollars, not including airfare.7 There has been an attempt in Israel to study iboga for use in the treatment of “post-war syndrome” affecting soldiers, among other widely dispersed research projects popping up around the globe.

According to Antonio Bianchi, Italian physician and toxicologist with a research specialty in natural products, ibogaine “acts on an incredible number of neuronal receptors. Its main characteristic is its action on the NMDA (N-methyl-D-aspartate) s. These receptors are mainly found in two areas: the hippocampus, which controls the memory and memories, and proprioceptive sensitivity, responsible for the sensation we have of our physical body.” If these receptors are blocked, the person builds up an image of “the self” which is not related to the physical self; that is, it is outside the body. This would be the neurophysiological mechanism of “astral travel,” the meeting point between native and scientific theory. In these circumstances, a person tends to build what is defined as a bird’s-eye image, i.e., the subject assumes a projection of himself from a position of being above,” says the doctor.

This feeling is not only caused by ibogaine. It can also be produced by ketamine, a dissociative anesthetic, or as the result of a shock, a deep meditation, or other impacts on the nervous system. Medicine has devoted increasing attention to a phenomenon known as “near death experiences,” experienced by people who have been close to death. There are multiple reports of a recurrence of this type of experience: the presence of an infinite light which is divinity itself, meetings with the dead, a panoramic view of the subject’s own past lives, and the presence of a guide or religious figure leading one through a tube or path to the light.

Scientifically, one explanation is that the brain, when subjected to enormous stress (such as a heart attack, for example) produces hallucinations, immediately rebuilding a fantastic ersatz world. Initiation with iboga is an experience of this kind. In fact, some of the Bwitists’ descriptions of the “world beyond” coincide with reports of people who have been near death. For the mystics, on the contrary, this is evidence that this world really exists, and that there is a continuation of life after death.

The Bwiti Prophecy
There is a Bwiti prophecy that appeared in the 1940s when French Catholic colonial missionaries aggressively attacked the Bwiti, which says that this religion would spread and unite all the Black people in the world. The Bwitists are, however, open to White people being initiated, and in recent years, many foreigners, especially from France, have undergone the experience.8 The healer Justine, however, remarked, “we’ve found that Europeans do not have the same organism as we do. So we make a more lightweight treatment; you can’t give them the same amount of eboka we give to an African. When we know the person has ‘travelled,’ we stop.”

I attended a prière and took a spoonful of iboga. The effect was very strong and lasted 24 hours. I can’t say I understood very much; I thought the ritual was very tiring. My feeling was that the Fang are right; iboga is something that has little to do with this world, and has more to do with the world of the dead. I was enormously curious but afraid of undergoing the initiation. Africa, on its own, was already quite intoxicating.

Postscript
Shortly after finishing this text, my travelling companion discovered that he had malaria. I was stuck for six days in the north of the country, in a Muslim region (I discovered that a man in this region can have a maximum of four wives). Savannah: hot and very dusty. The various medicines did not work. The treatment is continuing. L’Afrique c’est dure.

Notes
1          The spelling varies by region: eboga, eboka, iboga, liboka, ébogé. There are also names like mdombo, bondo, dibuyi, among others. Iboga is the most widespread term.
2          Editorial note from 2014: see: K.R. Alper et al. The ibogaine medical subculture, Journal of Ethnopharmacology 115 (2008), 9-24.
3          Editorial note from 2014: See: Samorini, Giorgio (2005). Buiti: religião enteogênica africana. In: Beatriz Labate and Sandra Goulart, O uso ritual das plantas de poder. Campinas, Brazil: Mercado de Letras.
4          Editorial note from 2014: Howard Lotsof passed away in 2010.
5          Bouiti is the French spelling, in English Bwiti, and in Portuguese Buiti.
6          Editorial note from 2014: See: Alper, K. R., Stajić, M. & Gill, J. R. (2012), Fatalities temporally associated with the ingestion of ibogaine. Journal of Forensic Sciences, 57, 398-412. doi: 10.1111/j.1556-4029.2011.02008.x; see also Brown, T. K. (2013), The use of ibogaine in the treatment of substance dependence, Current Drug Abuse Reviews 6, 3-13.
7          Editorial note from 2014: Thomas K. Brown, personal communication, May 2014.
8          Editorial note from 2014. See: Chabloz, N. (2011), Voyages salvateurs. Anthropologie du tourisme “solidaire” et “chamanique” (Burkina Faso, Gabon). [Trips of Salvation. Anthropology of “Fair” and “Shamanic” Tourism (Burkina Faso, Gabon)]. PhD dissertation in social anthropology, École des Hautes Études en Sciences Sociales. Paris.

Yaoundé, February 2001

Bia Labate, PhD is an anthropologist and researcher with NEIP, the Interdisciplinary Group for Psychoactive Studies (www.neip.info)

Original Portuguese version published on TerraMistica.com.br during author’s travels in Africa.

Edited English-language translation with the addition of editorial footnotes published on Erowid.

© Bia Labate

Mind and Body are Mutually Independent

By Peter Meyer, MPhil

As is well-known a dualism of mind (thinking substance) and body (extended substance) was proposed by René Descartes in his Principia philosophiae (published in 1644), and became the basis of what is today known as the philosophical problem of the relation of mind to body.  Descartes’ dualism has been criticized by many philosophers. There are reasons to hold that it is mistaken (or at least a gross oversimplification), but in this essay that dualism is accepted (for the sake of argument) with the following clarifications:

Mind
 is synonymous with consciousness, which itself needs no definition because we all know it directly.  Much can be said about it, but it is indefinable and inexplicable, except insofar as neural correlates of consciousness can be ascertained by empirical experiment.  (These neural correlates are identified with consciousness by so-called Identity Theorists, a view which is erroneous but whose criticism need not detain us here.)

Body is synonymous with physical object, but in this context it means an organized system of closely-connected physical entities (molecules, tissues, etc., and non-biological systems such as computers) functioning in ways which may or may not be entirely understood (which is certainly the case for all biological organisms).

We are, of course, most familiar with the connection between mind and body in the case of our own minds and bodies.  Normally our mind is intimately connected with our body.  The connection is so close that some philosophers identify them (erroneously).  For example, a normal person needs only to will their arm to rise and it rises (although what, upon examination, the will is, or even if there is such a thing at all, is not entirely clear).  We appear to ourselves as bodies (somehow) conscious among many other bodies (organic and inorganic) comprising the physical world, that is, the world which we experience and know by means of our outer senses (mainly sight and touch, augmented by taste and smell).

When the biochemistry of the brain is altered by the introduction of certain chemical substances, this normal experience of an intimately-connected body and mind may be altered, in some cases very much so.  These chemical substances are among those classified as psychedelics, among which are the well-known LSD, psilocybin and mescaline, and the less well-known DMT, ketamine, ibogaine, 2C-B, etc.

Most philosophers of mind pay little or no attention to the known effects of psychedelics upon consciousness.  This may be explained by the effects of the so-called War on Drugs (promoted principally by the U.S. and to a lesser extent by other countries following its lead).  It may be that some (most?) philosophers are reluctant to discuss (in public) the well-known (although extremely diverse) effects of LSD and other psychedelics on consciousness because these substances are illegal and proscribed, and they do not wish to be seen as possibly condoning what is illegal. Or it may be that they are simply afraid to venture beyond normal consciousness. Whatever, the fact is that consciousness is consciousness in all its forms, not just in its normal form, that is, everyday consciousness, the sort you are aware of when on the job or eating dinner (when not under the influence of drugs such as alcohol and nicotine).  So philosophers who ignore forms of consciousness induced by the ingestion of psychedelics (either as personal experience or as reports by others) ignore a vast realm of empirical data which is very relevant to their implicitly stated intention to attempt to understand consciousness.

There are a large (and increasing) number of known psychedelics, and they have a huge diversity of effects upon the mind.  Of particular interest are those which induce (to some degree) a separation of mind and body.  These have been classified as dissociatives, the most well-known being ketamine, but there are others which may or may not be classified as dissociatives, in particular, DMT.  The effects of these, which we may call separative psychedelics, are well-documented in the psychedelic literature, which any philosopher may read if they care to (see especially the many trip reports at Erowid). DMT is an especially interesting substance, since it can induce complete loss of bodily awareness and its replacement by what appears as a totally alien dimension of consciousness.

As noted above, in normal consciousness (human and presumably animal consciousness) there is a very intimate relation between mind and body.  Under the influence of a separative psychedelic such as ketamine, awareness of the body is greatly lessened, and in its place there is awareness of something hard to describe but which is directly known to anyone who has used such a substance.  Intriguing (sometimes overwhelming) visual imagery is common (often complex, and which may change rapidly or slowly), normal concepts of space and time may be severely altered, strange and sometimes profound ideas may enter the mind, and there may even be an awareness (vague or clear) of other (‘higher’) intelligent entities, with whom communication may be attempted (if not wholly successfully).

Under the influence of a separative psychedelic it is not uncommon to come to believe that one is dying, or is about to die. (There may even be a ‘realistic’ awareness of undergoing some kind of orderly transition to a post-mortal state.)  This, of course, may lead to considerable anxiety.  The reason for this anxiety is based upon our usual understanding of death, which we have formed from seeing or hearing about dead bodies.  When a person dies, their body, which previously was an expression of their mind, with all its displays of emotion, intelligence (or lack of it), intention, relation to others, etc., ceases to be an expression of their mind, and becomes inert: the soul has fled.  If one loved that person then this is often a traumatic experience.  In any case, the event is not understood, and is usually feared.

When we witness the death of a person (although in modern Western society, wherein death is taboo, this rarely happens, though much simulated or fictional ‘death’ is shown to us from childhood via television) we see that the body suddenly ceases to function.  Under the influence of a separative psychedelic we lose (partially or wholly) awareness of our functioning body.  Our body continues to function normally (unless the chemical interferes with the biological functions needed to sustain life), it’s just that we no longer are intimately connected to it.  This absence of awareness leads us to believe that our body itself has ceased functioning, which is death, and so the fear associated with death arises in our mind.  A person who has had much experience with separative psychedelics may learn to control this fear, based on their knowledge that in past experiences of this sort they have never died, but have always eventually returned to normal consciousness (although there is always the lingering doubt: but this time?).

Even though awareness of the body may have (largely) disappeared, there remains awareness of something which is not the body (as said above, hard to describe).  This shows that body-awareness does not constitute the whole of possible consciousness.  I suggest that the extent of  non-body-awareness consciousness may be as great as the extent of our consciousness of the physical world, and that there is an oneiric world which may be as vast as the physical world (although as yet largely undiscovered, and certainly undiscovered by most people).  The term oneiric relates to dreams, but I suggest that this is an appropriate term for this (largely undiscovered) world because most people’s experience of the oneiric world is confined to their dreams.  But beyond dreaming are states of consciousness similar in nature but very different. Dreaming is like wading in the shallows at the seashore, and being conscious under the influence of a powerful psychedelic is like going way out and diving into the depths; but there’s no essential difference between the shallows and the depths. Our personal selves lie at the intersection of these two worlds, the physical and the oneiric, and we can experience both, sometimes at the same time.

As regards the title of this essay, it may be objected that the mind depends on the body, in the sense that without a functioning body (with, in the case of humans, a functioning brain) there can be no mind (no consciousness connected with that body).  This is simply a dogmatic assertion made by those philosophers who hold (erroneously) that only what is physical really exists (from which false assumption they draw the false conclusion that consciousness must somehow be something physical).  There is no convincing evidence to support this assertion; it is rather an act of faith.  The existence of neural activity which is correlated with some mental content does not prove identity, and those who emphasize this correlation ignore the much larger amount of (potential and reported) mental content which has no known (or even any plausibly likely) correlation with neural activity. Evidence which refutes the assertion of the dependence of mind on body is (as pointed out above) provided by the huge number of reports of psychedelic experience, especially that experience under the influence of separative psychedelics, wherein consciousness of the body may be lost but consciousness remains, and may be extremely rich in content.  Thus the available evidence supports the claim that mind is not dependent on body.

And, of course, body is not dependent on mind.  A computer is an organized system of closely-connected physical entities (atoms, molecules, crystals, gates, circuits, magnetic or other memory, etc.) but there is no mind connected with it.  (This is true also of any imaginable computer, because whatever can be assembled from parts cannot be a conscious being, since when, during the process of assembly, would consciousness arise?)  Thus the title of this essay: Mind and body are mutually independent.

© 2013 Peter Meyer

This article first appeared on 28 May 2013 on Peter Meyer’s website Serendipity. Published with permission.

Revision and Revisioning of Psychology

Legacy from Half a Century of Consciousness Research
By Stanislav Grof, MD

In this paper, Stanislav Grof summarizes his observations and experiences from more than half a century of research into an important subgroup of non-ordinary states for which he coined the nameholotropic; these findings seriously challenge the existing scientific paradigms. All these years, his primary interest has been to explore the healing, transformative, and evolutionary potential of non-ordinary states of consciousness and their great value as a source of new revolutionary data about consciousness, the human psyche, and the nature of reality.

In 1962, Thomas Kuhn, one of the most influential philosophers of the twentieth century, published his groundbreaking book The Structure of Scientific Revolutions (Kuhn 1962). On the basis of fifteen years of intensive study of the history of science, he was able to demonstrate that the development of knowledge about the universe in various scientific disciplines is not a process of gradual accumulation of data and formulation of ever more accurate theories, as usually assumed. Instead, it shows a clearly cyclical nature with specific stages and characteristic dynamics, which can be understood and even predicted.

The central concept of Kuhn’s theory, which makes this possible, is that of a paradigm. A paradigm can be defined as a constellation of beliefs, values, and techniques shared by the members of the community at a particular historical period. It governs the thinking and research activities of scientists until some of its basic assumptions are seriously challenged by new observations. This leads to a crisis and emergence of suggestions for radically new ways of viewing and interpreting the phenomena that the old paradigm is unable to explain. Eventually, one of these alternatives satisfies the necessary requirements to become the new paradigm that then dominates the thinking in the next period of the history of science.

The most famous historical examples of paradigm shifts have been the replacement of the Ptolemaic geocentric system by the heliocentric system of Copernicus, Kepler, and Galileo, the overthrow of Becher’s phlogiston theory in chemistry by Lavoisier and Dalton, and the conceptual cataclysms in physics in the first three decades of the twentieth century that undermined the hegemony of Newtonian physics and gave birth to theories of relativity and quantum physics. Paradigm shifts tend to come as a major surprise to mainstream academic community, since its members tend to mistake the leading paradigms for an accurate and definitive description of reality. Thus in 1900 shortly before the advent of quantum-relativistic physics, Lord Kelvin declared: “There is nothing new to be discovered in physics now. All that remains is more and more precise measurements.”

In the last five decades, various avenues of modern consciousness research have revealed a rich array of “anomalous” phenomena – experiences and observations that have undermined some of the generally accepted assertions of modern psychiatry, psychology, and psychotherapy concerning the nature and dimensions of the human psyche, the origins of emotional and psychosomatic disorders, and effective therapeutic mechanisms. Many of these observations are so radical that they question the basic metaphysical assumptions of materialistic science concerning the nature of reality and of human beings and the relationship between consciousness and matter. 

In this paper, I will summarize my observations and experiences from more than half a century of research into an important subgroup of non-ordinary states for which I coined the name holotropic; these findings seriously challenge the existing scientific paradigms. Before I address this topic, I would like to explain the term holotropic that I will be using throughout this article. All these years, my primary interest has been to explore the healing, transformative, and evolutionary potential of non-ordinary states of consciousness and their great value as a source of new revolutionary data about consciousness, the human psyche, and the nature of reality. 

From this perspective, the term “altered states of consciousness” (Tart 1969) commonly used by mainstream clinicians and theoreticians is not appropriate, because of its one-sided emphasis on the distortion or impairment of the “correct way” of experiencing oneself and the world. (in colloquial English and in veterinary jargon, the term “alter” is used to signify castration of family dogs and cats). Even the somewhat better term “non-ordinary states of consciousness” is too general, since it includes a wide range of conditions that are not relevant from the point of view of the focus of this paper. This includes trivial deliria caused by infectious diseases, abuse of alcohol, or circulatory and degenerative diseases of the brain. These alterations of consciousness are associated with disorientation, impairment of intellectual functions, and subsequent amnesia; they are clinically important, but lack therapeutic and heuristic potential. 

The term “holotropic” refers to a large subgroup of non-ordinary states of consciousness that are of great theoretical and practical importance. These are the states that novice shamans experience during their initiatory crises and in later life induce in their clients for therapeutic purposes. Ancient and native cultures have used these states in rites of passage and in their healing ceremonies. They were described by mystics of all ages and initiates in the ancient mysteries of death and rebirth. Procedures inducing these states were also developed and used in the context of the great religions of the world – Hinduism, Buddhism, Jainism, Taoism, Islam, Judaism, Zoroastrianism, and Christianity.

The importance of holotropic states of consciousness for ancient and aboriginal cultures is reflected in the amount of time and energy that the members of these human groups dedicated to the development oftechnologies of the sacred, various procedures capable of inducing them for ritual and spiritual purposes. These methods combine in various ways drumming and other forms of percussion, music, chanting, rhythmic dancing, changes of breathing, and cultivation of special forms of awareness. Extended social and sensory isolation, such as stay in a cave, desert, arctic ice, or in high mountains, also play an important role as means of inducing this category of non-ordinary states. Extreme physiological interventions used for this purpose include fasting, sleep deprivation, dehydration, use of powerful laxatives and purgatives, and even infliction of severe pain, body mutilation, and massive bloodletting. By far the most effective tool for inducing healing and transformative non-ordinary states has been ritual use of psychedelic plants.

When I recognized the unique nature of this category of non-ordinary states of consciousness, I found it difficult to believe that contemporary psychiatry does not have a specific category and term for these theoretically and practically important experiences. Because I felt strongly that they deserve to be distinguished from “altered states of consciousness” and not be seen as manifestations of serious mental diseases, I started referring to them as holotropic. This composite word means literally “oriented toward wholeness” or “moving toward wholeness” (from the Greek holos = whole and trepo/trepein = moving toward or in the direction of something). The word holotropic is a neologism, but it is related to a commonly used term heliotropism – the property of plants to always move in the direction of the sun.

The name holotropic suggests something that might come as a surprise to an average Westerner – that in our everyday state of consciousness we identify with only a small fraction of who we really are and do not experience the full extent of our being. Holotropic states of consciousness have the potential to help us recognize that we are not “skin-encapsulated egos” – as British philosopher and writer Alan Watts called it – and that, in the last analysis, we are commensurate with the cosmic creative principle itself. Or that – using the statement by Pierre Teilhard de Chardin, French paleontologist and philosopher – “we are not human beings having spiritual experiences, we are spiritual beings having human experiences” (Teilhard de Chardin 1975).

This astonishing idea is not new. In the ancient Indian Upanishads, the answer to the question: “Who am I?” is “Tat tvam asi.” This succinct Sanskrit sentence means literally: “Thou art That,” where “That” refers to Godhead. It suggests that we are not “namarupa” – name and form (body/ego), but that our deepest identity is with a divine spark in our innermost being (Atman) which is ultimately identical with the supreme universal principle that creates the universe (Brahman). And Hinduism is not the only religion that has made this discovery. The revelation concerning the identity of the individual with the divine is the ultimate secret that lies at the mystical core of all great spiritual traditions. The name for this principle could thus be the Tao, Buddha, Shiva (of Kashmir Shaivism), Cosmic Christ, Pleroma, Allah, and many others. Holotropic experiences have the potential to help us discover our true identity and our cosmic status (Grof 1998). Sometimes this happens in small increments, other times in the form of major breakthroughs. 

Psychedelic research and the development of intensive experiential techniques of psychotherapy in the second half of the twentieth century moved holotropic states from the world of healers of ancient and preliterate cultures into modern psychiatry and psychotherapy. Therapists who were open to these techniques and used them in their practice were able to confirm the extraordinary healing potential of holotropic states and discovered their value as goldmines of revolutionary new information about consciousness, the human psyche, and the nature of reality. I became aware of the remarkable properties of holotropic states in 1956 when I volunteered as a beginning psychiatrist for an experiment with LSD-25. During this experiment, in which the pharmacological effect of LSD was combined with exposure to powerful stroboscopic light (referred to as “driving” or “entraining” of the brainwaves), I had an overwhelming experience of cosmic consciousness (Grof 2006).

This experience inspired in me a lifelong interest in holotropic states; research of these states has become my passion, profession, and vocation. Since that time, most of my clinical and research activities have consisted of systematic exploration of the therapeutic, transformative, heuristic, and evolutionary potential of these states. The five decades that I have dedicated to consciousness research have been for me an extraordinary adventure of discovery and self-discovery. I spent approximately half of this time conducting psychotherapy with psychedelic substances, first in Czechoslovakia in the Psychiatric Research Institute in Prague and then in the United States, at the Maryland Psychiatric Research Center in Baltimore, where I participated in the last surviving American psychedelic research program. Since 1975, my wife Christina and I have worked with Holotropic Breathwork, a powerful method of therapy and self-exploration that we jointly developed at the Esalen Institute in Big Sur, California. Over the years, we have also supported many people undergoing spontaneous episodes of non-ordinary states of consciousness – psychospiritual crises or “spiritual emergencies,” as Christina and I call them (Grof and Grof 1989, Grof and Grof 1991).

In psychedelic therapy, holotropic states are brought about by administration of mind-altering substances, such as LSD, psilocybin, mescaline, and tryptamine or amphetamine derivatives. In holotropic breathwork, consciousness is changed by a combination of faster breathing, evocative music, and energy-releasing bodywork. In spiritual emergencies, holotropic states occur spontaneously, in the middle of everyday life, and their cause is usually unknown. If they are correctly understood and supported, these episodes have an extraordinary healing, transformative, and even evolutionary potential.

In addition, I have been tangentially involved in many disciplines that are, more or less directly, related to holotropic states of consciousness. I have spent much time exchanging information with anthropologists and have participated in sacred ceremonies of native cultures in different parts of the world with and without the ingestion of psychedelic plants, such as peyote, ayahuasca, and psilocybe mushrooms. This involved contact with various North American, Mexican, South American, and African shamans and healers. I have also had extensive contact with representatives of various spiritual disciplines, including Vipassana, Zen, and Vajrayana Buddhism, Siddha Yoga, Tantra, and the Christian Benedictine order.

Another area that has received much of my attention has been thanatology, the young discipline studying near-death experiences and the psychological and spiritual aspects of death and dying. In the late 1960s and early 1970s I participated in a large research project studying the effects of psychedelic therapy for individuals dying of cancer. I also I have had the privilege of personal acquaintance and experience with some of the great psychics and parapsychologists of our era, pioneers of laboratory consciousness research, and therapists who had developed and practiced powerful forms of experiential therapy that induce holotropic states of consciousness.

My initial encounter with holotropic states was very difficult and intellectually, as well as emotionally, challenging. In the early years of my laboratory and clinical research with psychedelics, I was daily bombarded with experiences and observations, for which my medical and psychiatric training had not prepared me. As a matter of fact, I was experiencing and seeing things, which – in the context of the scientific worldview I obtained during my medical training – were considered impossible and were not supposed to happen. And yet, those obviously impossible things were happening all the time. I have described these “anomalous phenomena” in my articles and books (Grof 2000, 2006).

In the late 1990s, I received a phone call from Jane Bunker, my editor at State University New York (SUNY) Press that had published many of my books. She asked me if I would consider writing a book that would summarize the observations from my research in one volume that would serve as an introduction to my already published books. She also asked if I could specifically focus on all the experiences and observations from my research that current scientific theories cannot explain and suggest the revisions in our thinking that would be necessary to account for these revolutionary findings. This was a “tall order”, but also a great opportunity. My seventieth birthday was rapidly approaching and a new generation of facilitators was conducting our Holotropic Breathwork training all over the world. We needed a manual covering the material that was taught in our training modules. And here was an offer to provide it for us.

The result of this exchange was a book with a deliberately provocative title: “Psychology of the Future.” The radical revisions in our understanding of consciousness and the human psyche in health and disease that I suggested in this work fall into the following categories:

1. The Nature of Consciousness and Its Relationship to Matter
2. Cartography of the Human Psyche
3. Architecture of Emotional and Psychosomatic Disorders
4. Effective Therapeutic Mechanisms
5. Strategy of Psychotherapy and Self-Exploration
6. The Role of Spirituality in Human Life
7. The Importance of Archetypal Astrology for Psychology

In my opinion, these are the areas that require drastic changes in our thinking. Without them the understanding and treatment of psychogenic emotional and psychosomatic disorders and their therapy will remain superficial, unsatisfactory, and incomplete. Psychiatry and psychology will lack genuine comprehension of the nature and origin of spirituality and of the important role that it plays in the human psyche and in the universal scheme of things. These revisions are therefore essential for understanding the ritual, spiritual, and religious history of humanity – shamanism, rites of passage, the ancient mysteries of death and rebirth, and the great religions of the world. Without these radical changes in our thinking, potentially healing and heuristically invaluable experiences (“spiritual emergencies”) will be misdiagnosed as psychotic and treated by suppressive medication. In addition, a large array of the experiences and observations from the research of holotropic states will remain mystifying “anomalous phenomena”, events that according to the current scientific paradigms do not or should not occur. It will also be difficult for mental health professionals to accept the therapeutic power of psychedelic substances, mediated by experiences that are currently seen as psychotic – as indicated by such terms as experimental psychoses, psychotomimetics, or hallucinogens – commonly used by mainstream clinicians and academicians – rather than germane expressions of the deep dynamics of the psyche.

Considering my own initial resistance to the bewildering experiences and observations from the research of holotropic states, as well as phenomena associated with them (such as astonishing synchronicities), it will not surprise me if the above suggestions encounter strong resistance in the academic community. This is understandable, considering the scope and radical nature of the necessary conceptual revisions. There is a strong tendency in mainstream academic and clinical circles to “confuse map and territory” and consider current theories concerning consciousness and the human psyche in health and disease to be a definitive and accurate description of reality (Bateson 1972). We are not talking here about a minor patchwork, technically called “ad hoc hypotheses,” but a major fundamental overhaul. The resulting conceptual cataclysm would be comparable in its nature and scope to the revolution that physicists had to face in the first three decades of the twentieth century when they had to move from Newtonian to quantum-relativistic physics. And, in a sense, it would represent a logical completion of the radical changes in understanding of the material world that have already happened in physics.

In the history of science, individuals who suggested such far-reaching changes in the dominant paradigm have not enjoyed very enthusiastic reception; their ideas were initially dismissed as products of ignorance, poor judgment, bad science, fraud, or even insanity. I am now in the ninth decade of my life; this is the time when researchers often try to review their professional career and outline the conclusions at which they have arrived. More than half a century of research of holotropic states – my own, as well as that of many of my transpersonally-oriented colleagues – has amassed so much supportive evidence for a radically new understanding of consciousness and of the human psyche that I am willing to take my chance and describe this new vision in its entirety, fully aware of its controversial nature. The fact that it challenges the most fundamental metaphysical assumptions of materialistic science should not be a sufficient reason for rejecting it. Whether it will be refuted or accepted should be determined by unbiased future research of holotropic states.

1. The Nature of Consciousness and its Relationship to Matter

According to the current scientific worldview, consciousness is an epiphenomenon of material processes; it allegedly emerges out of the complexity of the neurophysiological processes in the brain. This thesis is presented with great authority as an obvious fact that has been proven beyond any reasonable doubt. However, if we subject it to closer scrutiny, we discover that it is a basic metaphysical assumption that is not supported by facts and actually contradicts the findings of modern consciousness research.

We have ample clinical and experimental evidence showing deep correlations between the anatomy, physiology, and biochemistry of the brain, on the one hand, and states of consciousness, on the other. However, none of these findings proves unequivocally that consciousness is actually generated by the brain. Even sophisticated theories based on advanced research of the brain, such as Stuart Hameroff’s suggestion that the solution of the problem of consciousness might lie in understanding the quantum process in the microtubules of brain cells on the molecular and supramolecular level (Hameroff 1987), falls painfully short of bridging the formidable gap between matter and consciousness and illuminating how material processes could generate consciousness.

The origin of consciousness from matter is simply assumed as an obvious and self-evident fact based on the metaphysical assumption of the primacy of matter in the universe. In fact, in the entire history of science, nobody has ever offered a plausible explanation how consciousness could be generated by material processes, or even suggested a viable approach to the problem. We can use here as illustration the book by Francis Crick The Astonishing Hypothesis: The Scientific Search for the Soul; its jacket carried a very exciting promise: “Nobel Prize-winning Scientist Explains Consciousness.”

Crick’s “astonishing hypothesis” was succinctly stated at the beginning of his book: “You, your joys and your sorrows, your memories and your ambitions, your sense of personal identity and free will, are in fact no more than the behavior of a vast assembly of nerve cells and their associated molecules. Who you are is nothing but a pack of neurons.” At the beginning of his book, “to simplify the problem of consciousness,” Crick narrows it to the problem of optical perception. He presents impressive experimental evidence showing that visual perception is associated with distinct physiological, biochemical, and electrical processes in the optical system from the retina through the optical tract to the suboccipital cortex. And there the discussion ends as if the problem of consciousness had been satisfactorily solved.

In reality, this is where the problem begins. What is it that is capable of transforming biochemical and electric processes in the brain into a conscious experience of a reasonable facsimile of the object we are observing, in full color, and project it into three-dimensional space? The formidable problem of the relationship between phenomena – things as we perceive them – and noumena – things as they truly are in themselves (Dinge an sich) was clearly articulated by Immanuel Kant (Kant 1999). Scientists focus their efforts on the aspect of the problem where they can find answers – the material processes in the brain. The much more mysterious problem – how physical processes in the brain generate consciousness – does not receive any attention, because it is incomprehensible and cannot be solved.

The attitude that Western science has adopted in regard to this issue resembles the famous Sufi story. On a dark night, a man is crawling on his knees under a candelabra lamp. Another man sees him and asks: “What are you doing? Are you looking for something?” The man answers that he is searching for a lost key and the newcomer offers to help. After some time of unsuccessful joint effort, the helper is confused and feels the need for clarification. “I don’t see anything! Are you sure you lost it here?” he asks. The owner of the lost key shakes his head; he points his finger to a dark area outside of the circle illuminated by the lamp and replies: “Not here, over there!” The helper is puzzled and inquires further: “So why are we looking for it here and not over there?” “Because it is light here and we can see. Over there it’s dark, we would not have a chance!”

In a similar way, materialistic scientists have systematically avoided the problem of the origin of consciousness, because this riddle cannot be solved within the context of their conceptual framework. The idea that consciousness is a product of the brain naturally is not completely arbitrary. Its proponents usually refer to a vast body of very specific clinical observations from neurology, neurosurgery, and psychiatry, to support their position. The evidence for close correlations between the anatomy, neurophysiology, and biochemistry of the brain, and consciousness is unquestionable and overwhelming. What is problematic is not the nature of the presented evidence but the conclusions that are drawn from these observations. In formal logic, this type of fallacy is called non sequitur – an argument in which its conclusion does not follow from its premises. While the evidence clearly shows that consciousness is closely connected with the neurophysiological and biochemical processes in the brain, it has very little bearing on the nature and origin of consciousness.

This can be illustrated by looking at the relationship between the TV set and the television program. The situation here is much clearer, since it involves a system that is human-made and its operation is well known. The final reception of the television program, the quality of the picture and of the sound, depends in a very critical way on proper functioning of the TV set and on the integrity of its components. Malfunctioning of its various parts results in very distinct and specific changes of the quality of the program. Some of them lead to distortions of form, color, or sound, others to interference between the channels, etc. Like the neurologist who uses changes in consciousness as a diagnostic tool, a television mechanic can infer from the nature of these anomalies which parts of the set and which specific components are malfunctioning. When the problem is identified, repairing or replacing these elements will correct the distortions.

Since we know the basic principles of the television technology, it is clear to us that the set simply mediates the program and that it does not generate it. We would laugh at somebody who would try to examine and scrutinize all the transistors, relays, and circuits of the TV set and analyze all its wires in an attempt to figure out how it creates the programs. Even if we carry this misguided effort to the molecular, atomic, or subatomic level, we will have absolutely no clue why, at a particular time, a Mickey Mouse cartoon, a Star Trek sequence, or a Hollywood classic appear on the screen. The fact that there is such a close correlation between the functioning of the TV set and the quality of the program does not necessarily mean that the entire secret of the program is in the set itself. Yet this is exactly the kind of conclusion that traditional materialistic science drew from comparable data about the brain and its relation to consciousness.

There actually exists ample evidence suggesting exactly the opposite, namely that consciousness can under certain circumstances operate independently of its material substrate and can perform functions that reach far beyond the capacities of the brain. This is most clearly illustrated by the existence of out-of-body experiences (OOBEs). These can occur spontaneously, or in a variety of facilitating situations that include shamanic trance, psychedelic sessions, spiritual practice, hypnosis, experiential psychotherapy, and particularly near-death experiences (NDEs). In all these situations consciousness can separate from the body and maintain its sensory capacity, while moving freely to various close and remote locations. Of particular interest are veridical OOBEs, where independent verification proves the accuracy of perception of the environment. In near-death situations, veridical OOBEs can occur even in people who are congenitally blind for organic reasons (Ring and Valarino 1999, Ring and Cooper 1998). There are many other types of transpersonal phenomena that can mediate accurate information about various aspects of the universe that had not been previously received and recorded in the brain (Grof 2000).

Materialistic science has not been able to produce any convincing evidence that consciousness is a product of the neurophysiological processes in the brain. It has been able to maintain its present position only by ignoring, misinterpreting, and even ridiculing a vast body of observations indicating that con­sciousness can exist and function independently of the body and of the physical senses. This evidence comes from parapsychology, anthropology, LSD research, experiential psychotherapy, thanatology, and the study of spontaneously occurring holotropic states of consciousness (“spiritual emergencies”). All these disciplines have amassed impressive data demonstrating clearly that human consciousness is capable of doing many things that the brain (as understood by mainstream science) could not possibly do and that it is a primary and further irreducible aspect of existence – an equal partner of matter or possibly superordinated to it.

2. Cartography of the Human Psyche

Traditional academic psychiatry and psychology use a model of the human psyche that is limited to postnatal biography and to the individual unconscious as described by Sigmund Freud. According to Freud, our psychological history begins after we are born; the newborn is a tabula rasa, a clean slate. Our psychological functioning is determined by an interplay between biological instincts and influences that have shaped our life since we came into this world – the quality of nursing, the nature of toilet training, various psychosexual traumas, development of the superego, our reaction to the Oedipal triangle, and conflicts and traumatic events in later life.

The Freudian individual unconscious is also essentially a derivative of our postnatal history; it is a repository of what we have forgotten, rejected as unacceptable, and repressed. This underworld of the psyche (the idas Freud called it) is a realm dominated by primitive instinctual forces. Freud described the relationship between the conscious psyche and the unconscious using his famous image of the submerged iceberg. What we thought to be the totality of the psyche is just a small part of it, like the section of the iceberg showing above the surface. Psychoanalysis discovered that a much larger part of the psyche, comparable to the submerged part of the iceberg, is unconscious and, unbeknown to us, governs our thought processes and behavior.

Later contributions to dynamic psychotherapy added to etiological factors problems in the development of object relationships and interpersonal dynamics in the nuclear family (Black and Black 1974, 1979, Sullivan 1953, Satir 1983, Bateson et al. 1956), but shared with Freudian psychoanalysis the exclusive emphasis on postnatal life. Who we become and how we psychologically function is determined by what happened to us after we were born. In the work with holotropic states of consciousness induced by psychedelics and various non-drug means, as well as those occurring spontaneously, this model proves to be painfully inadequate. To account for all the phenomena occurring in these states, we must drastically revise our understanding of the dimensions of the human psyche. Besides the postnatal biographical level that it shares with traditional psychology, the new expanded cartography includes two additional large domains.

The first of these domains can be referred to as perinatal, because of its close connection with the trauma of biological birth. This region of the unconscious contains the memories of what the fetus experienced in the consecutive stages of the birth process, including all the emotions and physical sensations involved. These memories form four distinct experiential clusters, each of which is related to one of the stages of childbirth. I have coined for them the term Basic Perinatal Matrices (BPM I-IV).

BPM I consists of memories of the advanced prenatal state just before the onset of the delivery. BPM II is related to the first stage of the birth process when the uterus contracts, but the cervix is not yet open. BPM III reflects the struggle to be born after the uterine cervix dilates. And finally, BPM IV holds the memory of emerging into the world, the birth itself. The content of these matrices is not limited to fetal memories; each of them also represents a selective opening into the areas of the historical and archetypal collective unconscious, which contain motifs of similar experiential quality. Detailed description of the phenomenology and dynamics of perinatal matrices can be found in my various publications (Grof 1975, 2000).

The official position of academic psychiatry is that biological birth is not recorded in memory and does not constitute a psychotrauma. The usual reason for denying the possibility of birth memory is that the cerebral cortex of the newborn is not mature enough to mediate experiencing and recording of this event. More specifically, the cortical neurons are not yet “myelinized”- this means not yet completely covered with protective sheaths of a fatty substance called myelin. Surprisingly, the same argument is not used to deny the existence and importance of memories from the time of nursing, a period that immediately follows birth. The psychological significance of the experiences in the oral period and even “bonding” – the exchange of looks and physical contact between the mother and child immediately after birth – is generally recognized and acknowledged by mainstream obstetricians, pediatricians, and child psychiatrists, (Klaus, Kennell, and Klaus 1995, Kennel and Klaus 1998).

The myelinization argument makes no sense and is in conflict with scientific evidence of various kinds. It is well known that memory exists in organisms that do not have a cerebral cortex at all. In 2001, American neuroscientist of Austrian origin, Erik Kandel, received a Nobel Prize in physiology for his research of memory mechanisms of the sea slug Aplysia, an organism incomparably more primitive than the newborn child. The assertion that the newborn is not aware of being born and is not capable to form a memory of this event is also in sharp conflict with extensive fetal research showing the extreme sensitivity of the fetus already in the prenatal stage (Tomatis 1991, Whitwell 1999). In view of this evidence, the only way to understand the position of mainstream professionals is to attribute it to psychological repression and resistance in regard to the terrifying memory of biological birth.

The second transbiographical domain of the new cartography can best be called transpersonal, because it includes a rich array of experiences in which consciousness transcends the boundaries of the body/ego and the usual limitations of linear time and three-dimensional space. This results in experiential identification with other people, groups of people, other life forms, and even elements of the inorganic world. Transcendence of time provides experiential access to ancestral, racial, collective, phylogenetic, and karmic memories. Yet another category of transpersonal experiences can take us into the realm of the collective unconscious that the Swiss psychiatrist C.G. Jung called archetypal. This region harbors mythological figures, themes, and realms of all the cultures and ages, even those of which we have no intellectual knowledge (Jung 1959).

In its farthest reaches, individual consciousness can identify with the Universal Mind or Cosmic Consciousness, the creative principle of the universe. Probably the most profound experience available in holotropic states is identification with the Supracosmic and Metacosmic Void, primordial Emptiness and Nothingness that is conscious of itself. The Void has a paradoxical nature; it is a vacuum, because it is devoid of any concrete forms, but it is also a plenum, since it seems to contain all of creation in a potential form.

The classification of transpersonal experiences I have described in my books is strictly phenomenological and not hierarchical as it is presented in ancient Hindu and Buddhist literature and in the writings of Ken Wilber based on these sources; it does not specify the levels of consciousness on which they occur. However, it is not difficult to arrange transpersonal experiences in my classification in such a way that they closely parallel Wilber’s description of the levels of spiritual evolution (Wilber 1980). Constructing his map of psychospiritual development, Wilber used material from ancient spiritual literature, primarily from Vedanta Hinduism and both Theravada and Mahayana Buddhism. My own data are drawn from clinical observations in contemporary populations in a number of European countries, North and South America, and Australia, complemented by some limited experience with Japanese and East Indian experiential groups.

This research has provided empirical evidence for the existence of most of the experiences included in Wilber’s developmental scheme. It has also shown that the descriptions in ancient spiritual sources that Wilber refers to are still to a great extent relevant for modern humanity. However, examples that Wilber uses for various levels of psychospiritual development are rather scanty and incomplete; incorporating the observations from the study of holotropic states into his scheme requires some important additions and adjustments.

Wilber’s scheme of the post-centauric spiritual domain includes the lower and higher subtle level, lower and higher causal level, and the level of the Ultimate or Absolute. According to him, the low subtle, orastral-psychic, level of consciousness is characterized by a degree of differentiation of consciousness from the mind and body, which goes beyond that achieved on the level of the centaur. The astral level, in Wilber’s own words, “includes, basically, out-of-body experiences, certain occult knowledge, the auras, true magic, ‘astral travel,’ and so on.” Ken’s description of the psychic level includes various ‘psi’ phenomena: ESP, precognition, clairvoyance, psychokinesis, and others. He also refers in this connection to Patanjali’s Sutras that include on the subtle level all the paranormal powers, mind-over-matter phenomena, or siddhis (Patanjali 1990). In the higher subtle realm, consciousness differentiates itself completely from the ordinary mind and becomes what can be called the ‘overself’ or ‘overmind.’ Wilber places in this region high religious intuition and inspiration, visions of divine light, audible illuminations, and higher presences – spiritual guides, angelic beings, ishtadevas, Dhyani-Buddhas, and God’s archetypes, which he sees as high archetypal forms of our own being.

Like the subtle level, the causal level can be subdivided into lower and higher. Wilber points out that the lower causal realm is manifested in a state of consciousness known as savikalpa samadhi, the experience of final God, the ground, essence, and source of all the archetypal and lesser-god manifestations encountered in the subtle realms. The higher causal realm then involves a “total and utter transcendence and release into Formless Consciousness, Boundless Radiance.” Wilber refers in this context to nirvikalpa samadhi of Hinduism, nirodh of Hinayana Buddhism, and to the eighth of the ten ox-herding pictures of Zen Buddhism.

On Wilber’s last level, that of the Absolute, Consciousness awakens as its Original Condition and Suchness (tathagata), which is, at the same time, all that is, gross, subtle, or causal. The distinction between the witness and the witnessed disappears and the entire World Process then arises, moment to moment as one’s own Being, outside of which and prior to which nothing exists.

In a hierarchical classification based on my own data, I would include in the low subtle or astral-psychic level experiences that involve elements of the material world, but which provide information in a way that is radically different from our everyday perception. Here belong, above all, experiences that are traditionally studied by parapsychologists (and some of them also by thanatologists and therapists), such as out-of-body experiences, astral travel, ESP phenomena, precognition, and clairvoyance. I would also add to this list experiences of phenomena that are closely connected to material reality, but reveal aspects or dimensions that are not accessible to ordinary consciousness – the subtle or energy body, its conduits (nadis or meridians), fields (auras), and centers (chakras). The concept of crosspoints, bridges between the visible and invisible reality, found in Tantric literature seems to be particularly relevant in this context (Mookerjee and Khanna 1977).

I would include on the low subtle level also some important transpersonal experiences included in my cartography but not mentioned by Wilber. Here belong experiential identification with various aspects of space-time – other people, animals, plants, and inorganic materials and processes, as well as ancestral, racial, collective, phylogenetic, and karmic experiences. I have shown in my previous publications that all these experiences mediated by extrasensory channels provide access to accurate new information about the phenomena involved (Grof 1975, 1985, 1987, 2000).

I would also add here from my own classification a category of experiences that I call psychoid, using the term coined by Hans Driesch and adopted by C.G. Jung. This group includes situations in which intrapsychic experiences are associated with corresponding changes in the external world (or better in consensus reality). Psychoid experiences cover a wide range from Jung’s synchronicities (Jung 1960) and ceremonial magic to psychokinesis and other mind-over-matter phenomena, or siddhis (Grof 1988) that Patanjali assigns to the subtle level of consciousness.

The categories of my map of transpersonal experiences that could be assigned to the high subtle level include visions of divine light and epiphany, encounters with various blissful and wrathful archetypal figures, communication with spirit guides and superhuman entities, contact with shamanic power animals, direct apprehension of universal symbols, and episodes of religious and creative inspiration (the ‘Promethean epiphany’). The visions of archetypal beings or experiential identification with them can portray them in their universal form (e.g. the Great Mother Goddess) or in the form of their specific cultural manifestations (e.g. Virgin Mary, Isis, Cybele, Parvati, etc.).

Over the years, I have had the privilege to be in psychedelic and Holotropic Breathwork sessions of people who had experiences of the lower and higher causal realms and possibly even those of the Absolute. I have also had personal experiences that I believe qualify for these categories. In my classification these episodes are described under such titles as experiences of the Demiurg, Cosmic Consciousness, Absolute Consciousness, or Supracosmic and Metacosmic Void.

The existence and nature of transpersonal experiences violates some of the most basic assumptions of materialistic science. They imply such seemingly absurd notions as relativity and arbitrary nature of all physical boundaries, nonlocal connections in the universe, communication through unknown means and channels, memory without a material substrate, the nonlinearity of time, or consciousness associated with all living organisms, and even inorganic matter. Many transpersonal experiences involve events from both the microcosm and the macrocosm, realms that cannot normally be reached by unaided human senses, or from historical periods that precede the origin of the solar system, formation of planet earth, appearance of living organisms, development of the nervous system, and emergence of homo sapiens.

Mainstream academicians and physicians adhering to the monistic materialistic worldview have no other choice than denying the existence and authenticity of transpersonal experiences or relegating them to the category of “anomalous phenomena.” However, there have been serious attempts to provide for them scientific conceptual framework and integrate them into a revolutionary new worldview. In an intellectualtour de force and a series of books, the world’s foremost system theorist, interdisciplinary scientist, and philosopher, Ervin Laszlo, has explored a wide range of disciplines, including astrophysics, quantum-relativistic physics, biology, and transpersonal psychology (Laszlo 1993, 1999, 2003, 2004a, 2004b). He pointed out a wide range of phenomena, paradoxical observations, and paradigmatic challenges, for which these disciplines have no explanations. Drawing on revolutionary advances of twentieth century’ science, he offered a brilliant solution to the anomalies and paradoxes, which currently plague many of its fields. Laszlo achieved that by formulating his connectivity hypothesis, the main cornerstone of which is the existence of what he called the psi-fieldand, more recently, the Akashic Field. (Laszlo 2003, 2004b).

Laszlo describes it as a subquantum field, which is the source of all creation and holds a holographic record of all the events that have happened in the phenomenal world. He equates this field with the conceptof quantum vacuum (or better quantum plenum) that has emerged from modern physics (Laszlo 2003, 2004). Laszlo’s connectivity hypothesis provides a scientific explanation for otherwise mysterious transpersonal experiences that in the context of mainstream materialistic science appear to be impossible or are referred to as “anomalous” phenomena. Here belong, for example, experiential identification with other people and with representatives of other species, group consciousness, possibility of experiencing episodes from other historical periods and countries including past life experiences, telepathy, remote viewing and other psychic abilities, out-of-body experiences, astral projection, the experience of the Supracosmic and Metacosmic Void, and others.

An alternative conceptual framework that can account for for many of the baffling properties of transpersonal experiences is process philosophy of the English mathematician, logician, and philosopher Alfred North Whitehead (Whitehead 1978). Whitehead’s metaphysical system is of particular interest, because it does not grant fundamental metaphysical status to matter, but places central focus on experience or mind. According to process philosophy, the basic element of which the universe is made is not enduring substance, but moment of experience, called in his terminology actual occasion. The universe is composed of countless discontinuous bursts of experiential activity on all the levels of reality, from subatomic particles to human souls. The relevance of Whitehead’s philosophy for transpersonal psychology and consciousness research has been explored in the writings of John Buchanan, David Ray Griffin, John Quiring, Leonard Gibson, and Grant Maxwell (Buchanan 1994, 2001, 2002 and 2005, Griffin 1989 and 1996, Quiring 1996, Gibson 19, and Maxwell 2011).

Having spent more than half a century studying transpersonal experiences, I have no doubt that they are ontologically real and are not products of metaphysical speculation, human imagination, or pathological processes in the brain. By the term ontologically real, I refer to a category of experiences which not only possess the subjective sense of reality, but whose contents also seem to reveal something of the nature or essential qualities of being or existence. It would be erroneous to dismiss them as products of fantasy, primitive superstition, or manifestations of mental disease, as has so frequently been done.

Anybody attempting to do that would have to offer a plausible explanation why these experiences have in the past been described so consistently by people of various races, cultures, and historical periods. He or she would also have to account for the fact that these experiences continue to emerge in modern populations under such diverse circumstances as sessions with various psychedelic substances, during experiential psychotherapy, in meditation of people involved in systematic spiritual practice, in near-death experiences, and in the course of spontaneous episodes of psychospiritual crisis. Detailed discussion of the transpersonal domain, including descriptions and examples of various types of transpersonal experiences can be found in my various publications (Grof 1975, 1987, and 2000).

In view of this vastly expanded model of the psyche, we could now paraphrase Freud’s simile of the psyche as an iceberg. We could say that everything Freudian analysis has discovered about the psyche represents just the top of the iceberg showing above the water. Research of holotropic states has made it possible to explore the colossal rest of the iceberg hidden under water, which has escaped the attention of Freud and his followers, with the exception of the remarkable renegades Otto Rank and C.G. Jung. Mythologist Joseph Campbell, known for his incisive Irish humor, used a different metaphor: “Freud was fishing while sitting on a whale.”

3. The Nature, Function, and Architecture of Emotional and Psychosomatic Disorders

To explain various emotional and psychosomatic disorders that do not have an organic basis (“psychogenic psychopathology”), traditional psychiatrists use a superficial model of the psyche limited to postnatal biography and the individual unconscious. They believe that these conditions originate in infancy and childhood as a result of various emotional traumas and interpersonal dynamics in the family of origin. There seems to be general agreement in schools of dynamic psychotherapy that the depth and seriousness of these disorders depend on the timing of the original traumatization.

Thus, according to classical psychoanalysis, the origin of alcoholism, narcotic drug addiction, and manic-depressive disorders can be found in the oral period of libidinal development, obsessive-compulsive neurosis has its roots in the anal stage, phobias and conversion hysteria result from traumas incurred in the “phallic phase” and at the time of the Oedipus and Electra complex, and so on (Fenichel 1945). Later developments in psychoanalysis linked some very deep disorders – autistic and symbiotic infantile psychoses, narcissistic personality, and borderline personality disorders – to disturbances in the early development of object relations (Black and Black 1974 and 1979). As I mentioned earlier, this does not apply to Rankian and Jungian therapists who are aware of the fact that the roots of emotional disorders reach deeper into the psyche.

The above conclusions have been drawn from observations of therapists using primarily verbal means. The understanding of psychogenic disorders changes radically if we employ methods that involve holotropic states of consciousness. These approaches engage levels of the unconscious which are generally out of reach of verbal therapy. Initial stages of this work typically uncover relevant traumatic material from early infancy and childhood that is meaningfully related to emotional and psychosomatic problems and appears to be their source. However, when the process of uncovering continues, deeper layers of the unconscious unfold and we find additional roots of the same problems on the perinatal level and on the transpersonal level of the psyche.

Various avenues of work with holotropic states, such as psychedelic therapy, Holotropic Breathwork, rebirthing, and primal therapy, or psychotherapy with people experiencing spontaneous psychospiritual crises, have shown that emotional and psychosomatic problems cannot be adequately explained as resulting exclusively from postnatal psychotraumatic events. In my experience, the unconscious material associated with them typically forms multilevel dynamic constellations for which I have coined the term systems of condensed experience or COEX systems (Grof 1975, 2000).

A typical COEX system consists of many layers of unconscious material that share similar emotions or physical sensations; the contributions to a COEX system come from different levels of the psyche. More superficial and easier available layers contain memories of emotional or physical traumas from infancy, childhood, and later life. On a deeper level, each COEX system is typically connected to a certain aspect of the memory of birth, a specific BPM; the choice of this matrix depends on the nature of the emotional and physical feelings involved. For example, if the theme of the COEX system is victimization, this would be BPM II, if it is fight against a powerful adversary or sexual abuse, the connection would be with BPM III, for a positive COEX comprising memories of deeply satisfying and fulfilling situations it would be BPM IV, and so on.

The deepest roots of COEX systems underlying emotional and psychosomatic disorders reach into the transpersonal domain of the psyche. They have the form of ancestral, racial, collective, and phylogenetic memories, experiences that seem to be coming from other lifetimes (“past life memories”), and various archetypal motifs. Thus therapeutic work on anger and disposition to violence can, at a certain point, take the form of experiential identification with a tiger or a black panther, the deepest root of serious antisocial behavior can be a demonic archetype, the final resolution of a phobia can come in the form of reliving and integration of a past life experience, and so on.

The overall architecture of the COEX systems can best be shown using a clinical example. A person suffering from psychogenic asthma might discover in serial breathwork sessions a powerful COEX system underlying this disorder. The biographical part of this constellation might consist of a memory of near drowning at the age of seven, memories of being repeatedly strangled by an older brother between the ages of three and four, and a memory of severe choking during whooping cough or diphtheria at the age of two. The perinatal contribution to this COEX would be, for example, suffocation experienced during birth because of strangulation by the umbilical cord twisted around the neck. A typical transpersonal root of this breathing disorder would be an experience of being hanged or strangled in what seems to be a previous lifetime. A detailed discussion of COEX systems, including additional examples appears in several earlier publications (Grof 1975, 1987, and 2000).

4. Effective Therapeutic Mechanisms

Traditional psychotherapy knows only therapeutic mechanisms operating on the level of the biographical material, such as weakening of the psychological defense mechanisms, remembering of forgotten or repressed traumatic events, reconstructing the past from dreams or neurotic symptoms, attaining intellectual and emotional insights, analysis of transference, and corrective experience in interpersonal relations. Psychotherapy using holotropic states of consciousness offers many additional highly effective mechanisms of healing and personality transformation, which become available when experiential regression reaches the perinatal and transpersonal levels. Among these are actual reliving of traumatic memories from infancy, childhood, biological birth, and prenatal life, past life memories, emergence of archetypal material, experiences of cosmic unity, and others.

I will illustrate this therapeutic dynamics by the story of a participant in one of our workshops at the Esalen Institute in Big Sur, California, whom I will call Norbert.

t the beginning of the workshop, Norbert complained about severe chronic pain in his left shoulder and pectoral muscle that had caused him great suffering and made his life miserable. Repeated medical examinations, including X-rays, had not detected any organic basis for his problem and all therapeutic attempts had remained unsuccessful. Serial Procaine injections had brought only brief transient relief for the duration of the pharmacological effect of the drug.

Norbert’s session was long and very dramatic. In the sharing group, he described that there were three different layers in his experience, all of them related to the pain in his shoulder and associated with choking. On the most superficial level, he relived a frightening situation from his childhood in which he almost lost his life. When he was about seven years old, he and his friends were digging a tunnel on a sandy ocean beach. When the tunnel was finished, Norbert crawled inside to explore it. As the other children jumped around, the tunnel collapsed and buried him alive. He almost choked to death before he was rescued by the adults, who arrived responding to the children’s alarming screams.

When the breathwork experience deepened, Norbert relived a violent and terrifying episode that took him back to the memory of his biological birth. His delivery was very difficult, since his shoulder was stuck for an extended period of time behind the pubic bone of his mother. This episode shared with the left shoulder.

In the last part of the session, the experience changed dramatically. Norbert started seeing military uniforms and horses and recognized that he was involved in a fierce battle. He was even able to identify it as one of the battles in Cromwell’s England. At one point, he felt a sharp pain in his left shoulder and realized that it had been pierced by a lance. He fell off the horse and experienced himself as being trampled by the horses running over his body and crushing his chest. His broken rib cage caused him agonizing pain, and he was choking on blood, which was filling his lungs.

After a period of extreme suffering, Norbert’s consciousness separated from his dying body, soared high above the battlefield, and observed the scene from a bird’s eye view. Following the death of the severely wounded soldier, whom he recognized as himself in a previous incarnation, Norbert’s consciousness returned to the present time and reconnected with his body, which was now pain-free for the first time after many years of agony. The relief from pain brought about by these experiences turned out to be permanent.

5. Strategy of Psychotherapy and Self-Exploration

The most astonishing aspect of modern psychotherapy is the number of competing schools and the lack of agreement among them. They have vast differences of opinion concerning the most fundamental issues, such as: what are the dimensions of the human psyche and what are its most important motivating forces; why do symptoms develop and what they mean; which issues that the client brings into therapy are central and which are less relevant; and, finally, what technique and strategy should be used to correct or improve the emotional, psychosomatic, and interpersonal functioning of the clients.

The goal of traditional dynamic psychotherapies is to reach intellectual understanding of the human psyche, in general, and that of a specific client, in particular, and then use this knowledge in developing an effective therapeutic technique and strategy. An important tool in many modern psychotherapies is “interpretation;” it is a way in which the therapist reveals to the client the “true” or “real” meaning of his or her thoughts, emotions, and behavior. This method is widely used in analyzing dreams, neurotic symptoms, behavior, and even seemingly trivial everyday actions, such as slips of the tongue or other small errors, Freud’s “Fehlleistungen” (Freud 1960a). Another area in which interpretations are commonly applied is interpersonal dynamics, including transference of various unconscious feelings and attitudes on the therapist.

Therapists spend much effort trying to determine what is the most fitting interpretation in a given situation and what is the appropriate timing of this interpretation. Even an interpretation that is “correct” in terms of its content, can allegedly be useless or harmful for the patient if it is offered prematurely, before the client is ready for it. A serious flaw of this approach to psychotherapy is that individual therapists, especially those who belong to diverse schools, would attribute very different value to the same psychological content or behavior and offer for it diverse and even contradictory interpretations. This can be illustrated by a humorous example from my own psychoanalytic training.

As a beginning psychiatrist, I was in training analysis that involved three sessions a week for a period of over seven years; my analyst was the Nestor of Czechoslovakian psychoananalysis and president of the Czechoslovakian Psychoanalytic Association, Dr. Theodor Dosužkov. At the time of my analysis, Dr. Dosužkov was in his late sixties and it was known among his analysands – all young psychiatrists – that he had a tendency to occasionally doze-off during analytic hours. Dr.Dosužkov’s habit was a favorite target of jokes of his students.

Besides individual sessions of training psychoanalysis, Dr. Dosužkov also conducted seminars, where his students shared reviews of books and articles, discussed case histories, and could ask questions about theory and practice of psychoanalysis. In one of these seminars, a participant asked a “purely theoretical” question: “What happens if during analysis the psychoanalyst falls asleep? If the client continues free-associating, does therapy continue? Is the process interrupted? Should the client get refunded for that time, since money is such an important vehicle in Freudian analysis?”

Dr. Dosužkov could not deny that such a situation could occur in psychoanalytic sessions. He knew that the analysands knew about his foible and he had to come up with an answer. “This can happen,” he said. “Sometimes, you are tired and sleepy – you did not sleep well the night before, you are recovering from a flu, or are physically exhausted. But, if you have been in this business a long time, you develop a kind of “sixth sense;” you fall asleep only when the stuff that is coming up is irrelevant. When the client says something really important, you wake up and you are right there!”

Dr. Dosužkov was also a great admirer of I.P. Pavlov, a Russian Nobel Prize-winning physiologist who derived his knowledge of the brain from his experiments with dogs. Pavlov wrote much about the inhibition of the cerebral cortex that occurs during sleep or hypnosis; he described that sometimes there could be a “waking point” in the inhibited brain cortex. His favorite example was a mother who can sleep through heavy noises, but awakens immediately when her own child is moaning. “It is just like the situation of the mother Pavlov wrote about,” explained Dr. Dosužkov, “with enough experience, you will be able to maintain connection with your client even when you fall asleep.”

There was clearly a problem with Dr. Dosužkov’s explanation. What a therapist considers to be relevant in the client’s narrative reflects his or her training and personal bias. Had I had an Adlerian, Rankian, or Jungian therapist instead of a Freudian one, they would have awakened at different times of the session, each at the moment when my narrative would bring something that, according to their judgment, was “relevant.”

Because of the great conceptual differences between the schools of depth psychology, the question naturally arises which of them has a more correct understanding of the human psyche in health and disease. If it were true that correct and properly timed interpretations are a significant factor in psychotherapy, there would have to be great differences in the therapeutic success achieved by various schools. Their therapeutic results could be mapped on a Gaussian curve; therapists of the school with the most accurate understanding of the psyche and, therefore, most fitting interpretations would have the best results and those belonging to orientations with less accurate conceptual frameworks would be distributed on the descending parts of the curve.

To my knowledge, there are not any scientific studies showing clear superiority of some schools of psychotherapy over others as measured by outcomes (Frank and Frank 1991). If anything, the differences are found within the schools rather than between them. In each school there are better therapists and worse therapists. And, very likely, the therapeutic results have very little to do with what the therapists think they are doing – the accuracy and good timing of interpretations, correct analysis of transference, and other specific interventions. Successful therapy probably depends on factors that do not have much to do with intellectual brilliance and are difficult to describe in scientific language, such as the “quality of the human encounter” between therapists and clients, the feeling of the clients that they are unconditionally accepted by another human being, frequently for the first time in their life, or the hope that the client feels during the therapeutic process.

The lack of generally accepted theory of psychotherapy and of basic agreement concerning therapeutic practice is very disconcerting. Under these circumstances, a client who has an emotional or psychosomatic disorder can choose a school by flipping a coin. With each school comes a different explanation of the problem he or she brought into therapy and a different technique is offered as the method of choice to overcome it. Similarly, when a beginning therapist seeking training chooses a particular therapeutic school, it says more about the personality of the applicant than the value of the school.

The problem with many of the psychotherapeutic schools is that they correctly describe the dynamics on a certain level of the psyche but lack the understanding of the phenomena from other levels and try to interpret them in terms of their own conceptual framework. For example, Freud’s system was limited to postnatal biography and the individual unconscious; he was not aware of the paramount importance of birth, except for a short period when he thought birth anxiety might be the template for all future anxieties (Freud 1959). He also did not accept the existence of the collective unconscious and tried to interpret archetypal/mythological and parapsychological phenomena in terms of his narrow biographical model. Otto Rank, who discovered the psychological importance of the trauma of birth, offered explanations of mythological and spiritual/religious motifs that described them as derivatives of perinatal dynamics. C.G. Jung, who discovered and described the vast domains of the historical and archetypal collective unconscious, was unable to see the psychological importance of the birth trauma. In an interview with Dr. Richard I. Evans, he laughingly dismissed Otto Rank’s theory: “Oh, birth is not a trauma, it is a fact; everybody is born” (Jung 1957a). An effective psychotherapeutic system has to recognize and respect all the levels of the psyche. The unconscious content that is explored and processed, as it unfolds from session to session, is determined by the client’s own process. The therapist needs to have a broad enough conceptual framework to be able to accompany the clients to any level of their unconscious psyche – biographical, perinatal, and/or transpersonal and support their respective experiences (Vaughan 1993).

It is interesting to see how therapy using holotropic states of consciousness can help us to avoid the dilemmas inherent in the situation described above. The alternative that this work brings actually confirms some ideas about the therapeutic process first outlined by C.G. Jung. According to Jung, it is impossible to achieve intellectual understanding of the psyche and derive from it a technique that we can use in psychotherapy. As he saw it in his later years, the psyche is not a product of the brain and is not contained in the skull; it is the creative and generative principle of the cosmos (anima mundi). It permeates all of existence and the individual psyche of each of us is teased out of this unfathomable cosmic matrix. The boundaries between the anima mundi and the individual psyche are not absolute; they are permeable and can be transcended in holotropic states. The intellect is a partial function of the psyche that can help us orient ourselves in everyday situations. However, it is not in a position to fathom the deepest mysteris of existence and comprehend and manipulate the psyche.

There is a wonderful passage in Victor Hugo’s Les Misérables: “There is one spectacle grander than the sea, that is the sky; there is one spectacle grander than the heavens; that is the interior of the soul.” Jung was aware of the fact that the psyche is a profound mystery and approached it with great respect. It was clear to him that the psyche is infinitely creative and cannot be described by a set of formulas that can then be used to correct the psychological processes of the clients. He suggested an alternative strategy for therapy that was significantly different from using intellectual constructs and external interventions.

What a psychotherapist can do, according to Jung, is to create a supportive environment, in which psychospiritual transformation can occur; this container can be compared to the hermetic vessel that makes alchemical processes possible. The next step then is to offer a method that mediates contact between the conscious ego and a higher aspect of the client, the Self. One of Jung’s tools for this purpose wasactive imagination, involving continuation of a dream on the analyst’s couch and its analysis in statu nascendi (von Franz 1997), rather than retrospective analysis of the dream from memory. This was different from Freud’s interetation of dreams from memories, sometimes month or even years old. The communication between the ego and the Self occurs primarily by means of symbolic language. In Jung’s. own words, “active imagination is a process of consciously dialoguing with our unconscious for the production of those contents of the unconscious which lie, as it were, immediately below the threshold of consciousness and, when intensified, are the most likely to erupt spontaneously into the conscious mind.” In this kind of work, healing is not the result of brilliant insights and interpretations of the therapist; the therapeutic process is guided from within the client’s psyche.

In Jung’s understanding, the Self is the central archetype in the collective unconscious and its function is to lead the individual toward order, organization, and wholenes. Jung referred to this movement toward highest unity as the individuation process. The use of holotropic states for therapy and self-exploration essentially confirms Jung’s perspective and follows the same strategy. The facilitators create a protective and supportive environment and help the clients enter a holotropic state. Once that occurs, the healing process is guided from within by the clients’ own inner healing intelligence and the task of the facilitators is to support what is happening. This process automatically activates unconscious material, which has strong emotional charge and and is close enough to consciousness to be available for processing on the day of the session.

This saves the facilitators the hopeless task to sort out what is “relevant” and what is not that plagues verbal therapies. They simply support whatever is spontaneously emerging and manifesting from moment to moment, trusting that the process is guided by intelligence that surpasses the intellectual understanding which can be obtained by professional training in any of the schools of psychotherapy. Clients and participants in workshops and training might be using terms like COEX systems, BPMs, archetypes, and so on, but this will reflect their direct experiential engagement with whatever has spontaneously arisen and not be offered as interpretation by facilitators.

6. The Role of Spirituality in Human Life

The leading philosophy of Western science has been monistic materialism. Various scientific disciplines have described the history of the universe as history of developing matter and they accept as real only what can be measured and weighed. Life, consciousness, and intelligence are then seen as more or less accidental side-products of material processes. Physicists, biologists, and chemists recognize the existence of dimensions of reality that are not accessible to our senses, but only those that are physical in nature and can be revealed and explored with the use of various extensions of our senses, such as microscopes, telescopes, and specially designed recording devices, or laboratory experiments.

In a universe understood this way, there is no place for spirituality of any kind. The existence of God, the idea that there are invisible dimensions of reality inhabited by nonmaterial beings, the possibility of survival of consciousness after death, and the concept of reincarnation and karma have been relegated to books of fairy tales and handbooks of psychiatry. From a psychiatric perspective to take such things seriously means to be ignorant, unfamiliar with the discoveries of materialistic science, to besuperstitious and subject to primitive magical thinking. If the belief in God or Goddess occurs in intelligent persons, it is seen as an indication that they have not come to terms with infantile images of their parents as omnipotent beings they had created in their infancy and childhood and project them into the Beyond. And direct experiences of spiritual realities, including encounters with mythological beings and visits to archetypal realms are considered manifestations of serious mental diseases – psychoses.

The study of holotropic states has thrown new light on the problem of spirituality and religion. The key to this new understanding is the discovery that in these states it is possible to encounter a rich array of experiences which are very similar to those that inspired the great religions of the world – visions of God and various divine and demonic beings, encounters with discarnate entities, episodes of psychospiritual death and rebirth, visits to Heaven and Hell, past life experiences, and many others. Modern research has shown beyond any doubt that these experiences are not products of fantasy or pathological processes afflicting the brain, but manifestations of archetypal material from the collective unconscious, and thus are germane and essential constituents of the human psyche. Although these mythic elements are accessed intrapsychically, in a process of experiential self-exploration and introspection, they are ontologically real, have objective existence. To distinguish transpersonal experiences from imaginary products of individual human fantasy or psychopathology, Jungians refer to this domain as imaginal.

French scholar, philosopher, and mystic, Henri Corbin, who first used the term mundus imaginalis, got the inspiration for this concept from his study of Islamic mystical literature (Corbin 2000). Islamic theosophers call the imaginal world, where everything existing in the sensory world has its analogue, ‘alam a mithal,’ or the “eighth climate,” to distinguish it from the “seven climates,” or regions of traditional Islamic geography. The imaginal world possesses extension and dimensions, forms and colors, but these are not perceptible to our senses as they would be when they are properties of physical objects. However, this realm is in every respect as fully ontologically real as the material world perceived by our sensory organs and experiences of it can be verified by consensual validation by other people.

In view of these observations, the fierce battle that religion and science have fought over the last several centuries nowappears ludicrous and completely unnecessary. Genuine science and authentic religion do not compete for the same territory; they represent two approaches to existence, which are complementary, not competitive. Science studies phenomena in the material world, the realm of the measurable and weighable, while genuine spirituality and true religion draw their inspiration from experiential knowledge of the imaginal world as it manifests in holotropic states of consciousness. The conflict that seems to exist between religion and science reflects fundamental misunderstanding of both. As Ken Wilber has pointed out, there cannot possibly be a conflict between science and religion, if both of these fields are properly understood and practiced. If there seems to be a conflict, we are likely dealing with “bogus science” and “bogus religion” (Wilber 1982). The apparent incompatibility is due to the fact that either side seriously misunderstands the other’s position and very likely represents also a false version of its own discipline.

The only scientific endeavor that can make any relevant and valid judgments about spiritual matters is consciousness research studying holotropic states, since it requires intimate knowledge of the imaginal realm. In his ground-breaking essay, Heaven and Hell, Aldous Huxley suggested that such concepts as Hell and Heaven represent intrapsychic realities experienced in a very convincing way during non-ordinary states of consciousness induced by psychedelic substances, such as LSD and mescaline, or various powerful non-drug techniques (Huxley 1959). The seeming conflict between science and religion is based on the erroneous belief that these abodes of the Beyond are located in the physical universe – Heaven in the interstellar space, Paradise somewhere in a hidden area on the surface of our planet, and Hell in the interior of the earth.

Astronomers have created and used extremely sophisticated devices, such as the Hubble Space Telescope, to explore and map carefully the entire vault of heaven. Results of these efforts, which have of course failed to find God and heaven replete with harp-playing angels and saints, have been taken as proof that such spiritual realities do not exist. Similarly, in cataloguing and mapping every acre of the planetary surface, explorers and geographers have found many areas of extraordinary natural beauty, but none of them matched the descriptions of Paradises found in spiritual scriptures of various religions. Geologists have discovered that the core of our planet consists of layers of solid and molten nickel and iron, and that its temperature exceeds that of the sun’s surface. This certainly is not a very plausible location for the caves of Satan.

Modern studies of holotropic states have brought strong supportive evidence for Huxley’s insights. They have shown that Heaven, Paradise, and Hell are ontologically real; they represent distinct and important states of consciousness that all human beings can under certain circumstances experience during their lifetime. Celestial, paradisean, and infernal visions are a standard part of the experiential spectrum of psychedelic inner journeys, near-death states, mystical experiences, as well as shamanic initiatory crises and other types of “spiritual emergencies.” Psychiatrists often hear from their patients about experiences of God, Heaven, Hell, archetypal divine and demonic beings, and about psychospiritual death and rebirth. However, because of their inadequate superficial model of the psyche, they misinterpret them as manifestations of mental disease caused by a pathological process of unknown etiology. They do not realize that matrices for these experiences exist in deep recesses of the collective unconscious psyche of every human being.

An astonishing aspect of transpersonal experiences occurring in holotropic states of various kinds is that their content can be drawn from the mythologies of any culture of the world, including those of which the individual has no intellectual knowledge. C.G. Jung demonstrated this extraordinary fact for mythological experiences occurring in the dreams and psychotic experiences of his patients. On the basis of these observations, he realized that the human psyche has access not only to the Freudian individual unconscious, but also to the collective unconscious, which is a repository of the entire cultural heritage of humanity (Jung 1956, 1959). Knowledge of comparative mythology is thus more than a matter of personal interest or an academic exercise. It is a very important and useful guide for individuals involved in experiential therapy and self-exploration and an indispensable tool for those who support and accompany them on their journeys (Grof 2006).

The experiences originating on deeper levels of the psyche, in the collective unconscious, have a certain quality that Jung referred to asnuminosity. The word numinous – first used by Rudolf Otto – is relatively new and neutral and thus preferable to other similar expressions, such as religious, mystical, magical, holy, or sacred, which have often been used in problematic contexts and are easily misleading. The term numinosity applied to transpersonal experiences describes direct perception of their extraordinary nature which Otto describes with the terms mysterium tremendum et fascinans and wholly other – something that cannot be usually experienced in our everyday states of consciousness. They convey a very convincing sense that they belong to a higher order of reality, a realm which is sacred.

In view of the ontological reality of the imaginal realm, spirituality is a very important and natural dimension of the human psyche and spiritual quest is a legitimate and fully justified human endeavor. However, it is necessary to emphasize that this applies to genuine spirituality based on personal experience and does not provide support for ideologies and dogmas of organized religions. To prevent misunderstanding and confusion that in the past compromised many similar discussions, it is critical to make a clear distinction between spirituality and religion.

Spirituality involves a special kind of relationship between the individual and the cosmos and is, in its essence, a personal and private affair. By comparison, organized religion is institutionalized group activity that takes place in a designated location, a temple or a church, and involves a system of appointed officials who might or might not have had personal experiences of spiritual realities themselves. Once a religion becomes organized, it often completely loses the connection with its spiritual source and becomes a secular institution that canexploit human spiritual needs without satisfying them.

Organized religions tend to create hierarchical systems focusing on the pursuit of power, control, politics, money, possessions, and other worldly concerns. Under these circumstances, religious hierarchy as a rule dislikes and discourages direct spiritual experiences in its members, because they foster independence and cannot be effectively controlled. When this is the case, genuine spiritual life continues only in the mystical branches, monastic orders, and ecstatic sects of the religions involved. People who have experiences of the immanent or transcendent divine open up to spirituality found in the mystical branches of the great religions of the world or in their monastic orders, not necessarily in their mainstream organizations. A deep mystical experience tends to dissolve the boundaries between religions and reveals deep connections between them, while the dogmatism of organized religions tends to emphasize differences between various creeds and engender antagonism and hostility.

There is no doubt that the dogmas of organized religions when interprted literally are generally in fundamental conflict with science, whether this science uses the mechanistic-materialistic model or is anchored in the emerging paradigm. However, the situation is very different in regard to authentic mysticism based on genuine spiritual experiences. The great mystical traditions have amassed extensive knowledge about human consciousness and about the spiritual realms in a way that is similar to the method that scientists use in acquiring knowledge about the material world. They include methodologies for inducing transpersonal experiences, systematic collection of data, and intersubjective validation.

Spiritual experiences, like any other aspect of reality, can be subjected to careful open-minded research and studied scientifically. There is nothing unscientific about unbiased and rigorous study of transpersonal phenomena and of the challenges they present for materialistic understanding of the world. Only such an approach can answer the critical question about the ontological status of mystical experiences: Can they reveal deep truth about some basic aspects of existence, as maintained by various systems of perennial philosophy and transpersonal psychology, or are they products of superstition, fantasy, or mental disease, as Western materialistic science sees them?

Official psychiatry makes no distinction between a mystical experience and a psychotic experience and sees both as manifestations of mental disease. In its rejection of religion, it does not differentiate between primitive folk beliefs or the fundamentalist literal interpretations of religious scriptures and sophisticated mystical traditions or the great Eastern spiritual philosophies based on centuries of systematic introspective exploration of the psyche. Modern consciousness research has brought convincing evidence for the objective existence of the imaginal realm and has thus validated the main metaphysical assumptions of the mystical world view, of the Eastern spiritual philosophies, and even certain beliefs of indigenous cultures.

7. The Importance of Archetypal Psychology and Transit Astrology

The greatest surprise I have experienced during the fifty some years I have been involved in consciousness research was the discovery of the extraordinary predictive power of astrology. Because of my strict scientific training, my initial skepticism concerning astrology was very strong and persistent. The idea that planets and stars could have anything to do with states of consciousness, let alone events in the world, seemed too absurd and preposterous to be taken seriously. It took years and thousands of convincing observations to accept this possibility; it required nothing less than a radical revision of my basic metaphysical assumptions about the nature of reality. Since I am aware how controversial and charged this issue is, I do not think I would have included the discussion of astrology in this presentation, if it were not for the fact that Richard Tarnas has published three remarkable books on his meticulous ground-breaking research: The Passion of the Western Mind, Prometheus the Awakener, and Cosmos and Psyche(Tarnas 1993, 1995, and 2006).

Over the last thirty years, Rick and I have jointly explored astrological correlations with holotropic states. My main task has been to collect interesting clinical observations from psychedelic sessions, Holotropic Breathwork workshops and training, mystical experiences, spiritual emergencies, and psychotic breaks. Rick’s main focus has been on astrological aspects of holotropic states of consciousness. This cooperation has brought convincing evidence that there exist systematic correlations between the nature, timing, and content of holotropic states of consciousness and planetary transits of the individuals involved.

The first indication that there might be some extraordinary connection between astrology and my research of holotropic states was the realization that my description of the phenomenology of the four basic perinatal matrices (BPMs), experiential patterns associated with the stages of biological birth, showed astonishing similarity to the four archetypes that astrologers link to the four outer planets of the solar system – BPM I to Neptune, BPM II to Saturn, BPM III to Pluto, and BPM IV to Uranus. It is important to emphasize that my description of the phenomenology of the BPMs was based on clinical observations made quite independently many years before I knew anything about astrology.

Even more astonishing was the discovery that in holotropic states the experiential confrontation with these matrices regularly occurs at the time when the individuals involved have important transits of the corresponding planets. Over the years, we have been able to confirm this fact by thousands of specific observations and discover further astrological correlations for many other aspects of holotropic states. Because of these surprisingly precise correlations, astrology, particularly transit astrology, turned out to be an invaluable instrument for consciousness research.

This is a vast and extremely important topic and I cannot do it justice in the context of this article. Interested readers will find some more information in my two articles on holotropic states and archetypal astrology (Grof 2010 and Grof in print), but adequate discussion of these remarkable findings will require a separate volume and be written by a professional astrologer. But I have seen enough evidence in the last thirty years to say at this point a few words concerning my present understanding of the relationship between the timing and nature of holotropic states, spontaneous or induced, and transit astrology. We have repeatedly seen that the consciousness of the individuals who enter a holotropic state, seem to get under the influence of the archetypal fields associated with the planets transiting at the time their natal chart.

Within this context, they tune experientially into a COEX system with the corresponding archetypal quality. Depending on the power of the archetypal energies involved, the depth and intensity of the experience, and the number of previous exposures to holotropic states, the emerging material will consist of selections of biographical, perinatal, and/or transpersonal memories and motifs combining these archetypal characteristics in various, often very creative ways. Although I am well aware that this cursory comment will not have much impact on readers who have no previous knowledge of astrology, it might serve as inspiration and instigation for experienced astrologers to verify or disprove these observations by their own research.

We are currently experiencing an extraordinary renaissance of psychedelic research, with several major American university conducting new studies, Holotropic Breathwork workshops are available in many countries of the world, and spontaneous episodes of holotropic states abound. For those readers interested in verifying or disproving the conclusions made in this paper should thus have ample research material to work with. However, it is important to emphasize that the astrological predictions, although extraordinarily accurate, are archetypically predictive rather than concretely predictive. One of the striking properties of the archetypes revealed by Richard Tarnas’ pioneering research is their complex multivalence. Each archetype and archetypal combination has a rich spectrum of meanings, while at the same time remaining true to its own specific nature (for example, although Saturn and Neptune each have a wide array of meanings, an experienced astrologer would never confuse any essential elements associated with one of these archetypes with those of the other).

In my present understanding, archetypal astrology is the long-sought Rosetta stone of consciousness research, providing a key for understanding the nature and content of present, past, and future holotropic states, both spontaneous and induced. I now strongly believe that responsible work with holotropic states combined with archetypal astrology as a guide represents the most promising trend in psychiatry, psychology, and psychotherapy.

Bibliography

Bateson, G. et al. 1956. Towards a Theory of Schizophrenia. Behavioral Science, vol 1, 251–264.

Bateson, G. 1972. “Form, Substance and Difference.” In: Steps to An Ecology of Mind. San Francisco: Chandler Publications.

Black, G. and Black, R. 1974. Ego Psychology I: Theory and Practice. New York: Columbia University Press.

Black, G. and Black, R. 1979. Ego Psychology II: Psychoanalytic Developmental Psychology. New York: Columbia University Press.

Buchanan, J.H. 1994. Universal Feeling: Whitehead and Psychology. A Ph.D. dissertation submitted to the Faculty of the Graduate School of Emory University Graduate Institute of the Liberal Arts.

Buchanan, J. H. 2001. Cosmic Consciousness in A Process Cosmology. Paper for the 86th Annual Congress of the International New Thought Alliance, Harrah Hotel, Las Vegas, NV.

Buchanan, J. H. 2002. Grof and Whitehead: Visions of a Postmodern Cosmology. Helios Foundation, Atlanta, GA.

Buchanan, J. H. 2005. Openness: Spirituality in a Process Psychology. A paper for the Conference on Science and Spirituality, Wuhan, China, October.

Corbin, H. 2000. “Mundus Imaginalis, Or the Imaginary and the Imaginal.” In: Working With Images (B. Sells, ed.). Woodstock, Connecticut: Spring Publications 71-89.

Frank, J.D. and Frank, J. B. 1991. Persuasion and Healing: A Comparative Study of Psychotherapy. Baltimore: The Johns Hopkins University Press.

Franz, M.-L. von. 1997. Alchemical Active Imagination. New York: C.G. Jung Foundation Books.

Freud, S. 1959. Inhibitions, Symptoms, and Anxiety. The Standard edition of the Complete Psychological Works of Sigmund Freud, London: Hogart Press. vol. XX, pp. 83ff.

Griffin, D. R.1989. Archetypal Process: Self and Divine in Whitehead, Jung, and Hillman. Evanston, IL: Northwestern University Press.

Griffin, D. R. 1996. “Whitehead as a Transpersonal Philosopher.” Paper for the Transpersonal and Process Thought Conference, Esalen Institute Big Sur, CA, March 17-22.

Grof, S. 1975. Realms of the Human Unconscious: Observations from LSD Research. New York: Viking Press. Republished in 2009 as LSD: Doorway to the Numinous. Rochester, VT: Inner Traditions.

Grof, S. 1985. Beyond the Brain: Birth, Death, and Transcendence in Psychotherapy. Albany, NY: State University of New York (SUNY) Press.

Grof, S. 1987. The Adventure of Self-Discovery. Albany, NY: State University of New York (SUNY) Press.

Grof, S. and Grof, C. 1989. Spiritual Emergency: When Personal Transformation Becomes a Crisis. Los Angeles, CA: J.P. Tarcher.

Grof, C. and Grof, S. 1991. The Stormy Search for the Self: A Guide to Personal Growth Through Transformational Crises. Los Angeles, CA: J.P. Tarcher.

Grof, S. 1998. The Cosmic Game: Explorations of the Frontiers of Human Consciousness. Albany, NY: State University of New York (SUNY) Press.

Grof, S. 2000. Psychology of the Future. Albany, NY: State University of New York (SUNY) Press.

Grof, S. 2006. When the Impossible Happens: Adventures in Non-Ordinary Realities. Louisville, CO: Sounds True.

Grof, S. 2009. “Holotropic Research and Archetypal Astrology.” Archai: The Journal of Archetypal Cosmology, volume 1, Number 1 (Summer)

Grof, S. “An Archetypal Astrological Analysis of Holotropic States in Psychedelic Sessions and Spiritual Emergencies: Two Case Studies.” Archai: The Journal of Archetypal Cosmology, in print.

Hameroff, S. 1987. Ultimate Computing. North Holland: Elsevier Publishing.

Huxley, A. 1959. The Doors of Perception and Heaven and Hell. Harmondsworth, Middlesex, Great Britain: Penguin Books.

Jung, C.G. 1956. Symbols of Transformation. Collected Works, vol. 5, Bollingen Series XX, Princeton, NJ: Princeton University Press.

Jung, C.G. 1957a. “Jung on Film.” An Interview with Dr. Richard I. Evans, August 5-8, Zurich, Switzerland. Sehaller Films.

Jung, C.G. 1959. The Archetypes and the Collective Unconscious. Collected Works, vol. 9,1. Bollingen Series XX, Princeton, NJ: Princeton University Press.

Jung, C.G.. 1960. Synchronicity: An Acausal Connecting Principle. Collected Works, vol. 8, Bollingen Series XX. Princeton, NJ: Princeton UniversityPress.

Kuhn, T. 1962. The Structure of Scientific Revolutions. Chicago, Il.: University of Chicago Press.

Laszlo, E. 1993. The Creative Cosmos. Edinburgh: Floris Books.

Laszlo, E. 1999. The Interconnected Universe. Conceptual Foundations of Transdisciplinary Unified Theory. Singapore: World Scientific Publishing.

Laszlo, E. 2003. The Connectivity Hypothesis: Foundations of an Integral Science of Quantum, Cosmos, Life, and Consciousness. Albany, NY: State University of New York (SUNY) Press.

Laszlo, E. 2004a. “Cosmic Connectivity: Toward a Scientific Foundation for Transpersonal Consciousness.” International Journal of Transpersonal Studies, vol. 23.

Laszlo, E. 2004b. Science and the Akashic Field: An Integral Theory of Everything. Rochester, VT: Inner Traditions.

Kant, I. 1999. Critique of Pure Reason. Cambridge, MA: Cabridge University Press.

Kennell. J. H. and Klaus, M. 1998. “Parental Bonding: Recent Observations That Alter Perinatal Care.” Pediatrics in Review 19:4-2.

Klaus, M., Kennell, J. H. and Klaus, P.H. 1995. Bonding: Building the Foundations of Secure Attachment and Independence. Reading, MA: Addison Wesley.

Maxwell, G. 2011. “Archetype and Eternal Object: Jung, Whitehead, and the Return of Formal Causation.” Archai: The Journal of Archetypal Cosmology Volume 3 (Winter).

Mookerjee, A. and Khanna, M. 1977. The Tantric Way. London: Thames and Hudson.

Patanjali. 1990. The Yoga Sutras ofPatanjali (translated by Christopher Chapple and Yogi Ananda Viraj), Delhi: Sri Satguru Publications.

Quiring, John. 1996. “Transpersonal Psychology and Process Thought.” Process Perspectives 20:1 (Summer): 6-7.

Ring, K. and Cooper, S. 1999. Mindsight: Near-Death and Out-of-Body Experiences in the Blind. Palo Alto, CA: William James Center for Consciousness Studies.

Ring, K. and Valarino, E.E. 1998. Lessons from the Light: What We Can Learn from the Near-Death Experience. New York: Plenum Press.

Satir V. 1983. Conjoint family therapy. Palo Alto, CA: Science and Behavior Books.

Sullivan, H.S. 1953. The Interpersonal Theory of Psychiatry. New York: W. W. Norton.

Tarnas, R. 1993. The Passion of the Western Mind. Understanding the Ideas That Have Shaped Our World View. New York: Ballantine.

Tarnas, R. 1995. Prometheus the Awakener: An Essay on the Archetypal Meaning of the Planet Uranus. Woodstock, CT: Spring Publications.

Tarnas, R. 2006. Cosmos and Psyche: Intimations of a New Worldview. New York: Viking Press.

Tart, C.T. 1969. Altered States of Consciousness: A Book of Readings. New York: Wiley.

Teilhard de Chardin, P. 1975. The Human Phenomenon. New York: Harper and Row.

Tomatis, A. A. 1991. The Conscious Ear: My Life of Transformation through Listening. Barrytown, NY: Station Hill Press.

Vaughan, F. 1993. “Healing and Wholeness: Transpersonal Psychotherapy.” In: R. Walsh and F. Vaughan (eds) Paths Beyond Ego: The Transpersonal Vision. Los Angeles, CA: J.P. Tarcher, 160-165.

Whitehead, A.N. 1978. Process and Reality: An Essay In Cosmology: Gifford Lectures Delivered In the University of Edinburgh During the Session 1927–1928. Corrected Edition. Edited by David Ray Griffin and Donald W. Sherburne. New York: The Free Press.

Whitwell, G.E. 1999. “The Importance of Prenatal Sound and Music.” Journal of Prenatal and Perinatal Psychology and Health 13 (3-4), 255-262.

Wilber, K. 1980. The Atman Project. Wheaton, Il.: The Theosophical Publishing House.

Wilber, K. 1982. A Sociable God. New York: McGraw-Hill.

© 2012 Stanislav Grof

The Heretic

By Tim Doody

For decades, the U.S. government banned medical studies of the effects of LSD. But for one longtime elite researcher, the promise of mind-blowing revelations was just too tempting. This article has first been published by online magazine The Morning News on 26 July 2012.

At 9:30 in the morning, an architect and three senior scientists – two from Stanford, the other from Hewlett-Packard – donned eyeshades and earphones, sank into comfy couches, and waited for their government-approved dose of LSD to kick in. From across the suite and with no small amount of anticipation, Dr. James Fadiman spun the knobs of an impeccable sound system and unleashed Beethoven’s “Symphony No. 6 in F Major, Op. 68.” Then he stood by, ready to ease any concerns or discomfort.

For this particular experiment, the couched volunteers had each brought along three highly technical problems from their respective fields that they’d been unable to solve for at least several months. In approximately two hours, when the LSD became fully active, they were going to remove the eyeshades and earphones, and attempt to find some solutions. Fadiman and his team would monitor their efforts, insights, and output to determine if a relatively low dose of acid – 100 micrograms to be exact – enhanced their creativity.

It was the summer of ’66. And the morning was beginning like many others at the International Foundation for Advanced Study, an inconspicuously named, privately funded facility dedicated to psychedelic drug research, which was located, even less conspicuously, on the second floor of a shopping plaza in Menlo Park, Calif. However, this particular morning wasn’t going to go like so many others had during the preceding five years, when researchers at IFAS (pronounced “if-as”) had legally dispensed LSD. Though Fadiman can’t recall the exact date, this was the day, for him at least, that the music died. Or, perhaps more accurately for all parties involved in his creativity study, it was the day before.

At approximately 10 a.m., a courier delivered an express letter to the receptionist, who in turn quickly relayed it to Fadiman and the other researchers. They were to stop administering LSD, by order of the U.S. Food and Drug Administration. Effective immediately. Dozens of other private and university-affiliated institutions had received similar letters that day.

That research centers once were permitted to explore the further frontiers of consciousness seems surprising to those of us who came of age when a strongly enforced psychedelic prohibition was the norm. They seem not unlike the last generation of children’s playgrounds, mostly eradicated during the ’90s, that were higher and riskier than today’s soft-plastic labyrinths. (Interestingly, a growing number of child psychologists now defend these playgrounds, saying they provided kids with both thrills and profound life lessons that simply can’t be had close to the ground.)

When the FDA’s edict arrived, Fadiman was 27 years old, IFAS’s youngest researcher. He’d been a true believer in the gospel of psychedelics since 1961, when his old Harvard professor Richard Alpert (now Ram Dass) dosed him with psilocybin, the magic in the mushroom, at a Paris café. That day, his narrow, self-absorbed thinking had fallen away like old skin. People would live more harmoniously, he’d thought, if they could access this cosmic consciousness. Then and there he’d decided his calling would be to provide such access to others. He migrated to California (naturally) and teamed up with psychiatrists and seekers to explore how and if psychedelics in general – and LSD in particular – could safely augment psychotherapy, addiction treatment, creative endeavors, and spiritual growth. At Stanford University, he investigated this subject at length through a dissertation – which, of course, the government ban had just dead-ended.

Couldn’t they comprehend what was at stake? Fadiman was devastated and more than a little indignant. However, even if he’d wanted to resist the FDA’s moratorium on ideological grounds, practical matters made compliance impossible: Four people who’d never been on acid before were about to peak.

“I think we opened this tomorrow,” he said to his colleagues.

And so one orchestra after the next wove increasingly visual melodies around the men on the couch. Then shortly before noon, as arranged, they emerged from their cocoons and got to work.

Over the course of the preceding year, IFAS researchers had dosed a total of 22 other men for the creativity study, including a theoretical mathematician, an electronics engineer, a furniture designer, and a commercial artist. By including only those whose jobs involved the hard sciences (the lack of a single female participant says much about mid-century career options for women), they sought to examine the effects of LSD on both visionary and analytical thinking. Such a group offered an additional bonus: Anything they produced during the study would be subsequently scrutinized by departmental chairs, zoning boards, review panels, corporate clients, and the like, thus providing a real-world, unbiased yardstick for their results.

In surveys administered shortly after their LSD-enhanced creativity sessions, the study volunteers, some of the best and brightest in their fields, sounded like tripped-out neopagans at a backwoods gathering. Their minds, they said, had blossomed and contracted with the universe. They’d beheld irregular but clean geometrical patterns glistening into infinity, felt a rightness before solutions manifested, and even shapeshifted into relevant formulas, concepts, and raw materials.

But here’s the clincher. After their 5HT2A neural receptors simmered down, they remained firm: LSD absolutely had helped them solve their complex, seemingly intractable problems. And the establishment agreed. The 26 men unleashed a slew of widely embraced innovations shortly after their LSD experiences, including a mathematical theorem for NOR gate circuits, a conceptual model of a photon, a linear electron accelerator beam-steering device, a new design for the vibratory microtome, a technical improvement of the magnetic tape recorder, blueprints for a private residency and an arts-and-crafts shopping plaza, and a space probe experiment designed to measure solar properties. Fadiman and his colleagues published these jaw-dropping results and closed shop.

At a congressional subcommittee hearing that year, Sen. Robert F. Kennedy grilled FDA regulators about their ban on LSD studies: “Why, if they were worthwhile six months ago, why aren’t they worthwhile now?” For him, the ban was personal, too: His wife, Ethel, had received LSD-augmented therapy in Vancouver. “Perhaps to some extent we have lost sight of the fact that it” – Sen. Kennedy was referring specifically to LSD here – “can be very, very helpful in our society if used properly.”

His objection did nothing to slow the panic that surged through halls of government. The state of California outlawed LSD in the fall of 1966, and was followed in quick succession by numerous other states and then the federal government. In 1970, agents of the Drug Enforcement Administration released a comprehensive database in which they’d sorted commonly known drugs into categories, or schedules. “Schedule 1” drugs, which included LSD and psilocybin, have a “significant potential for abuse,” they said, and “no recognized medicinal value.” Because Schedule 1 drugs were seen as the most dangerous of the bunch, those who used, manufactured, bought, possessed, or distributed them were thought to be deserving of the harshest penalties.

By waging war on psychedelics and their aficionados, the U.S. government not only halted promising studies but also effectively shoved open discourse of these substances to the countercultural margins. And so conventional wisdom continues to argue that psychedelics offer one of a few possibilities: a psychotic break, a glimpse of God, or a visually stunning but fairly mindless journey. But no way would they help with practical, results-based thinking. (That’s what Ritalin is for, just ask any Ivy League undergrad.)

Still, intriguing hints suggest that, despite stigma and risk of incarceration, some of our better innovators continued to feed their heads – and society as a whole reaped the benefits. Francis Crick confessed that he was tripping the first time he envisioned the double helix. Steve Jobs called LSD “one of the two or three most important things” he’d experienced. And Bill Wilson claimed it helped to facilitate breakthroughs of a more soulful variety: Decades after co-founding Alcoholics Anonymous, he tried LSD, said it tuned him in to the same spiritual awareness that made sobriety possible, and pitched its therapeutic use – unsuccessfully – to the AA board. So perhaps the music never really died. Perhaps it’s more accurate to say instead that the music got much softer. And the ones who were still listening had to pretend they couldn’t hear anything at all.

On a Saturday last October, 45 years after dispensing those last legal doses, James Fadiman stood on stage inside the cavernous hall of Judson Memorial Church, a long-time downtown New York incubator of artistic, progressive, and even revolutionary movements. High above him on a window of stained glass, a golden band wrapped Escher-like enigmas around the Four Evangelists. Fadiman appeared far more earthly: wire frames, trim beard, dropped hairline, khakis, running shoes – like a policy wonk at a convention, right down to lanyard and nametag.

A couple hundred people sat before him in folding chairs and along the side aisles of the hall. He adjusted his head microphone, then scrolled his lecture notes and side-stepped the podium. He felt fortunate to be there for many reasons, he said, including a health scare he’d had a few months back – a rather advanced case of pericarditis. “Some of you, I know, have experimented with enough substances so that you’ve ‘died.’ But it’s different when you’re in the ER.” He chuckled. “And you’re not on anything.”

Most everybody laughed at his icebreaker, understood he was comparing, quite unfavorably, his recent experience to the way that, under the influence of high-dose psychedelics, one’s personality has a tendency to scatter like stardust. Which is to say that Fadiman was not addressing an ordinary audience.

He was the first presenter of the day at the fifth-annual Horizons, a weekend-long forum organized to “open a fresh dialogue” regarding the role of psychedelics in “medicine, culture, history, spirituality, and creativity.” The crowd consisted of young and old, dreadlocks and suits, crushed velvet and institutional bonafides. A self-declared prophet sat near Bellevue Hospital’s leading addictions specialist. Both are pro-psychedelics, though they differ on what qualifies as appropriate usage. Said addictions specialist is currently administering psilocybin to people with recurrent and advanced-stage cancer in – surprise! – a government-sanctioned study. Most people enrolled in his study have reported that a single psychedelic session substantially reduced their anxieties related to death, while also qualifying as one of their most spiritual experiences.

“I kind of did the squarest bio I could,” Fadiman said, pointing at a Horizons brochure, “just in case other people were reading it.” Who did he mean? Squares? Feds? He’d chosen to highlight his post-ban work, which sounded mildly interesting though fairly innocuous. Co-founder of the Institute for Transpersonal Psychology. Course instructor at San Francisco State, Brandeis, and Stanford. Writer. Member of various corporate boards. Don’t be fooled though. His bio obscures a well-documented notoriety.

In The Electric Kool-Aid Acid Test, Tom Wolfe writes about encountering “a young psychologist,” “Clifton Fadiman’s nephew, it turned out,” in the waiting room of the San Mateo County jail. Fadiman and his wife were “happily stuffing three I-Ching coins into some interminable dense volume of Oriental mysticism” that they planned to give Ken Kesey, the Prankster-in-Chief whom the FBI had just nabbed after eight months on the lam. Wolfe had been granted an interview with Kesey, and they wanted him to tell their friend about the hidden coins. During this difficult time, they explained, Kesey needed oracular advice.

Fadiman’s influence transcends counterculture, though. It might even stretch through the very medium through which you’re reading these words. In What the Dormouse Said, John Markoff reports that Fadiman had dosed and counseled numerous “heads” as they were attempting to amplify consciousness through silicon chips and virtual reality. The personal computer revolution, Markoff argues, flourished on the Left Coast precisely because of a peculiar confluence of scientists, dreamers, and drop-outs. And indeed, if you were to illustrate with a Venn diagram the relationships between those involved with Acid Test parties, the Homebrew Computer Club, the Augmented Human Intellect Research Center at Stanford University, Xerox’s Palo Alto Research Center, various backwoods communes, and, of course, the IFAS research center, you’d see an overlap of communities on the San Francisco Midpeninsula that just wasn’t available to the average IBM computer scientist in Westchester.

It’s true that Fadiman cooled it for several decades, did those square things in his bio, settled into the suburbs, and kept on the down-low any lingering passion for chemically boosted consciousness. But then, in 2010, with the publication of his book, The Psychedelic Explorer’s Guide: Safe, Therapeutic, and Sacred Journeys, it became official: At 70 years old, Fadiman had gone rogue. In a mild-mannered sort of way, yes, with charts, hypotheses, and a winning bedside manner. But government be damned, he was now an outspoken advocate for the careful but criminal use of psychedelics, especially LSD, his favorite.

What’s astounding isn’t so much that he came out of the psychedelic closet for a second time – most everyone retains a certain allegiance to their formative experiences – but that he is far from alone. And we’re not just talking about the tens of thousands of utopians who co-create an ephemeral Mecca in the swirling sands of Black Rock each summer.

Though draconian laws still keep psychedelics from the general public, next-generation administrators at the FDA and DEA have been approving research studies again. The taboo broke with a 1992 investigation of how dimethyltryptamine, or DMT, a fast-acting psychedelic, impacts consciousness; DMT wasn’t burdened by the cultural baggage of its three-lettered cousin. And what began quite haltingly had become, by the middle of the last decade, if not routine then certainly notable: Terminated research from the ’60s was being replicated and even furthered in dozens of studies by big-name players, including Johns Hopkins, NYU, and UCLA. These studies, which almost exclusively explore the psychotherapeutic potential of psychedelics (as opposed to, say, how they might influence creativity), are getting results that would make a Big Pharma rep salivate. Of the hundreds of volunteers who’ve participated, a high majority have said that psychedelics, given in a safe, supportive setting, helped them to, depending on the study, accept imminent mortality, overcome drug and alcohol addiction, mitigate obsessive-compulsive urges, or heal post-traumatic stress disorder.

Yet another study recently passed the approval process despite strong objections from the Pentagon: In the summer of 2011, 16 vets who returned from Iraq and Afghanistan with PTSD began receiving a combination of talk therapy and MDMA (pure Ecstasy). This, though the DEA still officially states that psychedelics’ “use in psychotherapy largely has been debunked.” The current relationship between regulators and these Schedule 1 substances is a tangle of impossible possibilities – not unlike the stained glass window overlooking Judson’s stage.

“What happens in serious psychedelic work,” Fadiman said to the people before him, “is there’s a sudden reframing of massive amounts of worldview. We don’t know much about what that learning means, but we sure can see the results.” Though he applauds the aforementioned studies, he has come to Horizons specifically to speak on their limitations. In fact, his entire lecture is intended to be an attack on what he calls “the medical model,” an approach to psychedelic drug use that curtails access to only a fraction of society, and for only narrowly defined goals centered around personal therapy.

Fadiman studied the people before him, then widened his eyes with faux innocence. “How many of you are going to be in a legal research study next year?”

No hands.

“Including not me. You not only have to be ill (to participate), but you have to be ill with something fairly awful. Now, how many of you are planning to have a psychedelic within the next year?”

An overwhelming majority of the audience raised a hand, some enthusiastic, others sheepish. Heads swiveled like periscopes, the better to see all those mea culpas.

“So, I’ll talk to you.”

Widespread laughter: score!

“For a long time after research stopped in the ’60s, I thought, ‘Oh, I can’t do the research that interests me the most, that’s the most life-changing, that has the most potential.’ I also realized that … what the government said is, ‘We are restricting some basic freedoms.’”

Throughout the lecture, his left hand poked like a conductor’s stick as he challenged his listeners with a series of questions.

“Can you go to most any group, from tea parties on one end, to us, I think we’re probably on the other, and say, is religious freedom something that we support in this country?”

“Is it all right to establish or re-establish or discover a connection to the Divine?”

“Is it OK to do something that leads to your own self-healing and improves your connection to the natural world?”

“Is it OK to discover how the universe works? At the moment, we’ve got two Nobel Prize winners who’ve copped to the fact of where they got their ideas.”

Francis Crick is one and the other: Kary Mullis, who was intermittently under the influence of LSD as he developed the polymerase chain reaction, a genetic sequencing technique through which scientists can detect certain infectious diseases, map the human genome, and trace ancestral heritage back thousands of years.

Fadiman was warming up now, standing tall for the 23 million Americans who, according to government stats, have already taken LSD, and the 400,000-plus who will try it for the first time this year. Curiosity continues to trump criminalization.

“We’re not necessarily going to be content if certain psychedelics are available on prescription (for people who are really ill),” Fadiman said. “That’s not what psychedelic freedom is about.”

Just as he began to speculate on how and when “psychedelic freedom” might be achieved, the microphone slipped off his ear, shoulder-bounced, and tumbled to the floor. It sounded like gunshots or a door being bashed in. Fadiman threw up his hands, fingers splayed, head lowered, as if a SWAT team was raiding the auditorium. He had the audience laughing again as a sound tech scrambled to make things right. Nonetheless, his slapstick evoked a sobering truth concerning the tenuous turf between personal and legal conviction. How many people here have ever been in an actual raid? Hands please?

The discovery of lysergic acid diethylamide, or LSD, is a fairly known tale, at least in certain circles. As war ravished Europe, Dr. Albert Hofmann hunkered down in his lab in Basel, Switzerland, and synthesized dozens of compounds from ergot, a grain-attacking fungus, in an effort to create a medicinal blood stimulator. In 1943, he accidentally (or, as he has claimed, synchronistically) absorbed a few potent drops from the 25th variety, soon thereafter experiencing a “not unpleasant intoxicated-like condition” that dramatically altered his bicycle ride home.

What’s less commonly known, even in certain circles, is what should or shouldn’t be done with this potent discovery, which Hofmann has referred to as “my problem child.” During a second, entirely intentional exposure, his problem child unleashed upon him a slew of hellish and terrifying visions, severely compromising both his short-term sanity and his ability to navigate the physical world.

Through his re-stabilized head microphone, Fadiman was focusing on exactly these sorts of dangers: He’d transitioned from advocacy to shop talk. “Have you ever had a bad trip?” he asked the audience. “Hands please. That’s quite a few. Do you know why it was a bad trip? Unfortunately, less hands.”

Of his own hands: The right clutched lecture notes, while the left danced. “OK, you aren’t going to be involved in research studies. But in your personal lives you are going to be looking at” – left ascending three invisible steps – “yourself, science, and the Divine. And so it’s important to know, what is necessary for the safest, most successful, and potentially sacred experience?” Palm upward. “The answer is, very simply, six items.” And then down to the podium.

These six items are, perhaps simply enough, factors that Fadiman believes determine the quality of a psychedelic experience, as well as its specific nature. He has culled them from his work with hundreds of people in therapy sessions, creativity experiments, and Death Valley vision quests. They are:

Set: the mental attitude of a would-be psychedelic voyager
Setting: the surroundings in which a psychedelic substance is ingested
Guide: a person experienced with non-ordinary states of consciousness who helps to mitigate challenges and channel insights
Substance: the type and quantity of psychedelic agent
Session: the entirety of a psychedelic trip, including all activities or rituals
Situation: the environment, people, and culture from which a person comes to a session and returns afterward

Regardless of whether they use Fadiman’s preferred terminology, medical researchers conducting government-approved therapeutic studies look for these same essential parameters, as do shamans and tribal elders across the globe. These diverse facilitators of psychedelic experiences carefully screen applicants to ensure they are of sound(-enough) mind and prime them on the benefits that a session can offer, thereby helping to focus intentions, establish positive expectations, and dramatically increase the odds of a favorable outcome.

Sessions typically occur in a comfortable, often enchanting, environment – say, a star-shaped temple in the Brazilian Amazon or a cushy, made-over hospital room at NYU’s dental school. And in these settings, therapists, shamans, and researchers follow a certain protocol, comprised of time-tested, peer-reviewed rituals that have been shown to most effectively channel revelatory and even, as Fadiman would have it, sacred, experiences. A psychedelic voyager may be guided with singing and drumming, or with prerecorded non-lyrical music, eyeshades, and photographs of loved ones, or with suggestions, observations, and questions, and, sometimes, later in the session, as the potency of a substance wanes, with forays into particularly choice habitat. Afterwards, the voyager is welcomed back and assisted with integrating into her situation any learning, insights, and mystical flashes that may have occurred.

Those least likely to account for these six factors are typically people with less stable personalities, which is to say, youth. Which is to say, most of us who found ourselves with LSD on our tongues for the first time in a friend’s basement, at a jumping party, or on the untamed outskirts of sprawl. The mind might be entirely unprepared, the dosage too much, the setting and lack of effective support quite dangerous.

“I think guides are wonderful,” Fadiman said, “which often gets me dismissed as a radical conservative – a kind of fun thing to be in this crowd. But look, you don’t go to the airport and say, ‘I want to fly a plane.’ And a pilot says, ‘Here’s the keys, pick one of those, and give it a shot.’”

He has a point. After all, even the most positive LSD experiences often involve disturbing visions and moments of paranoia. Most of us still managed to do OK during our first time, maybe even were steered toward an epiphany. But some of us didn’t. Some of us crash-landed and injured ourselves or others, or were overpowered by unresolved subconscious conflicts, or, in extremely rare cases, unleashed a latent psychosis. Over the last 50 years, more than a few were locked up in a correctional facility of one kind or another and injected with Thorazine, which, unfortunately, has a way of transforming a drug-induced freakout into life-long affliction. (Xanax is a far better option.) Acid casualties from the 1960s still haunt Telegraph Avenue like ghosts with unsettled scores.

When Fadiman sat down to write his book, he had at first been attempting to write a memoir; after an early draft, he decided he was doing too much navel-gazing and shifted his style and content to create The Psychedelic Explorer’s Guide, which reads a good deal like a how-to-manual. Still, he didn’t entirely suppress his initial urge to tell portions of his own tale, and why should he? Even as he conducted government-sanctioned research, he was cavorting with mystics, poets, outlaws, and a pistol-packing man who transnationally distributed LSD, regularly communicated with U.S. intelligence agencies, and pioneered procedures for psychedelic sessions that highly regarded medical facilities still use today.

In one anecdote that made the cut, he recounts a night spent with Ken Kesey on a feral embankment between the shoreline and the town dump of sleepy Pescadaro, California. Peaking on a relatively high dose of LSD shortly before dawn, Dorothy, one of Ken’s girlfriends, lay down in the dirt to better observe one particular wild violet. Stardust waltzed off its purple petals into the embankment, the ocean, even the dump. Stranger still, the violet budded, blossomed, withered, and died, both forward in time and in reverse.

When Dorothy tried to explain it all to James, he didn’t scoff. Instead he got down beside her and, utilizing insights he’d developed as an IFAS guide, urged her deeper into the experience. Dorothy became aware that stardust was also coursing through her neural network. The universe wasn’t random chance, she thought that morning, but ebullient choice. She didn’t need to go anywhere because she was everywhere.

If you ask her today, she’ll tell you the effects from her trip lasted long after she came down. For starters, she’d say, this was the pivotal moment that led her to become a filmmaker. (Her short documentaries have earned numerous accolades, including an Emmy, an Oscar nomination, and the Corporation for Public Broadcasting Gold Medal.) But, she’d add, that’s not all. That morning, she ditched Hunky Ken for Interstellar James, and for 47 years and counting, they’ve lived together in an open marriage.

What happened to Dorothy Fadiman that morning? How about Francis Crick and the people with cancer in the anxiety studies? Staunch materialists might argue that exogenous, psychotropic molecules had simply transformed their three pounds of gelatinous gray head muscle into funhouses for a few hours. But Ms. Fadiman, Crick, and most study volunteers say something quite different – that the psychedelics they ingested acted as a sort of antenna, allowing them to receive rather profound transmissions that they couldn’t typically access during their ordinary states of consciousness. Such a claim is not without precedent.

Ever since people first altered their surroundings with celestially aligned rocks, they’ve also been altering their inner landscapes. Though Albert Hofmann’s recipe is entirely modern, tribes and other pre-industrial societies from Australia to Mesopotamia have long been mixing the medicine into brews, snuffs, and powders. In rituals, often of a collective nature, they’ve ingested these substances and then sung, drummed, and channeled to access insights, archetypal beings, and alternate realities. While these societies are as eclectic as orchids, they share at least one characteristic: Their rituals have served as an axis mundi, a psychic compass that simultaneously situates and provides direction to both individual and community. As a result, matter and consciousness are experienced as entwined, purposeful, and sacred.

On stage and page, Fadiman has argued that, in marked contrast, most members of post-industrial societies perceive themselves as happenstance cogs in a clockwork universe, and consequently, exhibit a profound and increasingly dangerous alienation. The dissociation of self is so fundamental that bioregions are sub-divided into tract housing, resources into quarterly earnings, and people into one-percenters and the rest. For Fadiman at least, even traditional Western therapy, which seeks to re-align a sick individual to this worldview, must necessarily end in a cul-de-sac.

Marlene Dobkin de Rios, a medical anthropologist, has argued that there is a strong correlation between centralized power and psychedelic prohibition as authoritarian leaders have perennially associated these substances with insurrectionary tendencies. Indeed, whether in 17th-century Europe or 19th-century America, even as proponents of church and state enclosed communal lands and subjugated the inhabitants therein, they especially targeted those deemed most resistant to ideological control – the shamans, witches, magi, occultists, and others who concocted, imbibed, and distributed psychedelic substances, and believed themselves to be in an ongoing discourse with land, non-human species, and spirits.

The !Kung (tongue-click then “kung”) is one of the psychedelically-augmented, anarchistic societies that had survived these purges well into contemporary times. A nomadic people, they’d harmonized with the austere rhythms of the Kalahari Desert for thousands of years. Elizabeth Marshall Thomas, who lived with them during the 1950s, writes that the !Kung recognized an illness called “Star Sickness,” which could overcome members of the community with a force not unlike gravity and cause profound disorientation. Unable to situate themselves in the cosmos in a meaningful way, the afflicted displayed jealousy, hostility, and a marked incapacity for gift-giving – the very symptoms that plague many Westerners, according to Fadiman (and, certainly, quite a few others).

To cure and prevent Star Sickness, the !Kung conducted all-night trance dances around a bonfire four times per month on average, often augmenting them with psychoactive plants including dagga (marijuana) and gaise noru noru (more than marijuana). As dancers sang, stomped, shook rattles, and spun, a boiling force called n/um collected in their abdomens and sometimes flowed out through their heads, causing them to soar over fantastical terrain. These grand vistas were said to provide the necessary perspective to re-align community members both to the stars and one other.

Surely, the !Kung’s chosen mode of governance reflected these regularly-scheduled astral tune-ups. Until the 1970s, when apartheid-era colonizers irrevocably altered the flora, fauna, and flow of the Kalahari, the !Kung had organized through leaderless, consensus-based decision-making, coupled with a bawdy humor that infused even the most sacred moments to dispel tension and check the power-hungry. This sort of power-sharing sounds not dissimilar to what Occupy Wall Street protesters attempted last year with their General Assemblies and Spokes Councils. Perhaps both Occupiers and the !Kung have tapped something primordial: When researchers isolate heart cells on a Petri dish, the cells bounce to their own idiosyncratic rhythms. But placed beside one another, they self-organize into a collective beat.

The urge to connect with the numinous remains strong throughout the world, including the West – even as medical experts pathologize it, monotheistic bureaucrats neuter it, and Madison Avenue spellcasters exploit it. Of course psychoactive plants, fungi, and synthetics aren’t the only way to sate this urge: Sufis spin, musicians riff, and physicists formulate. And sometimes psychedelics just get in the way, according to religious scholar Huston Smith.

After surveying late-’60s counterculture, he warned that without the grounding of long-term spiritual practice, psychedelic drug use amounts to, at best, a “religion of religious experience,” a series of mystical wows decontextualized from personal and community health.

Notably, though, the plant teachers – as some shamans refer to vision-inducing flora – have been perceived by what probably amounts to a majority of human societies as a legitimate and particularly effective portal into the fabric and meaning of reality. Michael Pollan popularized what ethnobotanists have been saying for some time with his 2001 book, The Botany of Desire: Plants and people have been involved in a symbiotic relationship for millennia. They entice our noses, bellies, and brains; we nurture their terrain. It’s a fairly open secret that not only does the Amazon contain the necessary ingredients for ayahuasca, one of the strongest and oldest psychedelic brews, but that the forest itself isn’t so much a wilderness as a 10,000-year-old garden under indigenous management.

By comparison, Americans commonly perceive the wild violet as a noxious weed – though it’s a rich source of Vitamins A and C, as well as antimicrobial and anti-HIV agents. The wild violet is quite hardy, too, which is why Dorothy Fadiman’s prized flower was able to flourish near the Pescadaro dump, the ass-end of civilization. But for homeowners intent on turning their parcel of property into a monochromatic green sheet, that simply means repeated applications of a particularly strong herbicide along with, as one website advises, “persistence.” Such an approach to land use, which views private property as so inviolable and autonomous that it’s above even the laws of nature, surely reflects how many Americans perceive not only their surroundings but also themselves. You’ve heard the one about the rugged, entirely self-made individual?

Albert Einstein, who navigated the twilight turf between consciousness and matter for much of his life, argued that “Man” suffers from an “optical delusion of consciousness” as he “experiences himself, his thoughts and feelings as something separated from the rest.” His cure? Get some n/um. “The most beautiful thing we can experience is the mysterious,” he said. “It is the source of all true art and science. He to whom this emotion is a stranger, who can no longer pause to wonder and stand rapt in awe, is as good as dead: His eyes are closed.”

Though scientists are more typically seen as killers of myth, not its creators, Einstein and many of his more visionary contemporaries sound as trippy as any of yesterday’s mystics. They say that the time-space continuum warps like the surface of a trampoline. They say that we are stardust. That there is no “in the beginning.” That things are not things at all, but relations. That the observer tweaks the observed, at least on a sub-atomic level, just by observing.

Who knows, their latest findings may one day affirm some ancient hypotheses. If reality isn’t shaped with the psychically aware, self-organizing units that Giordano Bruno called monads in the sixteenth century, then perhaps it’s woven with Indra’s net, the jeweled nodes of which stretch into infinity, each one a reflection of all others. To entertain such ontologies is to re-contextualize one’s self as a marvelous conduit in a timeless whole, through which molecules and meaning flow, from nebulae to neurons and back again. If certain of these molecules connect with our serotonin receptors like a key in a pin tumbler, and open a door to extraordinary vistas, why shouldn’t we peek?

Fadiman had another question for the audience: “How many of you have heard about micro-dosing?” He adjusted his bifocals to a groovy sight: two-dozen uplifted hands. “Whoa!”

Despite the 45-year government ban, Fadiman had never stopped longing to tinker with LSD, to catalogue what we might be capable of with this byproduct of mold. Of all the possible forays into this psychic terra incognito, he was most eager to explore micro-dosing – specifically its long-term effects. And he didn’t have another 45 years for the feds to get hip to the plan.

Fadiman claims the “normal range” of an LSD dose varies, based on whether one is seeking a recreational experience (50 mcg), creative boost (100 mcg), therapeutic session (100-250 mcg) or face-to-face with “the Divine” (400 mcg). But, he cautions, a higher dose is a riskier dose.

First things first: Fadiman defines a micro-dose as 10 micrograms of LSD (or one-fifth the usual dose of mushrooms). Because he cannot set up perfect lab conditions due to the likelihood of criminal prosecution, he has instead crafted a study in which volunteers self-administer and self-report. Which means that they must acquire their own supply of the Schedule 1 drug and separate a standard hit of 50 to 100 micrograms into micro-doses. (Hint: LSD is entirely water-soluble.)

Beginning in 2010, an unspecified but growing number of volunteers have taken a micro-dose every third day, while conducting their typical daily routines and maintaining logbooks of their observations. Study enrollment may last for several weeks or longer: There doesn’t appear to be a brightly drawn finish line. After several weeks (or, um…), participants send their logbooks to an email address on Fadiman’s personal website, preferably accompanied by a summary of their overall impressions.

“Micro-dosing turns out to be a totally different world,” Fadiman extolled. “As someone said, the rocks don’t glow, even a little bit. But what many people are reporting is, at the end of the day, they say, ‘That was a really good day.’ You know, that kind of day when things kind of work. You’re doing a task you normally couldn’t stand for two hours, but you do it for three or four. You eat properly. Maybe you do one more set of reps. Just a good day. That seems to be what we’re discovering.”

Elsewhere Fadiman has been more specific about the logbooks he’s received. One physician reported that micro-dosing got him “in touch with a deep place of ease and beauty.” A vocalist said she could better hear and channel music. In general, study participants functioned normally in their work and relationships, Fadiman has said, but with increased focus, creativity, and emotional clarity. Until he releases his data archive in a comprehensive manner, it is, of course, not possible to scrutinize the validity of his claim.

Perhaps the micro-dose study offers Fadiman the opportunity to follow the recommendation of a longtime, now-deceased friend, Albert Hofmann, who, according to Fadiman, called micro-dosing “the most under-researched area of psychedelics.” Word on the street is that Hofmann had also surmised that micro-doses of LSD would be a viable market alternative to Ritalin. It’s an intriguing claim. After all, if Fadiman had administered Ritalin to the scientists in his creativity study, they might have focused on their problems just as intently as they had on LSD, but they probably wouldn’t have had as many breakthroughs. Even as Ritalin boosts attention, it has a tendency to create tunnel vision, which, more often than not, stymies imagination.

“I just got a report from someone who did this for six weeks,” Fadiman said. “And his question to me was, ‘Is there any reason to stop?’” More laughter throughout the hall, another adjustment of bifocals.

Is Fadiman reckless, irresponsible, a mad corrupter of youth? Most of today’s politicians, law enforcement officials, cable news hosts, and medical practitioners – whom, collectively, Fadiman might refer to as “the establishment” – would undoubtedly level these charges and more against him if only they knew of his research. But these sorts of accusations have long been aimed at those who posit opinions so dissident that, if taken seriously, they threaten not just how society operates, but, perhaps more fundamentally disturbing to both reigning authorities and the general public, how we perceive ourselves.

Regardless of whether heretics are visionaries, cranks, or people to whom both labels apply, if their ideas have a certain traction, the powers that be – aka establishments throughout the ages – attempt to silence them through exile, thumbscrews, the stake, incarceration, public ridicule, etc. Such tactics are terribly effective. Which is to say that most accused heretics suffer and are forgotten. But not always. Every once in a while, posthumously or otherwise, one of them topples a paradigm.

During an afternoon break, a handful of younger Horizons attendees – dressed, to greater and lesser effect, in daring colors and cuts – clumped together on the front stairs of Judson Church and worked through the logistics of micro-dosing. No scale required, they said. Paper blotter, Pez, whatever, just plop it in a water bottle, draw some ticks on the side. A little trial and error of course, but do mind the chlorine.

Occupy Wall Street protestors streamed by, sleep-deprived, scruffy, grinning, keffiyehs knotted around necks; several held aloft a golden bull, “FALSE IDOL” painted on its flanks. They were rallying across the street in Washington Square Park before attempting an evening takeover of Times Square, on this, the 29th day after sleeping bags were first planted in the Financial District. Heavily armored police surrounded them and covertly amassed on adjacent streets where the media cameras weren’t focused. “We are unstoppable!” a thousand Occupiers chanted. “Another world is possible!”

History has proven the fallibility of their first line. But as to their second? For starters, this other world depends on visioning at least as much as active resistance, and that’s where, historically, psychedelics come in. Long before the mathematicians and scientists in Fadiman’s creativity study utilized LSD to better envision formulas, materials, and the interstices between, traditional societies tripped to comprehend and commune with people, animals, plants, bioregions, and the spirits they felt moved through all things.

Which brings us to the next point: It’s not just one world that is possible, but many. The American Psychiatric Association could recognize Star Sickness as a pathology. The U.S. government could tether progress to Gross National Happiness as is done in Bhutan, or follow the lead of Evo Morales, Bolivia’s first indigenous leader, and implement the Law of Mother Earth, so that “the balance of ecosystems and local inhabitant communities” are granted the legal right “to not be affected by mega-infrastructure and development projects.” Many enlightening policies emanate from societies like the above, where non-ordinary states of consciousness are prized.

If these ideas seem far out to you, that’s precisely the problem. Or so thought Einstein. Capitalism, he argued, simultaneously creates a “huge community of producers” who are “unceasingly striving to deprive each other of the fruits of their collective labor” and an “oligarchy” that “cannot be effectively checked even by a democratically organized society.” He believes this subjugation is largely accomplished “not by force” but because “the privileged class” had long ago established a “system of values by which the people were thenceforth, to a large extent unconsciously, guided in their social behavior.”

In other words, cops don’t just hide on side streets – they sneak into heads, too. And so Mitt Romney, the Republican presidential hopeful, can declare with patrician matter-of-factness, “Corporations are people, my friend.” He’s absolutely correct, too, as far as U.S. law is concerned. Corporations have the rights that bioregions don’t. And they have far better legal representation than you.

We’re always evolving, one way or another, as we play for keeps on what William James called the “field of consciousness.” While countless questions remain as to the parameters of this field, one thing is certain. Fadiman and his far-flung colleagues have provided the means through which contemporary Westerners can visit areas once thought to be out-of-bounds, or accessible only to a select few, through divine grace, a near-death experience, or 10,000 hours of meditation. Under the right circumstances, these psychic dérives are far less dangerous than, say, a lunar landing, and may ultimately prove as rewarding, if not more so.

So then, why the hysteria?

It’s a question Fadiman asks and attempts to answer. “Why did our drug research frighten the establishment so profoundly? Why does it still frighten them?” he writes. “Perhaps because we were able to step off (or were tossed off) the treadmill of daily stuff and saw the whole system of life-death-life. We had discovered that love is the fundamental energy of the universe. And we wouldn’t shut up about it.”

At first glance (and maybe second and third), his answer may sound maddeningly, well, Californian. But that doesn’t mean he’s not onto something. After all, to experience self and surroundings as entwined and enchanted, which those engaged in a guided psychedelic session have a statistically significant chance of doing, is to extend the very definition of self outward, so that one is far more apt to behave like heart cells. Jesus is said to have overturned moneychangers’ tables in the name of sacred turf. Just imagine what a critical mass of formerly upright citizens might do if they suddenly saw the whole earth as a temple. “No wonder,” Fadiman writes, “enlightenment is always a crime.

© Tim Doody – publishes with kind permission

Rekindling the Entheogenic Light

By Terence McKenna

1998 marks the Twentieth Anniversary of the first publication of The Road to Eleusis. Twenty years is long enough for a child or an idea to reach the threshold of maturity. The ideas which the authors – the banker, the chemist and the classicist – brought forth have been largely unchallenged and ignored by specialists in the culture of ancient and Classical Greece. The situation seems to fulfill the rule of thumb that when ideas are controversial they are discussed, when they are revolutionary, they are ignored.

And without contest the ideas put forth by this unlikely threesome are revolutionary indeed. But why? Of what possible import could the methods and materials of a dead mystery cult hold for this world of the third millennium? The answer is simply this: that how we understand and explain to ourselves what transpired at Eleusis determines in large measure our spiritual values and our relationship to the dark uncharted vastness of the entheogenically illuminated mind. The extinction of the cult at Eleusis was a small part of the tumult and turmoil that gripped the Ancient World as its syncretic and celebratory polytheism was harried and hunted to extinction by hate-crazed mobs acting in the name of their Prince of Peace. Let us not pass over the fact that Aleric the Visigoth, the destroyer of Eleusis and much else of the Ancient World, was a thoroughly Christian as he was barbarian.

Often in my mind’s eye, I have visited that evil day when the dark smoke of rape and pillage defiled the blue of the Attic sky, and the ominous standard of the crow, insignia of this barbarian chieftain, fluttered and snapped in the sullied air, a mute witness to history shaping atrocity. It was a day of unthinkable acts; the Telesterion breached, the priesthood shattered, the sacred lineage terminated by murder and diaspora. If there are truly pivotal moments in human history, then this surely was one of them. For as the authors of The Road to Eleusis make clear, the day before that day of rampage was the last sane moment that Western man was to know for nearly 1500 years. The destruction of Eleusis cut the umbilical cord of the developing Western mind, severed its connection to the great mysteries of the earth mother/Great Goddess and the still more ancient cults of Crete with its connections further south and deeper into time, to the bedrock of the African genesis of consciousness and ecstasy in our newly evolved species.

And one can wonder: What if the fates had seen fit to allow another ending? What if the horrifying cult of the Gallilean had not insinuated its way into dominance of Roman civilization? What if late Roman Christianity had not been allowed to hunt its critics into extinction and to infect the whole polity of Europe with its necrophilia and self hate? The true poignancy of the situation can only be felt by those who agree with the premise of this book, that Eleusis was the last redoubt of entheogen based religious spirituality in the West. With the destruction of Eleusis the connection to the Earth mother Ge, the Gaian Logos was severed and the stage was set for the descent into mass pathology that reached its Apocalyptic crescendo in the rise of the modern industrial state and its use of propaganda and the threat of nuclear annihilation to pursue its agenda.

On a particular weekend some several decades ago, as the Jewish inhabitants of the Warsaw ghetto were being systematically murdered like rats in a sewer by a particularly virulent expression of the Western mind; the Wehrmacht acting at the behest of the German National Socialism, a Swiss pharmaceutical chemist made a remarkable discovery. Unaware that just a few hundred miles away from his quiet laboratory was unfolding a situation whose horror would come to epitomize the mindless self devouring psychosis of Twentieth Century politics, Albert Hofmann self-administered lysergic acid diethylamide and began his famously unsteady bicycle ride through the streets of Basel.

Hofmann himself, would doubtless, in that moment, have been amazed if anyone had suggested to him that his lysergic epiphany had any relationship at all to the horror then unfolding in Poland, or to the extinction of a nearly forgotten Greek mystery cult centuries ago.

However now, and with the superior wisdom of hindsight, we see that these disparate events in time and space were all part of the unfolding drama of the evolution of he human soul and its struggle with the primal darkness that attended its birth like a placenta.

For we have been lost for some time, Monotheism, scientific reductionism, materialism and mass marketing have built a world unfit for fools, let alone the rest of us. Our culture which denies spirit, femininity, ambiguity, Eros and fun and offers in its place debt, alienation, and debauchery is a daily perceived as more and more inadequate by more and more people. And the answer to this dilemma is clear; we require a radical reintegration with the living mystery, both individually and collectively. This encounter is the sine qua non for setting a new course toward sanity, balance with the earth and true community. These values are only to be recovered through a rebirth of the mysteries and a reconnection with the numinous. This is most effectively and easily achieved through the use of entheogens, those same sacraments that flourished at Eleusis and that today excite the agendas of pharmaphobes and crypto fascists.

Quite simply we need to change our minds. Quickly. And nothing is capable of changing our minds as gently and effectively and rapidly as the entheogens have been shown to do. They are the medicine we need, they are our ancient birthright, denied us the thin lipped heresy hunters ever on the lookout for competitors to their own miserably eviscerated Eucharist. The discoveries described by the authors of this book hint at a return to a world of experience that is authentically human. For this alone we owe these authors a debt of enormous gratitude. Their lives and work have rekindled the entheogenic light so brutally extinguished at Eleusis. Because of their scholarship and discoveries there is an iota more of hope in this troubled world. This cannot be a bad thing.

Thirty Years of Psychedelic Research

The Spring Grove Experiment and its Sequels
By Richard Yensen, PhD and Donna Dryer, MD, MPh

In the late 1960′s a multi-million dollar interdisciplinary research center opened in the State of Maryland. This center for psychiatric research was a consequence of research in psychedelic psychotherapy performed by Albert Kurland and his associates at the Spring Grove State Hospital. Though the studies at Spring Grove State Hospital and those that followed at the Maryland Psychiatric Research Center (MPRC) ended in 1976, they remain the largest, most sustained and systematic study of psychedelic drugs and psychotherapy yet attempted.

This article emerged from a dialogue between the authors. We were doing a retrospective analysis of the Spring Grove research before designing our own study, one that we hope will advance this tradition (Yensen, Dryer & Kurland, 1991). We reviewed the studies done at the Spring Grove State Hospital and the Maryland Psychiatric Research Center asking the following questions: 1) Why did some studies have such good results and others such equivocal ones? 2) What mistakes occurred that future researchers in this area might avoid? 3) The research team used statistical assessment and double-blind controlled studies. This approach is the accepted standard method for studying psychoactive compounds. Is this methodology appropriate and sufficient to study psychedelic medicines?

Our analysis of the above questions is separated into five themes: 1) A discussion of the evolution of the therapeutic paradigms used in the studies. 2) An analysis of the political and interpersonal contexts affecting the research. 3) A description of the major studies conducted at Spring Grove State Hospital and the MPRC highlighting the methodological issues. 4) A survey of the non-drug therapies that evolved from the psychedelic research. 5) The current status of research and possible future directions for psychedelic research.

Spring Grove State Hospital
Early observations

Our group’s research with psychedelic drugs began with LSD in the early 1950′s. The first study at Spring Grove State Hospital was an attempt to characterize the effects of LSD upon hospitalized, chronic schizophrenics. Four patients received one hundred micrograms (100 µgrams) administered daily in a single intramuscular injection for fourteen (14) days. The initially marked changes in behavior diminished rapidly with little or no response noted after the second dose.

In order to study the unusually rapid tolerance the experimenters varied the drug free interval and observed that after five drug free days a strong reaction would occur. At four days some patients showed a mild reaction, but not the equal of the first day. After six drug free days a reaction as strong as that on the first day was observed.

In an attempt to overcome the tolerance exhibited by these four patients, dosage was increased by 100 µg daily. Every patient would receive 100 µg on day one, 200 µg on day two and 300µg on day three, up to 500 µg. This regimen yielded a response on the first day, a slight response on the second day, no response on days three and four, and a very questionable response on the fifth day. Five hundred micrograms (500 µg) was the maximum dose used.

Cross-tolerance with various LSD derivatives was tested. Cross tolerance was noted with LAE and brom-lysergic acid. On the theory that what appeared to be physiological cross tolerance might be psychological in nature (that the patients were just becoming adjusted to the psychological effects of LSD) the experimenters alternated LSD and mescaline HCl 1. There was no cross tolerance between LSD and mescaline HCl 2.

This initial descriptive and naturalistic study came to include twenty (20) schizophrenics in the various regimens of LSD administration. Important conclusionsq from this study included the realization that it is impossible to administer LSD in a double blind fashion. Although LSD was administered in double blind fashion at first, both experimenters and hospital staff were aware which patients received LSD within an hour of drug administration.. The authors suggested that the hallucinations induced by LSD might have value for helping therapists understand the underlying dynamics of a patient’s psychopathology. One can also observe in retrospect the powerful effect of the then new and now almost universally accepted paradigm of the psychoactive drug. This way of thinking about pharmacological substances and their effects on humans was defined by early major neuroleptic drugs like Thorazine and Reserpine. The basic assumptions that indirectly guided this research included the conjecture that LSD could be given on a daily basis to patients in order to produce a chemotherapeutic effect as with other psychiatric drugs. It was assumed that the effects of LSD could be adequately observed and understood by trained clinicians not directly involved with the patient’s treatment, who had no prior relationship with the patient. In summary the expectations were for LSD to be a drug like any of the other known psychoactive drugs. The results were startling, inexplicable and unexpected:

One catatonic patient who had been mute for some years suddenly burst out into loud wailing sobs which were shortly followed by overwhelming bursts of laughter starting 35 minutes after the drug was given. This patient seemed most distressed and shaken. Intermittently she would open her mouth as if she were trying desperately to talk or at least to exercise the muscles of her mouth. She also expressed a state of acute anguish with her body movements. When asked why she was crying, she said, “You should never leave the farm.” A half hour after the crying started, the wails seemed to end in a giggle. Soon the tears diminished, and she had almost continuous waves of laughing for another hour or so. The patient then began to walk about the ward studying the walls and windows as though she were seeing them for the first time. She seemed to respond to hallucinations, for she began to talk to non present individuals. Every few moments for the next few hours she would shake with laughter, and then she might talk a little. Her speech was never particularly coherent, and she soon became preoccupied with the fact that something or somebody was tickling her. She often said she enjoyed things very much and that this was a nice ward, etc.
Three hours after the drug was given, the patient was prancing about the ward and still bursting into gales of laughter. She could hardly eat since she said she had no appetite. That afternoon she played basketball for the first time since she was admitted to the hospital although the opportunity had been offered to her many times. She seemed interested in the effort and was pleased at her attempts. She walked about briskly, smiling broadly, and occasionally laughing. That evening she went to a dance and danced with another patient for the first time. She continued talking until bedtime. the next morning when she awoke, she was her old catatonic self, unable to speak, unable to show interest in anything about her, and quite withdrawn.
On this day the patient received another injection. She laughed a little at first, spoke few words, but a few hours later lapsed into her previous mute and withdrawn behavior. Thus on the second day we had slight evidence of change from her previous behavior, however much less than the change observed on the first day the drug was given.
When the patient received the same dosage the third morning, she showed no response at all (Cholden et al., 1955, pp. 213 & 217).

Observations like these helped the team to realize that this drug was unlike other psychoactive medications because of its unique combination of dramatic alterations in consciousness, profound psychodynamic action as well as the rapid building of tolerance. They realized that this combination of effects required a trained clinician with a well established relationship to the patient in order to understand, correctly describe and appreciate the dynamics of this complex situation (Cholden, Savage & Kurland, 1955).

After this rudimentary work there was a chronological gap in the research at Spring Grove State Hospital. Dr. Kurland involved himself in the study of other psychoactive medications. Charles Savage trained as a psychoanalyst and pursued his career as a psychedelic researcher in California at the Institute for Advanced Study.

Spring Grove State Hospital—Cottage 13
A humble beginning

During the late 1950′s and early 1960′s a young psychologist, Sanford Unger, began collaborating with Albert Kurland and suggested the renewed pursuit of psychedelic research. Unger had contact with the team at Hollywood Hospital in Vancouver, British Columbia, where work was in progress using a psychedelic approach in the therapy of alcoholism. The therapy involved administration of a single overwhelming high dose of LSD (400-800 µgrams) within a specially structured environment of expectations and stimuli designed to foster a mystical experience (Stace, 1960; Pahnke, 1963). By then the researchers were aware that the experiential roots of this approach were shamanistic, it seemed to offer a convenient, short, and intense therapy—a pragmatic vehicle for studying scientifically the effects of psychedelic substances as adjuncts to psychotherapy.

The project at Spring Grove began in 1963. A modest cottage on the hospital grounds housed the small research team. It is important to note here that the facilities were unpretentious and unobtrusively integrated into the overall facility of Spring Grove State Hospital. This hospital is one of the oldest mental hospitals in the United States. At the time Spring Grove was well-known for its progressive treatment. Cottage thirteen was a white clapboard two story cottage with four rooms and a bath on each floor. Two rooms were outfitted with sound systems and designated as treatment rooms for the psychedelic drug sessions.

The atmosphere was earnestly optimistic. The clinical staff of the State Hospital collaborated in the selection and support of patients undergoing the new therapy. The natural expectation was that in time they would be trained to use this exciting and dramatically effective new treatment. The sense of enthusiasm, confidence and hope was contagious. A devoted team from the State Hospital Alcoholic Rehabilitation Unit affirmed the work with LSD totally. Although in the early work a no treatment group was proposed as a control group, these plans had to be abandoned. Both the patients and the staff of the State Hospital saw the psychedelic treatment as so valuable and effective that they adamantly objected to withholding the treatment from any patient who qualified for it on ethical and humanitarian grounds. The research team acceded to these demands in a decision that preserved morale and working alliance while sacrificing scientific precision (Unger, 1969; Kurland et al., 1966 & 1967).

The research with alcoholics grew from a pilot phase of open clinical trials to double-blind trials. The response of these patients to the psychedelic treatment was promising. The research grew to include hospitalized neurotics who would today be diagnosed as personality disorders, primarily borderline. In 1965, the research at cottage thirteen came to national attention. The CBS television network produced a one hour television documentary, LSD: The Spring Grove Experiment. This film followed the LSD treatment of one male inpatient alcoholic and one female inpatient neurotic. The excellent quality of this documentary drew much positive attention toward the research. The film gave a balanced and responsible yet compelling presentation of the promising new treatment.

Work with LSD Expands

In 1966 tragedy struck this enthusiastic group. A professional member of the Spring Grove research department, a woman in her forties, discovered she had metastatic cancer. Well aware of her terminal prognosis, she became significantly depressed. She knew of the effectiveness LSD psychotherapy had demonstrated with alcoholics and neurotics, so she sought the treatment for herself. In considering her request a literature search revealed work done by a Chicago anesthesiologist, Eric Kast. His study assessed only chemotherapeutic analgesic effects of LSD, but it showed the drug was safe for cancer patients and suggested that LSD might furnish some pain relief. There also was an article in Harpers Magazine on LSD and the anguish of dying by Sidney Cohen (Cohen, 1965). With this support from the literature they forged ahead. The staff member was granted an LSD session. In her own words:

Mainly I remember two experiences. I was alone in a timeless world with no boundaries. There was no atmos¬phere; there was no color, no imagery, but there may have been light. Suddenly I recognized that I was a moment in time, created by those before me and in turn the creator of others. This was my moment, and my major function had been completed. By being born, I had given meaning to my parents’ existence.
Again in the void, alone without the time-space boundaries. Life reduced itself over and over again to the least common denominator. I cannot remember the logic of the experience, but I became poignantly aware that the core of life is love. At this moment I felt that I was reaching out to the world—to all people—but especially to those closest to me. I wept long for the wasted years, the search for identity in false places, the neglected opportunities, the emotional energy lost in basically meaningless pursuits.
Many times, after respites. I went back, but always to variations on the same themes. The music carried and sustained me.
Occasionally, during rests, I was aware of the smell of peaches. The rose was nothing to the fruit. The fruit was nectar and ambrosia (life), the rose was a beautiful flower only. When I finally was given a nectarine it was the epitome of subtle, succulent flavor.
As I began to emerge. I was taken to a fresh wind¬swept world. Members of the department welcomed me and I felt not only joy for myself, but for having been able to use the experience these people who cared for wanted me to have. I felt very close to a large group of people.
Later, as members of my family came, there was a closeness that seemed new. That night, at home, my parents came, too. All noticed a change in me. I was radiant, and I seemed at peace, they said. I felt that way too. What has changed for me? I am living now, and being. I can take it as it comes. Some of my physical symptoms are gone. The excessive fatigue, some of the pains. I still get irritated occasionally and yell. I am still me, but more at peace. My family senses this and we are closer. All who know me well say that this has been a good experience. (Pahnke et al., I970)

The dramatic success of this first attempt launched a major new research focus, the study of psychedelic psychotherapy in the treatment of terminal cancer patients. The work evolved over the next two decades to include some patients that were diagnosed with cancer but not conclusively terminal. In 1967 the results of the first 6 cancer patients were presented by Dr. Walter Pahnke at the American Psychiatric Association meeting.

In 1972 the last LSD study in this series was published. Thirty-one (31) terminally ill cancer patients suffering from anxiety, depression and uncontrollable pain received 200 to 500µg of LSD, usually administered intramuscularly. Multiple sessions were allowed in the study design, but only three patients received more than one session. The early Canadian technique was already being modified to include more psychotherapy and these patients received intensive preparation (6 to 12 hours over 2 to 3 weeks) and follow-up care. Before and after LSD sessions the physical and emotional status of these patients were rated by: physicians, nurses, family members, the LSD therapist and an independent rater. Measurements of narcotic use were also included. On a global measure of improvement that blended the ratings of the observers already mentioned, 9 patients (29%) improved dramatically, 13 patients (42%) were moderately improved and 9 patients (29%) were essentially unchanged. Relief from pain was startling and persisted for a period of weeks or months following the session. This result was statistically significant (p<.001). The amount of narcotic medication decreased but this trend was not statistically significant. There were many complicating factors because other psychoactive medications were involved (phenothiazines, hypnotics and tranquilizers) and not systematically recorded in this study. Also some patients reported that pain that was unbearable before the session became bearable after the session on the same level of narcotic medication (Richards et al., 1972).

Extra-Pharmacological Factors: Set & Setting

The preliminary results of pilot studies with alcoholics, inpatient neurotics, and cancer patients were a reflection of the compelling LSD-psychotherapy treatment within this optimistic and coherent environment of expectations. This dynamic set and setting was a consequence of both conscious and unconscious factors among the research team. The interpersonal environment was designed purposely so that all factors of enthusiasm by the staff might contribute to the patient’s preparation for a profound mystical breakthrough and fundamental life change. The research team’s morale was excellent since they were spending all their time doing this new and exciting treatment. In a powerful way they saw that they even had something to offer the hopeless!

The startling level of improvement using the experimental treatment in alcoholics could best be demonstrated when the results were compared with statistics gathered on patients’ improvement in routine hospital treatment. In study that began in 1963, 69 patients improved significantly on all the scales of the MMPI, except the Hypomania scale. The conclusions were that no patients were harmed and some patients demonstrated substantial improvement. In this very challenging patient population 23 patients (or 33.3% of the sample) were abstinent at the six month follow-up. The result of the conventional approach to treatment at the Alcoholic Unit was only 12% rehabilitation in a prior study of routine Spring Grove Hospital treatment (Kurland et al., 1971 p. 92 and Kurland et al., 1967).

The research team realized that the next logical step was more rigorous study with a control group. Considering Kurland’s earlier research which showed a true double-blind procedure was impossible to maintain, they designed a study with low dose LSD as the control condition. A low dose would produce the physiological effects, mood alterations, and perceptual changes unique to LSD without facilitating a full-blown psychedelic reaction. The mystical or peak experience was regarded as the motivational and transformational catalyst. The use of a 50 µgram dose of LSD as a control would also permit an assessment of the power of a large dose and mystical breakthrough to be contrasted with the emotional catharsis and psychodynamic resolution realizable with a smaller dose. The same highly motivated team would treat both groups. The hypothesis was that only the high dose group would achieve mystical experiences and hence improve the most.

This study involved 135 patients who were randomly assigned to either high dose (450µg) or low dose (50µg) LSD treatment. A battery of psychological tests was administered prior to acceptance in the program and one week after the drug session. The patient’s progress was monitored at 6, 12 and 18 months after completing the therapy program.

One week after the session both treatment groups demonstrated statistically significant improvement in their test scores. The follow-up ratings were made by an independent team of social workers. They indicated that 44 percent of the high dose group were “essentially rehabilitated” at six months. Only 25 percent of the low dose group me this criterion at the same point. Abstinence was 53 percent for the high dose group and 33 percent for the low dose group at six months. This finding was significant statistically (p<.05). At one year post therapy there was no significant difference between the two groups. Yet at one and a half years after treatment, psychedelic psychotherapy had been successful with over half of the alcoholics treated in this program (high and low dose patients combined). Alcoholics receiving conventional therapy had a 12% improvement rate.

The results demonstrated an interesting failure. The team did not fully appreciate the positive impact of its own enthusiasm and esprit de corps so intentionally and carefully cultivated. The inspiration in the team grew, fueled by sharing the mystical breakthroughs of patients undergoing high dose LSD sessions. This further stimulated the already exemplary value placed on human life by the researchers themselves. This motivated group of therapists worked uncommonly well. The 50 µgram control group improved more than expected. A few patients even had full blown mystical experiences on this threshold dose of LSD. Others did quite significant work on their inner conflicts under nearly ideal therapeutic circumstances. At the conclusion of the study, the staff broke the blind and were chagrined at the results, but felt that they had been true to their values and tried their best with all patients. The very hypothesis of this carefully designed study, turned out to be the major problem: Because the “control” was itself LSD, it was a much greater activator of the therapeutic relationship even at a low dose than was previously recognized. The low dose had become another experimental condition rather than the control. The impact of the positive dynamic among the staff was profoundly underestimated. The combination of these drug and non-drug factors produced equivocal results.

Another possible conclusion was that psychotherapy alone was far more effective with alcoholics than suggested by any other study in the literature. However, both the experimental and the “control” groups produced greater improvement than previous studies of routine hospital treatment. Although the search for an adequate control did not meet with success in this study, the role of non-drug factors was demonstrated to be far more powerful than even this research group had anticipated (Kurland et al., 1971).

The Evolution of Paradigms and Therapeutic Approach
From Psychedelic to Psychodelytic Paradigms

Over the years from 1963 to 1976 the therapeutic techniques employed in this research matured and changed. The clinical staff completely changed during this time as well. The beginning psychotherapy research efforts were a direct application of the Canadian technique of psychedelic psychotherapy. The psychedelic (mind manifesting) approach. This technique, as practiced at Spring Grove, used a single large dose of a psychedelic with a specialized environment, eyeshades, headphones and specially selected music. Conventional interpretive psychotherapy was primarily a preparation for the LSD session. In this method there is a preparatory period where the therapist explores the background of the patient with a goal of establishing rapport and preparing the patient for a single overwhelming high dose psychedelic session. When LSD is used in this procedure, the dose ranges from 250 µgrams to 800 µgrams and the session lasts from 8 to 12 hours. Throughout the research endeavor all psychedelic sessions were run by a therapeutic team. The primary therapist and a co-therapist of the opposite sex were in constant attendance throughout the day of the drug session. The morning and early afternoon of the drug session was spent listening to music over stereo headphones with eyeshades to block out the external environment and allow a contemplative inner focus. Musical programs were evolved and eventually a music therapist joined the staff full time. She developed motivational sequences of musical accompaniment for psychedelic therapy. Western classical orchestral and choral music sequences were played to support and express the expansiveness, profundity, sense of sacredness & awesome qualities of the psychedelic experience. The technique aimed to facilitate a breakthrough to transcendental experience (Bonny & Pahnke, 1972). The therapeutic team did not usually offer interpretation but instead offered emotional support and companionship. In the afternoon the patient might sit up and experience visual stimuli, for example pictures of family members. or beautiful art or scenery. Props were used to great effect in psychedelic therapy. A single, long stemmed red rose was part of every session. During the afternoon time was set aside to gaze deeply at the rose under the effects of LSD. Patients were encouraged to look at themselves in a mirror so that they might observe the effects of thinking about their past use of alcohol on their self-image. After the drug session the therapy focus was to consolidate insights and positive motivations for change from the peak or mystical experience into everyday life.

Psycholytic Orientation Exerts Influence

In 1968 Stanislav Grof, a Czechoslovakian psychoanalyst, joined the psychedelic research team. This event marked a time of growth and transition for the therapeutic staff. Grof had developed a complex theoretical schema for understanding the phenomenology of the psychedelic experience and had done much careful work under the Psycholytic approach. The Psycholytic approach involves the use of repeated low doses of psychedelics in a psychoanalytically oriented psychotherapy or a psychoanalysis. The doses used with a drug like LSD would fall in the range 75 µgrams to 250 µgrams. The sessions typically continued for six months to two years. The process involved in-depth analysis of the drug experiences both during and after the drug sessions. The experiential goal of this type of work is to uncover psychodynamically relevant material including repressed childhood memories. It is also useful that psychedelics can enhance the transference and, at the same time, enhance the patients’ insight into their transference toward the therapist.

Grof had already suggested in a paper presented to the European Psycholytic Association that perhaps an integration of the psychedelic method and the psycholytic method would be a valuable approach. Psycholytic therapy produced insight and psychedelic therapy seemed to produce a uniquely powerful motivation toward change. Grof strongly influenced the last years of work at the Research Center. He created a more psychoanalytic atmosphere and the trend toward including more interpretive psychotherapy in psychedelic work blossomed. He proposed a birth paradigm for understanding psychedelic experience and offered a system of interpretation where negative emotional experiences were useful and could be worked through in a systematic way. This supported a therapeutic process that included deeper experiences of conflict with the knowledge that eventually the negative experiences led to transformation, mystical union and re-birth.

As the clinical staff examined patients who returned for additional treatment several years after the original studies, it became apparent that these individuals had experienced a relatively long-term withdrawal from alcohol (up to five years). It seemed that the psychedelic peak therapy provided these individuals with a mystical experience and new insight into the meaning of their lives. The new sense of meaning in their lives slowly diminished following the treatment. This seemed to occur when important conflicts were not completely resolved in the preparatory and post-LSD integrative therapy. Another important factor was that the integration of insights from the LSD session into everyday life was usually incomplete. Despite these shortcomings in their therapy and subsequent adaptation, these individuals had remained sober for significant amounts of time, but when confronted with high-stress life situations, they succumbed to alcohol. The team felt these cases strongly suggested that psychedelic psychotherapy could be improved by including more extensive psychodynamic therapy and additional LSD sessions.

A Melding of Two Approaches:
The Psychodelytic Paradigm

Consequently, the last research conducted with psychedelics at the Maryland Psychiatric Research Center was guided by the extended psychedelic or psychodelytic paradigm 3. This approach involved several high-dose sessions with a psychedelic drug in an environment previously used for psychedelic therapy. The number of sessions increased and the theoretical framework expanded to include a greater emphasis on personal dynamics, perinatal dynamics (Grof, 1976), ego transcendence, and other transpersonal experiences. The thorough exploration of the personal history of the patient was recognized as an important factor contributing to the probability that a peak experience would occur. Thus the aim of this therapeutic approach became to work through the early childhood traumas that surfaced during individual psychotherapy and the early drug sessions.
Conversely, working through was facilitated by later mystical experiences. These profound experiences provided the patient with a deeply experiential, philosophical position from which life had a new meaning: life itself was intrinsically healing. Difficult memories were often accepted easily from the new vantage point. This approach combined the positive aspects of the psychedelic and psycholytic paradigms (Di Leo 1975-76, Grof 1969).
Eventually, the Clinical Sciences Division of the Maryland Psychiatric Research Center conducted several studies using the psychodelytic or extended psychedelic approach with neurotic outpatients and inpatient alcoholics by administering compounds with a shorter duration of action than LSD, such as dipropyltryptamine and psilocybin (Richards and Berendes 1977; Rhead et al., 1977). The results of these studies and a pilot study (Yensen et al., 1975) that explored the use of the milder psychedelic drug MDA (3,4 Methylenedioxyamphetamine) in neurotic outpatients had promising results.
In this later analysis, the psychedelic paradigm appeared to be most useful in work with terminal cancer patients (Richards et al., 1977), whereas the newer, more involved paradigm seemed most promising with neuroses and character disorders (Richards and Berendes, 1977-78; Yensen, 1976).

From Psychodelytic to Holotropic Therapy

Grof evolved a new orientation out of the psychodelytic approach. The new approach he calls holotropic, which means moving or growing toward wholeness. The name and the approach reflect a deeply optimistic view of the intrinsic healing mechanisms released through altered states of consciousness.

On the one hand, the Holotropic modality does not focus directly on resistances, but instead relies on the effects of the altered state of consciousness to erode or explode resistance and defense. This leads at its worst to an attitude that regards the psychedelics as inherently therapeutic. If a resolution does not occur in one session then another session is indicated. This is a valuable formulation because it allows the therapeutic relationship to evolve and develop, but it is weak because it ignores the possibility of a therapeutic impasse. As a consequence, the need for therapist skill to interpret material from a psychedelic session is not stressed.

On the other hand, Grof offers a rich map of the territory of the inner psychedelic journey. This theory links emotion from childhood experiences to global pools of affect associated with the birth trauma. The intensification of the altered state leads finally to breakthroughs into the transpersonal unconscious and many varieties of experience beyond the time & space boundaries of the ego. This is the farthest reaching and most meticulously detailed map of consciousness produced in western scientific research into the human psyche. It links the innermost depths of the psyche with the essential fabric of the universe (Grof, 1988).

The Political Context
New facilities and changing funding patterns

By 1969 the Governor of Maryland, Spiro T. Agnew, inaugurated a large four-story building with an attached 200 person auditorium. The basement had a sensory isolation tank, two sound-proof sensory isolation rooms and a psychophysiology facility with EEG and mini-computer. The third floor was the basic sciences floor with several laboratories. The second floor of this building was devoted to the Clinical Sciences Division and housed two completely self-contained treatment suites with private bathrooms and small kitchens. These rooms were decorated with art, sofa and overstuffed chairs, in the relaxed manner of a comfortable living room. The staff of the entire Research Center included over one hundred people. A primary focus was to be psychedelic research. This included the development of new compounds, isolation of active ingredients in plant materials and capacity to perform basic toxicity assessments with animals.

Conflict with the Hospital Staff

At the same time that this pristine, air-conditioned building sprouted on a hill overlooking the old state hospital buildings, new federal legislation cut funding for state hospitals.

There was strong political pressure to move institutionalized patients out of state hospitals and into community settings. The new legislation created community mental health centers that absorbed much of the funding previously devoted to the state hospitals. Many members of the state hospital staff grew jealous and angry towards the well salaried, highly credentialed, predominantly white, staff of the fancy new air-conditioned Research Center. Meanwhile their own working conditions steadily deteriorated. Studies of inpatients done during this time, compared “routine hospital treatment” to experimental procedures. It is important to note the animosity that this situation engendered between the formerly cooperative and enthusiastic staff of the state hospital and the suddenly more privileged research staff.

This context also may account for the great difference in results between the studies done with inpatients and those done with outpatients during this time. Only the inpatient studies that used the “routine hospital treatment” as the control group were affected by the jealousy of the hospital staff. Only these studies had problematic results that failed to demonstrate the efficacy shown in earlier studies. Public concern about possible chromosome damage was raised in 1967. An in vitro study was published in the journal Science which reported a higher chromosomal aberration rate in white blood cell cultures to which LSD had been added (Cohen et al., 1967). A series of in vivo studies followed, mostly performed on users of illicit LSD. These studies produced contradictory results due to some major shortcomings of the experiments. The studies had no adequate controls and no measurement of the chromosome breakage rate prior to LSD use. Since the furor over these reports had implications for human research with LSD, our group decided to investigate this area in collaboration with the National Institute of Health. In 1969, Tjio, Pahnke, and Kurland reported on a study done at Spring Grove State Hospital: a prospective, double-blind controlled experiment with 32 hospitalized alcoholic or neurotic patients who had never taken LSD prior to the study. This study was the largest and the only one to date that controlled for other drugs taken, concurrent infections, and used pure LSD of known dosage. The results of the study gave no evidence that LSD damages the chromosomes of human subjects given pure pharmaceutical quality LSD. Although early reports were widely publicized, this later careful research was summarily ignored by the popular press. (Tjio et al., 1969)

Other dramatic changes were also taking place at the Research Center. In 1971, Walter Pahnke, Director of Clinical Sciences, died in a scuba diving accident. He had been an energetic, charismatic leader in the research team. His successor as Director of Clinical Research, although a board certified psychiatrist, had no background in psychedelic research.

Scientists were quickly recruited to fill the research positions that threatened to vanish from future budgets if not filled within a few months of their creation. As many, hastily retained, investigators arrived to the Center, they brought their own areas of interest. Through this process the focus of divisions other than Clinical Sciences, strayed from the original vision of a multidisciplinary center to study psychedelics to include a broad gamut of research in basic sciences as it related to psychiatry. During this time the popular press continued sensational coverage of the negative effects of LSD abuse. The State Hospital staff’s attitude toward the research continued its rapid decline.

Hospitalized Neurotic Study

Work with neurotics progressed at Spring Grove alongside the studies with alcoholics. In 1973 Oliver Lee McCabe reported on a study of 96 patients, 31 received a high LSD dose (350 µgrams), 31 a low LSD dose (50 µgrams) and 37 control subjects who received a combination of therapeutic measures as prescribed by the hospital staff. This control therapy was varied and included psychotropic medication, electro-shock therapy, individual psychotherapy & group psychotherapy on the hospital ward. The patients were nominally hospitalized chronic severe neurotics, but most of them met the now more carefully defined criteria for a more severe borderline diagnosis.

Immediately following the treatment program all three groups improved significantly. High dose LSD treatment appeared superior to conventional treatment on 19 measures. Low dose LSD seemed superior to conventional treatment on 11 measures. The improvement was not just a reduction in psychopathology but also reflected and increase in measures of positive mental health.

At six months following the therapy all groups showed significant improvement in functioning. There were no statistically significant differences between groups at this point. At one year there were a few measures that favored the high dose LSD group over conventional treatment. The samples were considered skewed at this point and no longer representative of the original group. At 18 months there was no difference between the groups.

This study was beset by low dose responders and was confounded by the broad scope of neurotic disorders treated. There were problems randomizing males and females and different diagnoses. There was a suggestion that the single or double dose approach was inadequate for this level of pathology. In addition, the women in this study “tended to develop a protracted transference neurosis which was only partly resolved in the course of the treatment.” (Savage et al., 1973 p. 43). Savage’s comments raise a concern as to how adequately the psychedelic therapists were trained to manage transference in this difficult population.

Heroin Addict Study

Savage and McCabe published a paper in 1973 describing a controlled study of thirty-six (36) male heroin addicts in a halfway house. The treatment model included daily urine monitoring, several weeks of preparatory therapy and one high dose (200 to 500 µg) LSD session. Thirty-seven (37) patients randomly assigned to the control group received daily urine surveillance and weekly group therapy in an outpatient abstinence program.

Abstinence data significantly favored the LSD group during the one year follow-up.. Nine (25 % of the 36 subjects in the LSD group) maintained complete abstinence for one year. Two (5% of the 37 subjects in the control group) remained abstinent over the same period. Three LSD patients relapsed briefly and then remained abstinent for the rest of the year. This brings the total abstinent among the LSD group to 12 (33%). Additional research with outpatients was suggested (Savage & McCabe, 1973).

Other Research Projects

In spite of political and journalistic pressures and some equivocal results, the research expanded and diversified. The Clinical Sciences Division ran studies with alcoholics, heroin addicts, inpatient neurotics, outpatient neurotics and instituted a unique program for professionals to have a “training experience” with LSD. The drugs explored included LSD, DPT (Dipropyltryptamine), MDA (3, 4-Methylenedioxyamphetamine), DOET (2,5-Dimethoxy-4-Ethyl Amphetamine), Psilocybin, and, as an active placebo, the stimulant Ritalin (Methylphenidate HCl).

LSD Training Program for Mental Health Related
Professionals

Beginning in June of 1969 a program was instituted to provide one to three LSD training sessions to mental health professionals. This program sought to provide subjects with a better understanding of: 1) the unconscious or primary process 2) the problems of young people involved in drug abuse 3) how better studies of psychedelic drugs might be designed 4) better insight into their own minds and enhancement of their therapeutic skills including empathy. Two hundred three (203) professionals received one to three LSD sessions in this program between 1969 and 1976.

In follow-up reports many trainees reported considerable benefits from their LSD sessions. These positive reports included profound insights into philosophical and religious systems, relief from emotional and psychosomatic symptoms, enhanced feelings of well-being and overall improved functioning. Many of these changes were confirmed by family members and professional colleagues (Harari & Kashof, 1972 give an account of their subjective experiences in this program).

Alcoholism and a New Psychedelic

A low dose DPT pilot study with inpatient alcoholics was reported in 1973. This was the last study conducted where a positive relationship existed between the research center staff and the Alcohol Rehabilitation Unit staff at Spring Grove. There was an initial double-blind assessment of low doses of DPT on measures of interview depth and quality (Soskin et al., 1973), and then 51 patients were treated in a non-double-blind format. The results were “dramatic improvement” from pre to post-treatment on a variety of psychological test variables many of which reached high levels of statistical significance. At six months follow-up five variables were measured: 1) occupational adjustment improved (p<.01), 2) residential adjustment improved (p<.02), interpersonal adjustment improved (p<.001), abstinence (p<.001), global adjustment improved (p<.001) (Grof et al., 1973).

Federal funds were secured to follow-up on these extremely promising results. The outcome of this final alcoholic study (conducted during the time described above when staff relationships were in extreme distress) was published in 1977. The study assigned 175 patients randomly to three treatment groups: DPT therapy, conventional therapy and routine hospital treatment. This regimen was completed by 103 of the original 175 patients. The research center staff conducted both the conventional therapy and the DPT therapy. The hospital staff conducted the routine hospital treatment. There was a differential dropout rate between the DPT group and the other groups. Many patients assigned to the DPT group dropped out of treatment. Earlier discussion of the dynamics with the Alcohol rehabilitation unit describe the atmosphere of competition and fear promulgated at this time.

This study is an example of the effects of non-drug factors on outcome. These equivocal results were obtained when the state hospital staff felt their treatment was pitted against the Research Center staff. This created a hostile environment for the patients undergoing the psychedelic treatment. There were no significant differences between the three groups. The composition of the follow-up groups was confounded because of difficulty in locating patients (Rhead et al., 1977).

With so many confounding variables this study defied straightforward analysis. One conclusion is that DPT is not effective as a treatment for alcoholism. This contradicts earlier findings from this team but confirms one other study (Another conclusion might be that the quality of therapy was not the same as that in the encouraging pilot work, since there was only a partial overlap of clinical staff between the two studies. The concurrent studies with outpatients indicate that the staff performance was at high levels with that population. This suggests that the dynamics with the state hospital staff may be significant.

Outpatient Studies

In contrast to these inpatient DPT studies, Richards published a paper in 1976 with terminal cancer patients. The results were overwhelmingly positive and reflected the research staff’s continued high level of motivation and enthusiasm (Richards et al., 1976).

In another outpatient study Yensen published a report on ten outpatient neurotics using MDA as an adjunct to psychotherapy. The therapy process lasted two to six months with a maximum of 75 hours. Two to four MDA sessions were given with doses ranging from 75 mg to 200 mg. There were standardized assessments before and after treatment and a six month follow-up. Statistically significant psychological improvement (reduction of obsessive-compulsive traits, depression and anxiety) was demonstrated after therapy and remained stable over six months follow-up. Measures of self actualization and sense of well-being also increased significantly. Mean global improvement was significant at the p<0.01 level at follow-up (Yensen, 1976).

There were two studies begun at the research center that have not been mentioned in the literature to date because they were never completed. One was a large (150 subjects) and ambitious study designed by Yensen, Richards, Rhead, Williams and Di Leo. This study involved outpatient psychotherapy with a neurotic population. DPT was the psychedelic drug used and both sterile water and Ritalin (Methylphenidate) served as inactive and active placebos. There is evidence in the literature that Ritalin has use as an adjunct to psychotherapy in addition to its effects as a stimulant. The study involved six groups and both psycholytic style therapy and extended psychedelic style therapy; two of these groups were double-blind controls for DPT in a psycholytic format. Low dose DPT, Ritalin or sterile water were administered in double blind fashion up to 25 times. High dose DPT and marathon music sessions completed the active treatment groups and a waiting list control was the sixth group. This quite involved study attempted to control for expectations and various types of drug action. A grant was submitted to NIMH and a site visit was made but the project received approval with no funding. Nonetheless the staff treated a few patients with this protocol.

The second incomplete and unpublished project involved the referral of outpatients already engaged in psychotherapy with professionals in the surrounding communities. These treating therapists could refer patients they felt were at an impasse in their therapy for consultation with the research center clinical staff and evaluation for possible psychedelic sessions with LSD, DPT or MDA. The referring therapist was free to assist in the psychedelic session. Less than ten patients received sessions in this fashion. (Berendes, 1979)

The Demise of the Research Center

In 1975 there was a great controversy over the dismissal of three scientists from the Basic Sciences division of the research center. The controversy flourished amidst news reports of a suicide due to the CIA’s irresponsible practices with LSD. The estranged scientists accused the research center director of mismanaging public money, and alleged that the research center engaged in no real treatment and thus rendered no service to the people of the state of Maryland.

This political contention led to the eventual transfer of the facility from the Department of Health and Mental Hygiene to the University of Maryland. News stories broke about research with LSD at Edgewood Arsenal (an Army weapons research facility) in Maryland where recruits were given LSD without informed consent. This research was linked to the University of Maryland and created unbearable political pressure to discontinue all psychedelic research at the University of Maryland. As a consequence all psychedelic research at the center was stopped, most of the staff was dismissed or resigned and a new director was appointed. By 1978 there were only five of the original staff employed at the research center and the basic research direction was shifted to schizophrenia research.

Studies after 1976: Psychedelic Research After MPRC

By the end of 1976 over 700 patients had been treated by this team of investigators. The results of these studies include a preponderance of positive results and some perhaps just as interesting equivocal outcomes.

Yet the tide was shifting already. A news report came out about a government agent who the CIA slipped LSD a few days before he jumped out a window in the 1950′s. This report came to the attention of the Maryland legislature which provided the funding for the Research Center. They decided to close down this controversial research and turn the big white building toward research with more conservative psychiatric treatments.

In 1976 the Research Center was completely restructured and virtually the entire professional staff was replaced. The director was relieved of his responsibilities and the psychedelic work was completely eliminated. The success of this research empire went bust in 1976. Why, what happened and what can we learn that is of value to us in our efforts to continue the exploration, to meet the scientific challenge and therapeutic promise of psychedelic drugs?

In 1979 a small group of investigators from the previously disbanded Research Center team began meeting again to plan a way to continue the interrupted research projects. This team met with some success in dealing with the FDA and secured a new Investigational New Drug Permit for LSD as well as reactivating the previous IND for work with terminal cancer patients. Approximately 10 cancer patients were treated through a collaboration with the University of Maryland and North Charles General Hospital. These results have not yet been published (Di Leo, 1993).

Non-Drug Assisted Therapies Evolved from Psychedelic
Research

As with the outer space exploration program sponsored through NASA 4, there have been some new techniques developed out of psychedelic research that do not depend on drug adjuvants and have diffused into the culture of psychotherapy.

Holotropic Breathwork (Grof Breathing)

In the middle 1980′s Stanislav & Christina Grof developed an approach to therapy that involves the use of intense breathing and specially selected stereophonic music. This approach is taught internationally and has spread to many countries. The breathwork session produces phenomena which Grof has described as equivalent to the profound experiential sequences he described for patients undergoing psycholytic and psychedelic therapy (Grof, 1985)

Guided Imagery and Music (GIM)

This technique was developed at the Research Center by Helen Bonny, the staff music therapist. It emerged from a blending of Guided Affective Imagery techniques developed by Hanscarl Leuner in Germany and music therapy approaches she developed for psychedelic work. In this method the patient reclines and enters a deeply relaxed trance while listening to carefully prepared classical music sequences designed to elicit and support death rebirth mystical sequences of experience (Bonny & Savary 1973).

Perceptual Affective Therapy (PAT)

Perceptual Affective Therapy developed as a technique to emulate the effects of psychedelic drugs through the selection and management of audio-visual stimuli to enhance and amplify the inner feeling state of the patient. During a Perceptual Affective Therapy session the patient may alternate between visual deprivation and sensory overload through the alternation of eye shades and intense visual stimuli from slide & motion picture projectors. The patient is induced to enter an altered state by encouraging them to let the stimuli become their feelings and visa versa and to breathe in the stimuli (Yensen, 1981). More recently deep tissue bodywork and breathwork have been integrated with the Perceptual Affective Approach.

Shamanic Paradigm in a Contemporary Frame

In an attempt to integrate experience from Western psychedelic research, contact with contemporary shamanic healers in Mexico and group process, Richard Yensen and Donna Dryer developed a ritual context for psychospiritual healing. This involves the use of breathwork and sensory overload within an anamnestic group journey. While held within the compelling energy of group process in a shared vessel for healing participants undergo an all night healing journey that blends all these elements. Great emphasis is placed on affective, biographical, intellectual and spiritual integration of this experience. The all night ceremony or velada 5is the experiential centerpiece of a 5 to 6 day residential retreat.

Current Status of Psychedelic Research in the United
States

Within the United States we are aware of at least four psychedelic projects. Rick Strassman at the University of New Mexico is pursuing systematic human psychopharmacology of DMT (N,N-Dimethyltryptamine) and Psilocybin (Strassman, 1993). Charles Grob and his associates at Harbor Hospital (UCLA) are involved in safety studies of MDMA (3,4-Methylenedioxymethamphetamine) with mental health professionals and will soon proceed with clinical efficacy studies of terminal cancer patients (Grob, 1993). Juan Sanchez-Ramos and Deborah Mash are proceeding with dose-response studies and safety trials of Ibogaine at the University of Miami (Doblin, 1994). Kurland, Yensen and Dryer have FDA approval for a study involving 60 outpatients with a substance abuse disorder who will receive various doses of LSD in a psychodelytic approach (Kurland et al., 1991).

Future Directions for Research and Training

Fifty years of LSD research has failed to demonstrate that double blind placebo controlled studies are appropriate to study the effects on humans. The adequacy of this method, for instance, whether a double-blind is actually possible, needs to be tested in a study specifically focused on validity of assessment. We are in the process of designing such a study. It will attempt to systematically map, cross-check and control extraneous variables and subjective distortions. The publication of such a study in a peer reviewed journal will open the scientific dialogue necessary if the findings question this accepted method of study. If they do not then we can go forward with a solidly confirmed scientific foundation. If double-blind is not feasible we must develop other rigorous approaches.

Clearly there are many wonderful new tools to assess the physiology and brain metabolic actions of psychedelics. Psychotherapy research with these compounds strongly indicates that physiological response often mirrors subjective experience. For this reason a report of the subjective experience is an important element in data gathering that must not be overlooked in any physiological study. Rick Strassman’s studies are exemplary in this regard. We encourage researchers who use sensitive new techniques such as the PET scanner to correlate the physiology with the psychology of the psychedelic experience. This subjective scope should in not compromise the rigor of such work. Instead it should reflect the intimate connection between mind and body established by psychoneuroimmunology.

In reviewing this work it seems clear that the experimental treatment in psychedelic therapy involves a mystical experience. The presence or absence of this experience is the true experimental condition, not the presence, absence or dose of a psychedelic. This insight suggests another method for analyzing even studies that have already been done. This also substantiates the need for human experimentation as laboratory animals cannot communicate subjective experience with adequate resolution.

The ability to predict which patients are likely to have a peak experience would allow effective selection of the best candidates for treatment. Mechanisms for adequate reporting of non-pharmacological factors in all human research must be discerned. These factors are so uniquely important to the study of psychedelic drugs in human subjects that if they are not systematically reported and studied they merely confound results. Thus set & setting, attitude of all present in a session, institutional politics and psychodynamic interplay are essential reagents in the psychedelic reaction. They must be assessed and reported for replication to be possible.

The assessment of subjective experience is a frontier that directly intersects with psychedelic research. Our tools in this area are by and large primitive, but measurement is imperative. At the research center the Psychedelic Experience Questionnaire was routinely used to quantify the depth of peak experiences. McClelland’s work in psychoneuroimmunology indicates that peak experiences have a profound effect on the immune system. Perhaps new tools will involve direct measurement of immune function as an indicator of peak experience intensity (McClelland, 1988).

Regulatory & Training Issues

Psychedelics pose a challenge to the existing regulatory mechanisms because they are unique in their ability to amplify the effects of extra-pharmacological factors. The regulatory apparatus was established to deal with substances whose effects are consistent and independent of extrapharmacological factors. It would be irresponsible to release psychedelic compounds as prescription drugs. Any physician, psychiatrist, psychologist, or scientist wishing to use psychedelic compounds in human studies must be carefully and extensively trained in their use. That training must reflect our knowledge of their long history of use in other cultures. Models for training come from other subjective disciplines such as psycho¬analysis. Psychoanalysis requires extensive first hand experience in a training analysis. A prospective psychedelic researcher must work with these substances under the careful supervision of more experienced researchers. Most assuredly it is inappropriate for these drugs to be administered by those who refuse to thoroughly explore their own psyche with them as a necessary precondition for responsibly and sensitively dealing with another human being’s response to the same compounds.

Interdisciplinary approaches are imperative The disciplines of psychology, anthropology, philosophy and theology must not be excluded merely because we conceive of these compounds as drugs and of drugs as the exclusive province of physicians. The

Consciousness Laboratory

The use of computers, virtual reality, and physiological measurement could be integrated into a nearly ideal laboratory for psychedelic research. Such an environment would allow free access to a tremendous variety of audio-visual stimuli to enhance and manage response to the compounds while still permitting un¬obtrusive measurement of physiological states and their subsequent correlation with the experiences facilitated by psychedelics in this setting. The advantage of this setting is that it would thoroughly document the stimuli used, the drug, dosage and psychological response all in real-time with possibilities for feedback into the on-going drug session (Yensen, 1982).

Summary

The role of usually ignored and unreported extra-pharmacological factors in psychedelic research has been explored with the Spring Grove and MPRC studies as examples. The relationships among the entire research team have quite significant impact on the milieu for psychedelic research. These factors of set & setting play a major role by increasing or decreasing the probability of a peak experience. We found the peak experience to be the actual treatment condition not the presence or absence of a psychedelic. The psychedelic is another contributing factor, one that enhances the likelihood of a peak experience, but does not guarantee it.

Consistently errors were made in underestimating the impact of non-drug factors on psychedelic sessions and their outcome. Training sessions that provide study designers with enough first hand experiences to understand the phenomenological shifts that occur with psychedelics would be helpful.

As we explore the evolution of more effective therapy with psychedelics there is need for more systematic and complete reporting of all non-drug variables. If these important reagents in the psychedelic reaction are not reported the work cannot be replicated.

The appropriateness of double-blind methodology and indeed the possibility of a true double blind has been called into question. This is a testable research hypothesis that we propose to investigate.

In the process of conducting the research at Spring Grove and the Maryland Psychiatric Research Center over 750 patients received psychedelic sessions. The majority benefited in some way, a minority were unchanged. We are not aware of any long-term complications among the subjects. This establishes a solid basis for future investigations in terms of risk to benefit ratio.

We need a rigorous and systematic approach to investigating the therapeutic potential of psychedelic compounds as enhancers of the healing process. We must use the insights available from past efforts in this culture and others to develop this investigational capacity.

Summary Listing of Major Studies

Cholden, Kurland & Savage, 1955
20 inpatients with chronic schizophrenia
LSD 100-500µg Intramuscular Injection
up to 14 administrations given daily
Conclusions
1) LSD can be given I.M. over protracted period without untoward effects
2) Tolerance is seen on the 2nd day and after 4-6 days is gone
3) Gross behavior is useful indicator of tolerance
4) There is no cross tolerance between LSD and mescaline
5) Clinical responses of schizophrenics were categorized
6) The reactions may in part be determined by the milieu

Kurland, Unger, Shaffer, Savage, 1967
69 chronic alcoholic inpatients
LSD 200-900 µg orally
1 administration
18 month follow-up study
Conclusions
1) Safe treatment modality as shown by pre- and post- EEG’s on 20 patients
2) Specialized training is necessary for safe an effective treatment
3) One-third maintained abstinence up to 6 months
4) Reversal of pattern of pathological functioning as seen on MMPI’s

Pahnke, Kurland, Goodman, Richards, 1969
22 metastatic cancer inpatients
LSD 200-500µg
Conclusions
Pilot study and case histories: 6 showed dramatic improvement, 8 showed good
improvement, 8 remained unchanged of 22 Improvement: decreased depression, anxiety, fear of death; increased relaxation, greater ease in medical management, closer interpersonal family relationships with more openness and honesty on a 13 point scale

Tjio, Pahnke, Kurland, 1969
32 psychiatric inpatients, 5 drug abusers & 8 normals
LSD 21 high dose=250-400 µg; 11 low dose=50 µg
Conclusions
Mean pre-LSD rate of chromosomal aberrations in the 32 patients (4.28%) and the 5 LSD users (2.81%) are comparable to each other and to the values obtained from 2 normal control subjects sampled for 8 to 10 consecutive days (2.65%). Pre- to post-LSD differences for both the 32 patients (+1.63%) and the 5 LSD users (+0.76%) are not statistically significant. Mean chromosomal aberration rates for the 32 patients and 5 LSD users (including both pre-and post-means), 8 experimental normal LSD subjects (post-LSD), and 2 normal controls (no LSD) only vary from 2.65% to 5.91%.

Pahnke, Kurland, Unger, Savage, Wolf, Goodman, 1970
6 metastatic cancer patients
LSD 200µg to 300 µg orally or intramuscular
Conclusions
case histories; showed decrease in need for pain medication and improvement in global change for all 6 patients

Pahnke, Kurland, Unger, Savage, Grof, 1970 JAMA
Experimental Use of Psychedelic Psychotherapy
overview

Kurland, Savage, Pahnke, Grof & Olsson 1971
135 chronic alcoholics
LSD 50µg or 450µg orally
one session
6, 12, and 18 mo follow-up
Conclusions
6 month follow-up 53% rehabilitated high dose group vs. 33% in low dose group p=.05. This initial gain was attenuated at end of 18 months although overall levels of improvement was considerably better for both groups than usual improvement for other alcoholics in the same setting without LSD-assisted psychotherapy.

Richards, Grof, Goodman, Kurland, 1972
31 cancer patients
LSD 200-500 µg orally or intramuscular
one session
Conclusions
25% had peak experiences and less fear of death afterwards 29% dramatically improved, 41.9% moderately improved, 29% unchanged McCabe, Savage, Kurland, Unger, 1972 96 inpatient neurotics LSD 31 high dose (350µg), 32 low dose (50µg), 33 group therapy alone Conclusions High dose psychedelic therapy was superior to conventional therapy on specific “symptom” areas as defined by the MMPI, e.g.. depression, obsessive-compulsive syndrome, social introversion, manifest anxiety, ego strength, neurotic overcontrol. On the POI “Spontaneity” and “Self-regard” consistently show greater increments after both forms of psychedelic therapy and “self-actualized values” are more frequently increased after high-dose LSD administration.

Savage, McCabe ,Kurland, Hanlon, 1973
same 96 inpatient neurotics as above
more complete data analysis
Conclusions
High dose>Conventional treatment
p<.05 for MMPI items Depression, Social Introversion, Ego Strength, Benaric Items
p<.01 for Validity, Correction, Factor, Social Desirability. for POI items p<.05 for Self-actualizing value, and Self-Acceptance and p<.01 for Spontaneity and Self-regard for PEP items p<.05 Distress, Distrust, Social Desirability, Future p<.01 for Insight
Low Dose better than Conventional Treatment p<.01 only for PEP Distrust and Distress and POI Self-Regard and p<.05 for MMPI scales Correction, Factor, Social Desirability, PEP scales Future and Insight and POI Spontaneity.

Soskin, Grof, Richards, 1973 18
inpatient alcoholics
15-30 mg of DPT intramuscular
Conclusions
Therapist Rating Scale DPT > placebo p<.01 for items: Recall of Memories and Experiences, Emotional Expressiveness, depth of Self-Exploration and p<.05 for Psychodynamic Resolution.

Grof, Soskin, Richards, and Kurland, 1973
51 inpatient alcoholics
15-150 mg DPT intramuscular
one to six two-hour sessions
72 DPT and 64 placebo therapy interviews on a double-blind basis
Conclusions
Percentage rehabilitated at 6 month follow-up: global adjustment=46.8% and abstinence=53.2% at p<0.001 and significant improvement (compared to pre-treatment) on occupational adjustment (p<.01), residential adjustment (p<.02), interpersonal adjustment (p<.001).

Savage and McCabe, 1973 37
narcotic addicts in a halfway house
200-500 µg LSD orally
one session
Conclusions
25% remained abstinent vs. 5% abstinent at 12 month follow up with p<.05

Turek, Soskin, Kurland, 1974
10 mental health professionals
MDA 40-150mg orally
one session Pilot Study
Conclusions
Analyzed blood pressure, digit symbol subtest, digit span subtest, handwriting, Psychedelic Experience Questionnaire, Modified Linton-Langs Questionnaire and the Subjective Drug Effects Questionnaire. MDA invites inner exploration vs. LSD which demands it. Might be helpful in treatment of obsessive and depressive traits.

Yensen, Di Leo, Rhead, Richards, Soskin, Turek, Kurland, 1976
10 neurotic outpatients
MDA 75-200 mg orally
2-4 sessions
Conclusions
Significant improvements on POI, MMPI, BPRS, WPRS, and Social History Questionnaire at pre- to post and 6 months post therapy

Rhead, Soskin, Turek, Richards, Yensen, Kurland, Ota, 1977
33 inpatient alcoholics received DPT, compared to 46 Conventional Treatment (CT), 24 Routine Hospital Treatment (RHT)
DPT 15-150mg intramuscular injection
1-6 sessions
Conclusions
Not much difference due to drop-out rates and other complexities discussed in this paper.

Richards,, Rhead, Di Leo, Yensen, Kurland, 1977
34 cancer patients
75-127.5 mg DPT intramuscular injection
one session
Conclusions
Predictors of peak experiences analyzed (peakers=14, non-peakers=17)

Richards, Rhead, Grof, Goodman, Di Leo, Rush, 1979
30 cancer patients
75-127.5 mg DPT intramuscular injection
one session
Conclusions
ECRS scales of Depression and Anxiety were p<.05 pre- vs. post- Mini-Mult showed decreased distress, e.g. D p<.006, Hy p<.006, Pt p<.004, Pa p<.01, Sc p<.001, Ma p<.02; POI: Time competency p<.03, Inner Directedness p<.01, Self-Regard p<.02, Self-Acceptance p<.005, Capacity for Intimate contact p<.02.

Berendes, 1979
12 neurotic outpatients
20-30 mg psilocybin or 200-300µg LSD or 70-120 mg DPT
one session in the context of ongoing psychoanalytic psychotherapy
Conclusions
Analytic description of shifts in therapy and transference leading up to, during, and after the session.

Footnotes

1. Mescaline HCl was used rather than mescaline sulfate because it was more soluble and easier to prepare for intramuscular injection.

2. This finding is contradicted by later studies with mescaline sulfate in animals and humans. Yet mescaline does not affect 5HT2 receptors while LSD does.

3. This name was suggested by Stanislav Grof in an address to the European Psycholytic Association (Grof, 1969).

4. National Aeronautics & Space Administration.

5. The velada is a Mazatec ritual in which psychedelic mushrooms are used to enter a deep altered state of consciousness for healing. In this modern shamanic approach multimedia portrayals of death re-birth sequences, breathwork and deep tissue bodywork are used to produce the altered state rather than psychedelics.

References

Berendes, M. Formation of Typical Dynamic Stages in Psychotherapy Before and After Psychedelic Drug Intervention. Journal of Altered States of Consciousness, 1979, 5, 4, 325-338.

Bonny, H. & Pahnke, W.N. The Use of Music in Psychedelic (LSD) Therapy. Journal of Music Therapy, 1972, 9, 64-87.

Bonny, H. & Savary, L. Music and Your Mind. New York: Harper, 1973.

Cholden, L.S., Kurland, A. A. & Savage, C. Clinical Reactions and Tolerance to LSD in Chronic Schizophrenia. The Journal of Nervous and Mental Disease, 1955, 122, 3, 211-221.

Cohen, M., Marinello, M., & Bach, N. Chromosomal Damage in Human Leukocytes Induced by Lysergic Acid Diethylamide. Science, 1967, 155, 1417-1419.

Cohen, S. LSD and the Anguish of Dying, Harpers Magazine. 1965, 231, pp. 69-88.

Di Leo, F. The Use of Psychedelics in Psychotherapy. Journal of Altered States of Consciousness, 1975, 2, 4, 325-337

Di Leo, F.B. Personal Communication, 1993.

Di Leo, F.B. The Activation and Experiential Integration of In-Depth Psychic Introjects in Psychedelic-Activated Psychotherapy. International Journal of Eclectic Psychotherapy, 1982, 1, 1, 33-55.

Doblin, R. FDA Approves Human Studies with Ibogaine. Multidisciplinary Association for Psychedelic Studies, Winter 1994, 4, 3, p. 4.

Grob, C. Personal Communication, 1993.

Grof, S. Psycholytic and psychedelic therapy with LSD: Toward an integration of approaches. Address to the Conference of the European Association for Psycholytic Therapy, Frankfurt, West Germany, October 1969.

Grof, S. Realms of the Human Unconscious: Observations from LSD Research. New York: Viking Press, 1975.

Grof, S. The Adventure of Self-Discovery. New York: SUNY Press, 1988. Grof, S., Goodman, L.E., Richards, W.A. & Kurland, A.A. LSD-Assisted Psychotherapy in Patients with Terminal Cancer. International Phamacopsychiatry, 1973, 8, 129-144.

Grof, S., Soskin, R.A., Richards, W.A. & Kurland, A.A. DPT as an Adjunct in Psychotherapy of Alcoholics. International Pharmacopsychiatry, 1973, 8, 104-115.

Harari, C. & Kashoff, S. A Guided Psychedelic Experience: Subjective Report. Voices: The Art and Science of Psychotherapy, 1972, 8, 4, 45-59.

Kurland, A.A., Savage, C., Pahnke, W.N., Grof, S. & Olsson, J.E. LSD in the Treatment of Alcoholics. Pharmakopsychiatrie Neuro-Psychopharmakologie, 1971, 4, 2, 84-94.

Kurland, A.A., Shaffer, J.W. & Unger, S. Psychedelic Psychotherapy in the Treatment of Alcoholism (An Approach to a Controlled Study). Excerpta Medica International Congress Series No. 129, 1966.

Kurland, A.A., Shaffer, J.W., Savage, C., Wolf, S., Leihy, R., McCabe, O.L. & Shock, H. LSD-Type Drugs and Psychedelic Therapy. Research in Psychotherapy, 1968, 3, 521-534.

Kurland, A.A., Unger, S., Shaffer, J.W. & Savage, C. Psychedelic Therapy Utilizing LSD in the Treatment of the Alcoholic Patient: A Preliminary Report. American Journal of Psychiatry, 1967, 123, 10, 1202-1209.

McCabe, O.L. & Hanlon, T.E. The Use of LSD-Type Drugs in Psychotherapy: Progress and Promise. In McCable, O.L. (Ed) Changing Human Behavior: Current Therapies and Future Directions. Grunne & Stratton, 1977.

McCabe, O.L., Savage, C., Kurland, A.A. & Unger, S. Psychedelic (LSD) Therapy of Neurotic Disorders: Short Term Effects. Journal of Psychedelic Drugs, 1972, 5, 1, 18-28.

McClelland, D.C. & Kirshnit, C. The Effect of Motivational Arousal Through Films on Salivary Immunoglobulin A. Psychology and Health, 1988, 2, 31-52.

Pahnke, W.N., Drugs and Mysticism: An Analysis of the Relationship Between Psychedelic Drugs and Mystical Consciousness. (Doctoral Dissertation, Harvard University) 1963.

Pahnke, W.N., Kurland, A.A., Goodman, L.E. & Richards, W.A. LSD-Assisted Psychotherapy with Terminal Cancer Patients. In Hicks, R.E. & Fink, P.J. (Eds) Psychedelic Drugs. New York: Grunne & Stratton, 1969, 33-42.

Pahnke, W.N., Kurland, A.A., Unger, S., Savage, C. & Grof, S. The Experimental Use of Psychedelic (LSD) Psychotherapy. Journal of the American Medical Association, 1970, 212, 11, 1856-1863.

Pahnke, W.N., Kurland, A.A., Unger, S., Savage, C., Wolf, S. & Goodman, L.E. Psychedelic Therapy (Utilizing LSD) with Cancer Patients. Journal of Psychedelic Drugs, 1970, 3, 1, 63-75.

Rhead, J.C., Soskin, R.A., Turek, I., Richards, W.A., Yensen, R., Kurland, A.A. & Ota, K. Y. Psychedelic Drug (DPT)-Assisted Psychotherapy with Alcoholics: A Controlled Study. Journal of Psychedelic Drugs, 1977, 9, 4, 287-300.

Richards, W., Grof, S., Goodman, L. & Kurland, A. LSD-Assisted Psychotherapy and the Human Encounter with Death. Journal of Transpersonal Psychology, 1972, 4, 2, 121-149.

Richards, W.A. & Berendes, M. LSD-Assisted Psychotherapy and Dynamics of Creativity: A Case Report. Journal of Altered States of Consciousness, 1977, 3, 2, 131-146.

Richards, W.A., Rhead, J.C., DiLeo, F.B., Yensen, R. & Kurland, A.A. The Peak Experience Variable in DPT-Assisted Psychotherapy with Cancer Patients. Journal of Psychedelic Drugs, 1977, 9, 1, 1-10.

Richards, W.A., Rhead, J.C., Grof, S., Goodman, L.E., Di Leo, F.B. & Rush, L. DPT as an Adjunct in Brief Psychotherapy with Cancer Patients. Omega, 1979, 10, 1, 9-26.

Savage, C. & McCabe, O.L. Residential Psychedelic (LSD) Therapy for the Narcotic Addict: A Controlled Study. Archives of General Psychiatry, 1973, 28, 808-814.

Savage, C. Psychedelic Therapy. Research in Psychotherapy, 1968, 3, 512-520.

Savage, C., Hughes, M.A. & Mogar, R. The Effectiveness of Psychedelic (LSD) Therapy: A Preliminary Report. The British Journal of Social Psychiatry, 1967, 2, 1, 59-66.

Savage, C., McCabe, O.L., Kurland, A.A. & Hanlon, T. LSD-Assisted Psychotherapy in the Treatment of Severe Chronic Neurosis. Journal of Altered States of Consciousness, 1973, 1, 1, 31-47.

Soskin, R.A., Grof, S. & Richards, W.A. Low Doses of Dipropyltryptamine in Psychotherapy. Archives of General Psychiatry, 1973, 28, 817-821.

Stace, W.T. Mysticism and Philosophy. New York: Lippincott, 1960.

Strassman, R. Personal Communication, 1993.

Tjio, J., Pahnke, W.N. & Kurland, A.A. LSD and Chromosomes A Controlled Experiment. Journal of the American Medical Association, 1969, 210, 5, 849-856.

Turek, I.S., Soskin, R.A. & Kurland, A.A. Methylenedioxyamphetamine (MDA) Subjective Effects. Journal of Psychedelic Drugs, 1974, 6, 1, 7-13.

Unger, S. The Psychedelic Use of LSD: Reflections and Observations. In Psychedelic Drugs. New York: Grunne & Stratton, 1969.

Yensen R. From Mysteries to Paradigms: Humanity’s Journey from Sacred Plants to Psychedelic Drugs. In: Rätsch C, ed. Gateway to Inner Space: Sacred Plants, Mysticism and Psychotherapy. Dorset: Press, 1989: 11-53

Yensen, R. The Thousand Petalled Lotus and the Computer: A Tale of a Powerful Tool for the New Age. Paper presented at the Seventh International Transpersonal Conference in Bombay, India, 1982.

Yensen, R., DiLeo, F.B., Rhead, J.C., Richards, W.A., Soskin, R.A., Turek, B. & Kurland, A.A. MDA-Assisted Psychotherapy with Neurotic Outpatients: A Pilot Study. Journal of Nervous and Mental Disease, 1976, 163, 4, 233-245.

Yensen, R., Kurland, A.A. & Dryer, D. The Relationship Between Peak Experience And Outcome In LSD Assisted Psychotherapy With Substance Abusers, A Double-Blind Controlled Study. Protocol submitted to Food & Drug Administration, 1991.

This article is based on an address to the European College of Consciousness (ECBS) International Congress, Worlds of Consciousness in Göttingen, Germany 24 27 September 1992.

Richard Yensen, Ph.D., Director, Orenda Institute, 4324 West 15th Avenue, Vancouver, British Columbia V6R 3A8, ryensen(at)orenda.org

Donna Dryer, M.D., M.P.H., Medical Director, Orenda Institute

2012 and Human Destiny End of the World or Consciousness Revolution?

By Stanislav Grof

Since the publication of Jose Arguelles’ book The Mayan Factor: Path Beyond Technology (Arguelles 1987) brought to the attention of lay audiences the ancient prophecy concerning the end of the Maya Long Count calendar, which started on August 11, 3114 BC, and will end on December 21, 2012 AD, this date has become the focus of many articles, books, and conferences and of a forthcoming movie entitled 2012. Similar prophecies about the end of the Great Cycle can be found in many other cultural and religious groups – the Hopi, Navajo, Cherokee, Apache, Iroquois confederacy, ancient Egyptians, the Kabbalists, Essenes, Qero elders of Peru, the Subsaharan Dogon tribe, and the Australian Aborigines.
With a few exceptions, the Mayan prophecy about the end of the cosmic cycle, the Fifth World, has been interpreted in terms of actual physical destruction of humanity and of the material world, in a way similar to the interpretation (or better misinterpretation) of the term apocalypse by Christian fundamentalists, particularly the millions of American Christians who believe that at the time of this global destruction they will experience “rapture” and be united with Jesus. People who see it this way are not aware of the fact that the original and literal meaning of the term apocalypse (Greek Aποκάλυψις Apokálypsis) is not destruction but “lifting of the veil” or “revelation.” It referred to the disclosure of some secrets hidden from the majority of humanity to certain privileged persons. The source of the misinterpretation of this word is probably the phrase “apokálypsis eschaton” which literally means “revelation at the end of the æon, or age.”
The purpose of this conference is to explore a radically different, more optimistic interpretation of the Mayan prophecy – as referring to the end of the world as we have known it: a world dominated by unbridled violence and insatiable greed, egotistic hierarchy of values, corrupted institutions and corporations, and irreconcilable conflicts between organized religions. Instead of predicting a physical destruction of the material world, the Mayan prophecy might refer to death and rebirth and a mass inner transformation of humanity. In order to explore this idea, we have to answer two important questions, First, how could ancient Mayans two thousand years ago predict what situation humanity would be facing in the twenty-first century? And second, are there any indications that modern society, more specifically the industrial civilization, is currently on the verge of a major psychospiritual transformation? I will try to address these questions in this course of my presentation.
The Mayan prophecy concerning the 2012 winter solstice has an important astronomical dimension. Over 2,000 years ago the early Maya formulated a profound galactic cosmology. Being excellent observers of the sky, they noticed that the position of the winter solstice sun was slowly shifting toward an alignment with the galactic axis. This movement is caused by so called precession – the wobble of the rotational axis of the earth. The Mayans concluded that major changes of cosmic proportions would occur at the time of this auspicious solar/galactic alignment. This is an event that happens only every 25,920 years, which is the period required for the equinox to move through all twelve zodiacal signs. C. G. Jung used in his book Aion and in his other writings the term “Platonic Month” for the period that it takes the vernal equinox point to pass through one constellation of the sidereal zodiac (approximately 2160 years) and the term “Platonic Year” for the completion of the entire zodiacal cycle.
Astronomers of the pre-classic Maya culture called the Izapa Culture devised the Long Count calendar consisting of thirteen baktuns to target the time when the cosmic alignment would maximize – December 2012 AD. The cultural legacy of ancient Mayans includes stone monuments conveying in carved glyphs and images the prophecy concerning this auspicious alignment. The above facts make it clear why the list of presenters to this conference should include people like John Major Jenkins, who has spent two decades studying Mayan archeological records trying to understand their original meaning (Jenkins 1998, 2002) or Robert Sitler, who has spent extensive time with contemporary Mayans and can offer deep insights into their culture (2006). It is also obvious that an accomplished astrologer and historian like Richard Tarnas would be able to make a vital contribution to the main theme of the conference (Tarnas 2006).
My own area of interest in the last fifty years has been research of non-ordinary states of consciousness or, more specifically, an important subcategory of these states for which I coined the term holotropic. This composite word means literally “oriented toward wholeness” or “moving in the direction of wholeness” (from the Greek holos = whole and trepein = moving toward or in the direction of something). These are states that novice shamans experience during their initiatory crises and later induce in their clients. Ancient and native cultures have used these states in rites of passage and in their healing ceremonies. They were described by mystics of all ages and initiates in the ancient mysteries of death and rebirth. Procedures inducing these states were also developed in the context of the great religions of the world – Hinduism, Buddhism, Taoism, Islam, Judaism, and Christianity (Grof 2000, 2006).
It is less immediately evident and requires some explanation why and how experiences and observations from the study of holotropic states can throw new light on the problem of the Mayan prophecy. The key consideration in this regard is that powerful consciousness-expanding procedures (“technologies of the sacred”) played an integral and essential role in the Mayan culture. We have ample pictorial evidence on Mayan stone stelae, sculptures, and ceramics that they used for this purpose the Mexican cactus peyote (Lophophora williamsii), magic mushrooms (Psilocybe mexicana or coerulescens known to the Indians asXibalba okox or teonanacatl), and skin secretions of the toad Bufo marinus. Additional plant materials used in pre-Hispanic Mesoamerica were the morning glory seeds (Ipomoea violacea) called by the natives ololiuqui, Salvia divinatorum, also known as diviner’s sage, wild tobacco (Nicotiana rustica), and balche (a fermented drink made from the tree Lonchocarpus longistylus and honey).
A powerful and specifically Mayan mind-altering technique was massive bloodletting induced by using lancets made of stingray spines, flint, or obsidian to wound the tongue, earlobes, and genitals (Schele and Miller 1986, Grof 1994). Ritual bloodletting opened up an experiential realm that was not ordinarily accessible before the time of biological death. The Mayans used the symbol of the Vision Serpent for the experiences induced by blood loss and shock. This symbol represented the contact between the everyday world of human beings and the world of gods and sacred ancestors, who were expected to appear in their visions in the supernatural realms. The lancet was perceived as a sacred object with enormous power; it was personified in the form of the Perforator God.
Because of the extraordinary importance that these “technologies of the sacred” had in the Mayan culture, it is reasonable to assume that visionary experiences induced by them might have provided inspiration for the prophecy concerning 2012 and played a major role in its articulation. It is thus fully justified to look at this prophecy through the prism of the discoveries of modern consciousness research.
In holotropic states of consciousness, it is possible to obtain profound revelations concerning the master blueprint of the universe designed by cosmic intelligence of such astonishing proportions that it is far beyond the limits of our everyday imagination. Individuals experiencing psychedelic states, including myself, occasionally reported that they had profound illuminating insights into the creative dynamics of the Kosmos. More specifically, psychedelic pioneer Terence McKenna described in his preface to John Major Jenkins’ book Maya Cosmogenesis 2012 that he received his insights concerning 2012 in his mushroom sessions.
Individuals who had such illuminating cosmic visions suddenly understood that what is happening in the material world is formed and informed by archetypal principles, beings, and events existing in dimensions of reality that are inaccessible for our everyday consciousness. They also saw that the dynamics of the archetypal world is systematically correlated with the movements of the planets, their angular relationships, and their relative positions to the fixed stars. This led to a completely new understanding of astrology, its origins, and paramount importance. It became clear to them that the source of astrology were global encompassing visions of the workings of the Kosmos and not tedious accumulation of individual observations of correlations between events in the world and celestial bodies.
Richard Tarnas, amassed over a period of more than thirty years impressive and convincing evidence for systematic correlations existing between the archetypal world, celestial dynamics, and psychological and historical processes and presented it in his groundbreaking and paradigm-breaking book Cosmos and Psyche (Tarnas 2006). Rick’s astrological research has focused primarily on correlations with the movements of the planets, but there exist astrological systems, which pay great attention to fixed stars; experiences in holotropic states can provide equally revealing insights in this regard.
An important aspect of experiences in holotropic states is that they transcend narrow linear time and make it possible to see events in the universe on a cosmic astronomical scale. In all their grandeur, time scales like the Mayan Long Count Calendar or the Great or Platonic Year are very modest as compared to others inspired by visionary experiences, such as those found in Tantric science, in which the age of the universe amounts to billions of years (a number similar to the assessment of modern cosmologists), or to those discussed in Hindu religion and mythology, such as the kalpas or the Day of Brahman that also amounts to billions of years. The visions of ancient Mayan seers could thus with the help of “technologies of the sacred” easily reach many centuries into the future.
The Mayan prophecy concerning the galactic alignment is not limited to astronomical observations and astrological predictions; it is intimately interconnected with mythology, with what C. G. Jung called the archetypal domain of the collective unconscious. For example, the Mayan seers referred to the December solstice sun as “Cosmic Father” and to the Milky Way as “Cosmic Mother. They envisioned the center of the galaxy, where modern astronomy places a giant black hole, as her creative and destructive womb. The time of the galactic alignment was thus the time of a cosmic hieros gamos, sacred marriage between the Feminine and the Masculine.
In the year 2012, the sun will have traveled to the edge of a cosmic dust cloud known as the Great Dark Rift that lies along the Milky Way and seems to divide its light into two paths. The Mayans called this dark rift Xibalba Be (Road to the Underworld) and saw it as a place of birth and death and of death/rebirth. It was for them the birth canal of the Cosmic Mother Creatrix, where the December solstice sun gets reborn in 2012. It was also a death place, because it is the doorway into the underworld, the land of the dead and the unborn. These associations clearly were not products of everyday fantasy and imagination of the Mayans projected on the night sky, but results of profound direct apprehensions of the connection between the archetypal world and the celestial bodies and processes.
The Mayan prophecy has also an important mythological connection to the story about the Hero Twins, Hunahpu and Xbalanque, who were invited by the death gods to visit the underworld Xibalba and play ballgame with them. The Xibalba Lords put them through many ordeals and the brothers overcame them all and, finally, they died and were reborn as the Sun and the Moon (or according to some interpretations as the Sun and Venus). The part of the story that seems particularly relevant in this regard is the battle of the twins with the bird demon Vucub-Caquix (“Seven-Macaw”); he is a vain, selfish, and impulsive ruler, who pretends to be the sun and the moon of the twilight world in between the former creation and the present one. He seems to represents the ego archetype that is dominant at the end of the cycle. Seven Macaw seems to have an archetypal parallel in the New Testament -– the Endtime Ruler or the “Beast,” also known as Antichrist.
Hunahpu and Xbalanque defeat Seven Macaw and strip him of his teeth (the instrument of violence), of his riches, and his power. By doing this, they facilitate the resurrection of their father, One Hunahpu, a just ruler who represents selfless divine consciousness that is holistic; it shows concern for all beings, and makes political decisions based upon future generations or – as Native Americans say – with regard to how they will affect seven generations down the road.
Research of holotropic states – psychedelic therapy, holotropic breathwork, and work with individuals in “spiritual emergencies” – made major contributions to the understanding of mythology. Myths are commonly considered to be products of human fantasy and imagination not unlike stories of modern fiction writers and playwrights. However, the work of C. G. Jung and Joseph Campbell brought about a radically new understanding of mythology. According to these two seminal thinkers, myths are not fictitious stories about adventures of imaginary characters in nonexistent countries and thus arbitrary products of individual human fantasy. Rather, myths originate in the collective unconscious of humanity and are manifestations of primordial organizing principles of the psyche and of the cosmos which Jung called archetypes (Jung 1976).
Archetypes express themselves through the individual psyche and its deeper processes, but they do not originate in the human brain and are not its products. They are superordinate to the individual psyche and function as its governing principles. In holotropic states the archetypal world can be directly experienced in a way that is as convincing and authentic as the material world appears to be, or more so. To distinguish transpersonal experiences involving archetypal figures and domains from imaginary products of individual fantasy, Jungians refer to this domain as imaginal.
French scholar, philosopher, and mystic, Henri Corbin, who first used the term mundus imaginalis, was inspired in this regard by his study of Islamic mystical literature (Corbin 2000). Islamic theosophers call the imaginal world, where everything existing in the sensory world has its analogue, ‘alam a mithal,’ or the “eighth climate,” to distinguish it from the “seven climates,” regions of traditional Islamic geography. The imaginal world possesses extension and dimensions, forms and colors, but these are not perceptible to our senses as they would be if they were properties of physical objects. However, this realm is in every respect as fully ontologically real and susceptible to consensual validation by other people as the material world perceived by our sensory organs.
Archetypes are timeless essences, cosmic ordering principles, which can also manifest as mythic personifications, or specific deities of various cultures. The figures of Maya mythology – Hunahpu, Xbalanque, Seven Macaw, Quetzalcoatl (Kukulcan), and others – like those of any other culture are thus ontologically real and can be directly apprehended by individuals experiencing holotropic states. As John Major Jenkins pointed out, Giorgio de Santillana and Hertha von Dechend contributed to the understanding of archetypes another important dimension that is relevant for the problem of the Mayan prophecy. They described in their book Hamlet’s Mill the deep connection that exists between myth and astronomical processes (de Santillana and Dechend 1969).
In 1948, after many years of systematically studying mythologies of various cultures of the world, Joseph Campbell published his ground-breaking book The Hero with a Thousand Faces, which in the following decades profoundly influenced research and understanding in the field (Campbell 1968). Analyzing a broad spectrum of myths from various parts of the world, Campbell realized that they all contained variations of one universal archetypal formula, which he called the monomyth. This was the story of the hero, either male or female, who leaves his or her home ground and, after fantastic adventures culminating in psychospiritual death and rebirth, returns as a deified being. The story of the Mayan Hero Twins is a classical example of Campbell’s Hero’s Journey. It belongs to a vast array of archetypal motifs that we can experience in holotropic states.
I hope that the above discussion adequately addressed the first question that I asked earlier in my presentation: “How could ancient Mayans two thousand years ago discover anything that would be relevant for humanity in the twenty-first century?” The theme of Joseph Campbell’s Hero’s Journey brings us to the second question: “If the Mayan prophecy does not refer to the end of the world and to physical destruction of humanity, but to profound collective psychospiritual death and rebirth comparable to what Campbell described on the individual scale, are there any indications that such inner transformation is possible or that it actually is already underway.
My approach to this question is based not only on observations of the experiences of thousands of individuals in holotropic states of consciousness – psychedelic therapy, holotropic breathwork sessions, and spontaneous psychospiritual crises (“spiritual emergencies”) – but also on extensive personal experience of these states. I would like to begin this discussion with an account of an experiential sequence from one of my own psychedelic sessions. It provided for me deep insights into the archetype of the Apocalypse, a motif that occurs relatively rarely in holotropic states, but is particularly relevant for the topic of our conference.

About fifty minutes into the session, I started experiencing strong activation in the lower part of my body. My pelvis was vibrating as enormous amounts of energy were being released in ecstatic jolts. At one point, this streaming energy swept me along in an intoxicating frenzy into a whirling cosmic vortex of creation and destruction. In the center of this monstrous hurricane of primordial forces were four giant herculean figures performing what seemed to be the ultimate cosmic saber dance. They had strong Mongolian features with protruding cheekbones, oblique eyes, and clean-shaven heads decorated by large braided ponytails. Whirling around in a frantic dance craze, they were swinging large weapons that looked like scythes or L-shaped scimitars; all four of these combined formed a rapidly rotating swastika. I intuitively understood that this monumental archetypal scene was related to the beginning of the process of creation and simultaneously to the final stage of the spiritual journey. In the cosmogenetic process (in the movement from the primordial unity to the worlds of plurality) the blades of the scimitars represented the force that is splitting and fragmenting the unified field of cosmic consciousness and creative energy into countless individual units. In relation to spiritual journey, they represented the stage when the seeker’s consciousness transcends separation and polarity and reaches the state of original undifferentiated unity. The direction of this process seemed to be related to the clockwise and counterclockwise rotation of the blades. Projected into the material world, this archetypal motif seemed to be related to growth and development (the fertilized egg or seed becoming an organism) or destruction of forms (wars, natural catastrophes, decay). Then the experience opened up into an unimaginable panorama of scenes of destruction. In these visions, natural disasters, such as volcanic eruptions, earthquakes, crashing meteors, forest fires, floods and tidal waves, were combined with images of burning cities, entire blocks of collapsing high-rise buildings, mass death, and horror of wars. Heading this wave of total annihilation were four archetypal images of macabre riders symbolizing the end of the world. I realized that these were the Four Horsemen of the Apocalypse. (pestilence, war, famine, and death). The continuing vibrations and jolts of my pelvis now became synchronized with the movements of this ominous horseback riding and I became I joined the dance, becoming one of them, or possibly all four of them at once, leaving my own identity behind. Suddenly, there was a rapid change of scenery and I had a vision of the cave from Plato’s Republic. In this work, Plato describes a group of people who live chained all of their lives in a cave, facing a blank wall. They watch shadows projected on the wall by things passing in front of the cave entrance. According to Plato, the shadows are as close as the prisoners get to seeing reality. The enlightened philosopher is like a prisoner who is freed from this illusion and comes to understand that the shadows on the wall are illusory, as he can perceive the true form of reality rather than the mere shadows seen by the prisoners. This was followed by profound and convincing realization that the material world of our everyday life is not made of «stuff» but created by cosmic consciousness by infinitely complex and sophisticated orchestration of experiences. It is a divine play that the Hindus call lila, created by cosmic illusion maya. The final major scene of the session was a magnificent ornate theater stage featuring a parade of personified universal principles, archetypes – cosmic actors, who through a complex interplay create the illusion of the phenomenal world. They were protean personages with many facets, levels, and dimensions of meaning that kept changing their forms in extremely intricate holographic interpenetration as I was observing them. Each of them seemed to represent simultaneously the essence of his or her function and all the concrete manifestations of this element in the world of matter. There was Maya, the mysterious ethereal principle symbolizing the world illusion; Anima, embodying the eternal Female; a Mars-like personification of war and aggression; the Lovers, representing all the sexual dramas and romances throughout ages; the royal figure of the Ruler; the withdrawn Hermit; the elusive Trickster; and many others. As they were passing across the stage, they bowed in my direction, as if expecting appreciation for the stellar performance in the divine play of the universe. 

This experience brought me a deep understanding of the meaning of the archetypal motif of the Apocalypse. It suddenly seemed profoundly wrong to see it as related exclusively to physical destruction of the world. It is certainly possible that the Apocalypse will in the future be actually manifested on a planetary scale as a historical event, which is a potential of all archetypes. There are many examples of situations in which archetypal motifs and energies broke through the boundary that usually separates the archetypal realm from the material world and shaped history. The giant asteroid that 65 million years ago killed the dinosaurs, wars of all ages, the crucifixion of Jesus, the medieval Witches’ Sabbath and Dance of Death, the Nazi concentration camps, and Hiroshima are just a few salient examples. But the primary importance of the archetype of the Apocalypse is that it functions as an important landmark on the spiritual journey. It emerges into the consciousness of the seeker at a time when he or she recognizes the illusory nature of the material world. As the universe reveals its true essence as virtual reality, as a cosmic play of consciousness, the world of matter is destroyed in the psyche of the individual. This might also be the meaning of the “end of the world” referred to in the Mayan prophecy.
The observations from modern consciousness research that are most relevant for a positive interpretation of the Mayan prophecy are related to a phenomenon that is much more common in holotropic states than the experience of the Apocalypse; it is the experience of psychospiritual death and rebirth. This experience has played a crucial role in the ritual and spiritual history of humanity – in shamanism, rites of passage, the ancient death/rebirth mysteries, and in the great religions of the world (see the Christian concept of being “born again” and the Hindu “dvija“). The process of death and rebirth is a multivalent archetype that manifests on many different levels and in various areas and ways, but in self-exploration and therapy it is closely related to the reliving and conscious integration of the memory of biological birth.
Psychospiritual death and rebirth is one of the most prominent themes in therapeutic work using holotropic states. When the age regression in the process of deep experiential selfexploration moves beyond the level of memories from childhood and infancy and reaches the level of the unconscious that contains the memory of birth, we start encountering emotions and physical sensations of extreme intensity, often surpassing anything we previously considered humanly possible. At this point, the experiences become a strange mixture of the themes of birth and death. They involve a sense of a severe, life-threatening confinement and a desperate and determined struggle to free ourselves and survive.
Because of the close connection between this domain of the unconscious and biological birth, I have chosen for it the name perinatal. It is a Greek-Latin composite word where the prefix peri- means “near” or “around,” and the root natalis signifies “pertaining to childbirth.” This word is commonly used in medicine to describe various biological processes occurring shortly before, during, and immediately after birth. The obstetricians talk, for example, about perinatal hemorrhage, infection, or brain damage. However, since traditional medicine denies that the child can consciously experience birth and claims that this event is not recorded in memory, one never hears about perinatal experiences. The use of the term perinatal in connection with consciousness reflects my own findings and is entirely new (Grof 1975).
The perinatal region of the unconscious contains the memories of what the fetus experienced in the consecutive stages of the birth process, including all the emotions and physical sensations involved. These memories form four distinct experiential clusters, each of which is related to one of the stages of the birth process. I have coined for them the term Basic Perinatal Matrices (BPM IIV). BPM I consists of memories of the advanced prenatal state just before the onset of the delivery. BPM II is related to the onset of the delivery when the uterus contracts, but the cervix is not yet open. BPM III reflects the struggle to be born after the uterine cervix dilates. And finally, BPM IV holds the memory of the emerging into the world, the birth itself. The content of these matrices is not limited to fetal memories; each of them also provides selective opening into a vast domain in the unconscious psyche that we now call transpersonal. This involves experiential identification with other people and other life forms, ancestral, racial, collective, phylogenetic and karmic memories, and material from the historical and archetypal collective unconscious, which contains motifs of similar experiential quality. Emergence of this material into consciousness constitutes the process of psychospiritual death and rebirth and results in deep inner transformation.
Some of the insights of people experiencing holotropic states of consciousness are directly related to the current global crisis and its relationship with consciousness evolution. They show that we have exteriorized in the modern world many of the essential themes of the death rebirth process that a person involved in deep personal transformation has to face and come to terms with internally. The same elements that we would encounter in the process of psychological death and rebirth in our visionary experiences make today our evening news. This is particularly true in regard to the phenomena that characterize what I refer to as the third Basic Perinatal Matrix (BPM III)(Grof 2000).
As I mentioned earlier, this matrix is related to the stage of birth when the cervix is open and the fetus experiences the tedious propulsion through the birth canal. This stage is associated with the emergence of the shadow side of human personality – murderous violence and excessive or deviant sexual drives, scatological elements, and even satanic imagery. It is easy to see manifestations of these aspects of the death rebirth process in today’s troubled world.
We certainly see the enormous unleashing of the aggressive impulse in the many wars and revolutionary upheavals in the world, in the rising criminality, terrorism, and racial riots. Equally dramatic and striking is the lifting of sexual repression and freeing of the sexual impulse in both healthy and problematic ways. Sexual experiences and behaviors are taking unprecedented forms, as manifested in the sexual freedom of adolescents, premarital sex, gay liberation, general promiscuity, common and open marriages, high divorce rate, overtly sexual books, plays and movies, sadomasochistic experimentation, and many others.
The demonic element is also becoming increasingly manifest in the modern world. Renaissance of satanic cults and witchcraft, popularity of books and horror movies with occult themes, and crimes with satanic motivations attest to that fact. Terrorism of the fundamentalist fanatics and groups is also reaching satanic proportions. The scatological dimension is evident in the progressive industrial pollution, accumulation of waste products on a global scale, and rapidly deteriorating hygienic conditions in large cities. A more abstract form of the same trend is the escalating corruption and degradation of political, military, economic, and religious institutions, including the American presidency.
Ancient Mayans showed profound interest in death and in the process of death and rebirth. Much of the Mayan ritual and art was dedicated to the process of death, from the soul’s entrance into the underworld called Xibalba to a final rebirth and apotheosis. Mayan mythology and funereal art described death as a journey whose challenges were known and its important stages were depicted on coffins, wall paintings, pottery, jades, and other objects that accompanied the deceased during the great transition.
Unfortunately, no specific eschatological texts comparable to the Egyptian or Tibetan Book of the Dead have survived from the Mayan Classical Period, since much of the Maya literary legacy has been lost for posterity. Only a few codices, accordion-like bark paper screenfolds with rich and colorful illustrations, survived the hot and moist climate of Central America and escaped the ravaging of the Spanish invaders.” However, in the 1970s, mayologists Lin Crocker and Michael Coe were able to distinguish a group of funeral vessels painted in the style of the Maya codices, probably by the same artists. Cardiosurgeon and archeologist Francis Robicsek was able to assemble substantial evidence for his theory that “certain sequences of the vases of the ‘ceramic codex,’ placed in proper sequence, actually represented a Maya Book of the Dead” (Robicsek 1981).
Observations from the research of holotropic states of consciousness have thrown new light on human propensity to unbridled violence and insatiable greed – two forces that have driven human history since time immemorial and are currently threatening survival of life on this planet. This research has revealed that these “poisons,” as they are called in Tibetan Vajrayana, have much deeper roots than current biological and psychological theories assume – biology with concepts like the naked ape, the triune brain, and the selfish gene and psychoanalysis and related schools with their emphasis on base instincts as the governing principles of the psyche.
Deep motivating forces underlying these dangerous traits of human nature have their origin on the perinatal and transpersonal levels of the psyche, domains that mainstream psychology does not yet recognize (Grof 2000). The finding that the roots of human violence and insatiable greed reach far deeper than mainstream academic science ever suspected and that their reservoirs in the psyche are truly enormous could in and of itself be very discouraging. However, it is balanced by the exciting discovery of new therapeutic mechanisms and transformative potentials that become available in holotropic states on the perinatal and transpersonal levels of the psyche.
We have seen over the years profound emotional and psychosomatic healing, as well as radical personality transformation, in many people who were involved in serious and systematic experiential self-exploration and inner quest. Some of them had supervised psychedelic sessions, others participated in holotropic breathwork workshops and training or various other forms of experiential psychotherapy and self-exploration. Similar changes occur often in individuals who are involved in shamanic practice or are meditators and have regular spiritual practice. We have also witnessed profound positive changes in many people who received adequate support during episodes of spontaneous psychospiritual crises (“spiritual emergencies”). Thanatologist Ken Ring referred to this group of transformative experiences as “Omega experiences” and included in it near-death experiences and alien abduction experiences (Ring 1984).
As the content of the perinatal level of the unconscious emerges into consciousness and is integrated, the individuals involved undergo radical personality changes. They experience considerable decrease of aggression and become more peaceful, comfortable with themselves, and tolerant of others. The experience of psychospiritual death and rebirth and conscious connection with positive postnatal or prenatal memories reduces irrational drives and ambitions. It causes a shift of focus from the past and future to the present moment and enhances zest, élan vital, and joie de vivre – ability to enjoy and draw satisfaction from simple circumstances of life, such as everyday activities, food, lovemaking, nature, and music. Another important result of this process is emergence of spirituality of a universal and mystical nature that, unlike the dogmas of mainstream religions, is very authentic and convincing, because it is based on deep personal experience.
The process of spiritual opening and transformation typically deepens further as a result of transpersonal experiences, such as identification with other people, entire human groups, animals, plants, and even inorganic materials and processes in nature. Other experiences provide conscious access to events occurring in other countries, cultures, and historical periods and even to the mythological realms and archetypal beings of the collective unconscious. Experiences of cosmic unity and one’s own divinity result in increasing identification with all of creation and bring the sense of wonder, love, compassion, and inner peace.
What began as a process of psychological probing of the unconscious psyche conducted for therapeutic purposes or personal growth automatically becomes a philosophical quest for the meaning of life and a journey of spiritual discovery. People, who connect to the transpersonal domain of their psyche, tend to develop a new appreciation for existence and reverence for all life. One of the most striking consequences of various forms of transpersonal experiences is spontaneous emergence and development of deep humanitarian and ecological concerns. Differences among people appear to be interesting and enriching rather than threatening, whether they are related to gender, race, color, language, political conviction, or religious belief. Following this transformation, these individuals develop a deep sense of being planetary citizens rather than citizens of a particular country or members of a particular racial, social, ideological, political, or religious group. And they feel the need to get involved in service for some common purpose. These changes resemble those that have occurred in many of the American astronauts who were able to see the earth from outer space (see Mickey Lemle’s documentary The Other Side of the Moon).
It becomes obvious that our highest priorities as biological creatures have to be clean air, water, and soil. No other concerns, such as economic profit, military pursuits, scientific and technological progress, or ideological and religious beliefs, should be allowed to take priority over this vital imperative. We cannot violate our natural environment and destroy other species without simultaneously damaging ourselves. This awareness is based on an almost cellular knowledge that the boundaries in the universe are arbitrary and that each of us is ultimately identical with the entire web of existence.
In view of the fact that everything in nature runs in cycles and is based on the principles of optimum values, homeostasis, and sustainability, the technological civilization’s frantic pursuit of unlimited economic growth, exploitation of non-renewable resources, and exponential increase of industrial pollution hostile to life appears to be dangerous insanity. In the world of biology excess of calcium, vitamins, or even water is not better than lack of these substances and unlimited growth is the main characteristic of cancer.
It is clear that a transformation associated with the experience of psychospiritual death and rebirth would increase our chances for survival if it could occur on a sufficiently large scale. The great German writer and philosopher Johann Wolfgang Goethe was aware of the importance of the experience of psychospiritual death and rebirth for the quality of our life and sense of belonging when he wrote in his poem Selige Sehnsucht: “Und so lang du das nicht hast, dieses: Stirb und werde! Bist du nur ein trüber Gast auf der dunklen Erde.” (And as long as you do not experience this: “Die and become!” you will be only a shadow guest on the dark earth). We can now return to the subject of our conference and of this paper – the Mayan prophecy concerning 2012. Whether or not this was predicted by ancient Mayan seers, we are clearly involved in a dramatic race for time that has no precedent in the entire history of humanity. What is at stake is nothing less than the future of humanity and of life on this planet. Many of the people with whom we have worked saw humanity at a critical crossroad facing either collective annihilation or an evolutionary jump in consciousness of unprecedented nature and dimension. Terence McKenna put it very succinctly: “The history of the silly monkey is over, one way or another” (McKenna 1992). We either undergo a radical transformation of our species or we might not survive.
The final outcome of the crisis we are facing is ambiguous and uncertain; it lends itself to pessimistic or optimistic interpretation and each of them can be supported by existing data. If we continue the old strategies, which in their consequences are clearly extremely destructive and self-destructive, it is unlikely that modern civilization will survive. However, if a sufficient number of people undergoes a process of deep inner transformation, we might reach a stage and level of consciousness evolution at which we will deserve the proud name we have given to our species: homo sapiens sapiens and live in a new world that will have little resemblance to the old one.

Literature

Arguelles, J.: The Mayan Factor: Path Beyond Technology. Rochester, Vermont: Inner Traditions, Bear and Company.

Campbell, J. 1968. The Hero with A Thousand Faces. Princeton: Princeton University Press.

Corbin, H. 2000. “Mundus Imaginalis, Or the Imaginary and the Imaginal.” In: Working With Images (B. Sells, ed.). Woodstock, Connecticut: Spring Publications 71-89.

Grof, S. 1985. Beyond the Brain. Birth, Death, and Transcendence in Psychotherapy. Albany, NY: State University of New York (SUNY) Press.

Grof, S. 1994. Books of the Dead: Manuals for Living and Dying London: Thames and Hudson.

Grof, 2000. Psychology of the Future: Lessons from Modern Consciousness Research. Albany, NY: State University of New York (SUNY) Press

Grof, S. The Ultimate Journey: Consciousness and the Mystery of Death. MAPS, Sarasota, FL, 2006.

Jenkins, J. M. 1998. Maya Cosmogenesis 2012. Rochester, Vermont: Inner Traditions, Bear and Company.

Jenkins, J.M. Galactic Aligment: The Transformation of Consciousness According to Mayan, Egyptian, and Vedic Traditions. Rochester, Vermont: Bear and Company.

Jung, C.G. 1959. The Archetypes and the Collective Unconscious. Collected Works of C.G. Jung. Vol. 9, Bollingen Series XX, Princeton, New Jersey: Princeton University Press.

Jung, C.G. 1959. Aion. Collected Works of C.G. Jung. Vol. 9.2, Bollingen Series XX, Princeton, New Jersey: Princeton University Press.

McKenna, T. 1992. Food of the Gods: The Search for the Original Tree of Knowledge. New York: Bantam Books.

Ring, K. 1984. Heading Toward Omega: In Search of the Meaning of the Near-Death Experience. New York: William Morrow.

Robicsek, F. 1981. The Maya Book of the Dead: The Ceramic Codex. Charlottesville, VA.: University of Virginia Art Museum.

Santillana, G. and and Dechend, H. von. 1977. Hamlet’s Mill: An Essay on Myth and the Frame of Time. Boston: Godine.

Schele, L. and Miller, M.A.: The Blood of Kings: Dynasty and Ritual Art in Maya Art. New York: George Braziller, Inc.

Sitler, R. 2006. The 2012 Phenomenon: New Age Appropriation of an Ancient Mayan Calendar. Nova Religio: The Journal of Alternative and Emergent Religions, Volume 9, issue 3, pp. 24-38.

Tarnas, R. 2006. Cosmos and Psyche: Intimations of a New World View. New York: Viking Press.

© Stanislav Grof 2009

Albert Hofmann, 11. Januar 1906 – 29. April 2008

At the age of 102 years, Albert Hofmann died peacefully last Tuesday morning, 29th April, in his home near Basel, Switzerland. Just last weekend we talked to him, and he expressed his great joy about the blooming plants and the fresh green of the meadows and trees around his house. His vitality and his open mind stayed with him until his last breath. He is renowned as being one of the most important chemists of our times. He was the discoverer of LSD, which he considered as both a “wonder drug” and a “problem child”. In addition he did pioneering work as a researcher of other psychoactive substances, as well as of active agents of important medicinal plants and mushrooms. Under the spell of the consciousness-expanding power of LSD the scientist turned increasingly into a philosopher of nature and a visionary critic of contemporary culture.

Until his death Albert Hofmann remained active. He communicated with colleagues and experts from all over the world, gave interviews, and showed great interest in world affairs, although he had already decided a few years ago to retire from public life. Nevertheless he welcomed visitors at his home on the Rittimatte, and kept the door open until late in the evening.
He managed to keep his almost childlike curiosity for the wonders of nature and creation. In his “paradise,” as he called his home, he enjoyed being close to nature, especially to plants. During one of our last visits he said to us with luminous eyes: “The Rittimatte is my second most important discovery.” It was always a unique experience to stroll with him over his meadows and to share his enjoyment of the living nature all around.

Gratefully and lovingly we grieve for an outstanding scientist, an important philosopher, a dear and true friend, and a member of the board of the Gaia Media Foundation.

Albert Hofmann was born on January 1906 in the quiet small town of Baden, Switzerland, as the eldest of four children. His father was a toolmaker in a factory where he met Albert’s mother-to-be. When his father fell seriously ill Albert had to support the family. That’s why he decided on a commercial apprenticeship. At the same time he started studying Latin and other languages, since he wanted to take his A-levels, which he succeeded in doing at a private school, funded by a godfather.

In 1926, at the age of twenty, Albert Hofmann began to study chemistry at the University of Zurich. Four years later he obtained his doctorate with distinction. Subsequently he worked at the Sandoz pharmaceutical-chemical research laboratory in Basel, a company to which he proved his loyalty continuously for more than four decades. (In 1996 Sandoz and Ciba-Geigy merged to become Novartis.) That’s where he mainly worked with medicinal plants and mushrooms. He was specifically interested in alkaloids (nitrogen compounds) of ergot, a cereal fungus. In 1938 he isolated the basic component of all therapeutically essential ergot alkaloids, lysergic acid; he combined it with a series of chemicals, then tested the effects of these lysergic acid derivatives for action as circulatory and respiratory stimulants — among others LSD-25 (the 25th in the series, lysergic acid diethylamide). However, because the effects observed fell short of expectations the pharmacologists at Sandoz lost interest in it.

Five years later, following a “peculiar presentiment,” Albert Hofmann resumed investigation of LSD-25. On 16 April 1943 while working on synthesizing the compound, he was overcome by unusual sensations — “a remarkable restlessness, combined with a slight dizziness” — which caused him to interrupt his laboratory work.
“At home I lay down and sank into a not unpleasant intoxication-like condition, characterized by an extremely stimulated imagination. In a dreamlike state, with eyes closed (I found the daylight too unpleasantly glaring), I perceived an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors. After some two hours this condition faded away.”

Three days later, on 19 April 1943, Hofmann set out on the first voluntary LSD trip in the history of mankind. Because he did not yet know the enormous potency of the drug, he took 250 micrograms, a fairly high dose, and got to know the hallucinogenic power of the substance in all its intensity.

With his discovery of LSD Albert Hofmann caused a snowball effect, which quickly turned into an avalanche. It influenced the late second millennium — at least in the Western world — to an extent comparable only to the “pill”. Consciousness researchers respectfully spoke of an “atom bomb of the mind.”

Albert Hofmann made essential contributions to research in this field. In 1958 he was the first to succeed in isolating the psychoactive substances psilocybin and psilocin from Mexican magic mushrooms (Psilocybe mexicana). In Ololiuqui, the seeds of a climbing plant (Morning Glory), he found substances related to LSD (the monoethylamide). He isolated and synthesized substances found in important medicinal plants in order to study their effects. His basic research blessed Sandoz with several successful remedies, including Hydergine, effective in geriatrics, Dihydergot, a circulation- and blood-pressure stabilizing medicine, and Methergine, an active agent used in gynecology.

Albert Hofmann stayed with Sandoz until his retirement in 1971, finally as head of the research department for natural medicines. Thereafter he devoted much of his time to writing and lecturing. He increasingly won recognition for his scientific pioneering ventures: he was given honorary doctorates by the ETH Zurich, the University of Stockholm and the Berlin Free University, and he was nominated for the Nobel Prize.

His outstanding contributions to research were rightly honored, but Albert Hofmann’s life’s work comprised much more. From the start he took a favorable view of efforts by physicians and psychotherapists to include LSD in new approaches to the treatment of many chronic diseases. But LSD isn’t only useful with special diagnoses — it was Albert Hofmann’s firm belief that the “psychedelic” potential of this “wonder drug” could be beneficial for us all. In LSD-induced altered states of consciousness its discoverer didn’t see psychotic delusions of a chemically manipulated mind, but rather windows to a higher reality — true spiritual experiences during which a normally deeply buried potential of our mind reveals itself, namely, our unity with the divine aspect of creation. “The one-sided belief of the scientific view of life is based on a far-reaching misunderstanding,” Hofmann says in his book Insight-Outlook. “Certainly, everything it [this view] contains is real — but this represents just one half of reality; only its material, quantifiable part. It lacks all those spiritual dimensions which cannot be described in physical or chemical terms; and it’s exactly these which include the most important characteristics of all life.”

It’s not the single consumer alone who profits from chemicals which help to understand these aspects of the world; for Hofmann it could help to heal deficits the Western world chronically suffers from: “Materialism, estrangement from nature …, lack of professional fulfillment in a mechanized, lifeless world of employment, boredom and aimlessness in a rich, saturated society, the lack of a philosophical basis for making sense of life.” Starting from such experiences as LSD provides, we could “develop a new awareness of reality” which “could become the basis of a spirituality that’s not founded on the dogmas of existing religions, but on insights into a higher and more profound meaning” — in that we recognize, read, and understand “the revelations of the book which God’s finger wrote.”

When such insights “become established in our collective consciousness, it could happen that scientific research and the previous destroyers of nature — technology and industry — will serve the purpose of returning our world to what it formerly was: an earthly Garden of Eden.” With this message the genius chemist turns into a profound philosopher of nature and visionary critic of contemporary culture.

Albert Hofmann never abandoned his critical stance toward the LSD euphoria of the hippie- and flower-power-driven, but that he fathered a “problem child” he had already emphasized with the title of one of his best-known works. He always underlined the risks of uncontrolled use. On the other hand he never tired of emphasizing the basic difference between LSD and most other illicit drugs: even if used repeatedly, LSD is not addictive; it doesn’t reduce one’s awareness; and taken in normal doses it’s absolutely non-toxic.
He could never understand the complete demonizing of psychedelics, as done by the mass media, conservative politicians, and governments from the sixties onward. For him, there is no reason why mentally stable persons in the right set and setting shouldn’t enjoy LSD. He was all the more disappointed when, in the late sixties, he saw it happen that the use of LSD was criminalized worldwide and prohibited — even for therapeutic and research purposes.

The impetus for a change emanating from the impact of the international Symposium “LSD — Problem Child and Wonder Drug” in 2006 in Basel, on the occasion of his 100th birthday, led him to say that “after this conference my problem child has definitely turned into a wonder child,” and he regarded this development as his most beautiful birthday present.
And just shortly before his 102nd birthday, he was pleased to note that the first LSD study with humans received approval from the Federal Office of Public Health in Bern, which he called the “fulfillment of my heart’s desire.”

His life was an ideal for us as to how we can reach a great age in mental and physical vigor by retaining a childlike curiosity. Albert Hofmann repeatedly expressed his conviction that his mystical experiences and his trips into other worlds of consciousness, which he experienced first spontaneously as a child and later during his experiments with psychedelic substances, was the best preparation for the last journey which everybody has to take at the end of their life. He retained this curiosity about his last journey right up to the end.
30 Apr 08

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